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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 2-32947529-G-A (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=2&pos=32947529&ref=G&alt=A&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "2",
"pos": 32947529,
"ref": "G",
"alt": "A",
"effect": "missense_variant",
"transcript": "NM_206943.4",
"consequences": [
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 34,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "NM_206943.4",
"protein_id": "NP_996826.3",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1721,
"cds_start": 205,
"cds_end": null,
"cds_length": 5166,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000404816.7",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_206943.4"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 34,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000404816.7",
"protein_id": "ENSP00000386043.2",
"transcript_support_level": 5,
"aa_start": 69,
"aa_end": null,
"aa_length": 1721,
"cds_start": 205,
"cds_end": null,
"cds_length": 5166,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_206943.4",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000404816.7"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 34,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000929169.1",
"protein_id": "ENSP00000599228.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1749,
"cds_start": 205,
"cds_end": null,
"cds_length": 5250,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000929169.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 34,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000954823.1",
"protein_id": "ENSP00000624882.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1720,
"cds_start": 205,
"cds_end": null,
"cds_length": 5163,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000954823.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 34,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000929163.1",
"protein_id": "ENSP00000599222.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1719,
"cds_start": 205,
"cds_end": null,
"cds_length": 5160,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000929163.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 34,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000929162.1",
"protein_id": "ENSP00000599221.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1693,
"cds_start": 205,
"cds_end": null,
"cds_length": 5082,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000929162.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 34,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000929171.1",
"protein_id": "ENSP00000599230.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1691,
"cds_start": 205,
"cds_end": null,
"cds_length": 5076,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000929171.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000954822.1",
"protein_id": "ENSP00000624881.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1681,
"cds_start": 205,
"cds_end": null,
"cds_length": 5046,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000954822.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000929166.1",
"protein_id": "ENSP00000599225.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1678,
"cds_start": 205,
"cds_end": null,
"cds_length": 5037,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000929166.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 34,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000892679.1",
"protein_id": "ENSP00000562738.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1669,
"cds_start": 205,
"cds_end": null,
"cds_length": 5010,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000892679.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 34,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "NM_001394905.1",
"protein_id": "NP_001381834.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1668,
"cds_start": 205,
"cds_end": null,
"cds_length": 5007,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001394905.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 34,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000892677.1",
"protein_id": "ENSP00000562736.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1668,
"cds_start": 205,
"cds_end": null,
"cds_length": 5007,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000892677.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 34,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000929172.1",
"protein_id": "ENSP00000599231.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1666,
"cds_start": 205,
"cds_end": null,
"cds_length": 5001,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000929172.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000929160.1",
"protein_id": "ENSP00000599219.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1665,
"cds_start": 205,
"cds_end": null,
"cds_length": 4998,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000929160.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000929167.1",
"protein_id": "ENSP00000599226.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1639,
"cds_start": 205,
"cds_end": null,
"cds_length": 4920,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000929167.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000929168.1",
"protein_id": "ENSP00000599227.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1631,
"cds_start": 205,
"cds_end": null,
"cds_length": 4896,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000929168.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000929170.1",
"protein_id": "ENSP00000599229.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1627,
"cds_start": 205,
"cds_end": null,
"cds_length": 4884,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000929170.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000929161.1",
"protein_id": "ENSP00000599220.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1626,
"cds_start": 205,
"cds_end": null,
"cds_length": 4881,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000929161.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000892678.1",
"protein_id": "ENSP00000562737.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1612,
"cds_start": 205,
"cds_end": null,
"cds_length": 4839,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000892678.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000929164.1",
"protein_id": "ENSP00000599223.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1611,
"cds_start": 205,
"cds_end": null,
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"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000929164.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000929173.1",
"protein_id": "ENSP00000599232.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1609,
"cds_start": 205,
"cds_end": null,
"cds_length": 4830,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000929173.1"
},
{
"aa_ref": "A",
"aa_alt": "T",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"missense_variant"
],
"exon_rank": 1,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LTBP1",
"gene_hgnc_id": 6714,
"hgvs_c": "c.205G>A",
"hgvs_p": "p.Ala69Thr",
"transcript": "ENST00000929165.1",
"protein_id": "ENSP00000599224.1",
"transcript_support_level": null,
"aa_start": 69,
"aa_end": null,
"aa_length": 1570,
"cds_start": 205,
"cds_end": null,
"cds_length": 4713,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
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}