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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 2-3453326-G-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=2&pos=3453326&ref=G&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "2",
"pos": 3453326,
"ref": "G",
"alt": "C",
"effect": "intron_variant",
"transcript": "NM_016030.6",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.1531-4295G>C",
"hgvs_p": null,
"transcript": "NM_016030.6",
"protein_id": "NP_057114.5",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 735,
"cds_start": null,
"cds_end": null,
"cds_length": 2208,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2499,
"mane_select": "ENST00000324266.10",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_016030.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.1531-4295G>C",
"hgvs_p": null,
"transcript": "ENST00000324266.10",
"protein_id": "ENSP00000324318.5",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 735,
"cds_start": null,
"cds_end": null,
"cds_length": 2208,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2499,
"mane_select": "NM_016030.6",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000324266.10"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"3_prime_UTR_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.*342G>C",
"hgvs_p": null,
"transcript": "XM_011510354.3",
"protein_id": "XP_011508656.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 517,
"cds_start": null,
"cds_end": null,
"cds_length": 1554,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2691,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_011510354.3"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.1531-4295G>C",
"hgvs_p": null,
"transcript": "ENST00000858088.1",
"protein_id": "ENSP00000528147.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 793,
"cds_start": null,
"cds_end": null,
"cds_length": 2382,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2603,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000858088.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.1531-4295G>C",
"hgvs_p": null,
"transcript": "ENST00000964175.1",
"protein_id": "ENSP00000634234.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 770,
"cds_start": null,
"cds_end": null,
"cds_length": 2313,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2531,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000964175.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.1609-4295G>C",
"hgvs_p": null,
"transcript": "ENST00000858087.1",
"protein_id": "ENSP00000528146.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 761,
"cds_start": null,
"cds_end": null,
"cds_length": 2286,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2516,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000858087.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.1531-4295G>C",
"hgvs_p": null,
"transcript": "ENST00000964174.1",
"protein_id": "ENSP00000634233.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 748,
"cds_start": null,
"cds_end": null,
"cds_length": 2247,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2545,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000964174.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.1531-4295G>C",
"hgvs_p": null,
"transcript": "ENST00000858086.1",
"protein_id": "ENSP00000528145.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 741,
"cds_start": null,
"cds_end": null,
"cds_length": 2226,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2519,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000858086.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.1531-4295G>C",
"hgvs_p": null,
"transcript": "NM_001321102.2",
"protein_id": "NP_001308031.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 735,
"cds_start": null,
"cds_end": null,
"cds_length": 2208,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2462,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001321102.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.1531-4295G>C",
"hgvs_p": null,
"transcript": "ENST00000382110.6",
"protein_id": "ENSP00000371544.2",
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": 735,
"cds_start": null,
"cds_end": null,
"cds_length": 2208,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 2483,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000382110.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.1531-4295G>C",
"hgvs_p": null,
"transcript": "ENST00000935225.1",
"protein_id": "ENSP00000605284.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 735,
"cds_start": null,
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"cdna_start": null,
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"cdna_length": 3650,
"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000935225.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.1531-4295G>C",
"hgvs_p": null,
"transcript": "ENST00000935226.1",
"protein_id": "ENSP00000605285.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 735,
"cds_start": null,
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"cdna_start": null,
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"cdna_length": 2653,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000935226.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.1531-4295G>C",
"hgvs_p": null,
"transcript": "ENST00000858085.1",
"protein_id": "ENSP00000528144.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 702,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000858085.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 11,
"intron_rank": 5,
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"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.1417-4295G>C",
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"transcript": "ENST00000858082.1",
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"biotype": "protein_coding",
"feature": "ENST00000858082.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.1417-4295G>C",
"hgvs_p": null,
"transcript": "ENST00000858083.1",
"protein_id": "ENSP00000528142.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000858083.1"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 9,
"intron_rank": 3,
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"gene_symbol": "TRAPPC12",
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"hgvs_c": "c.1165-4295G>C",
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"transcript": "ENST00000858084.1",
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"biotype": "protein_coding",
"feature": "ENST00000858084.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.1165-4295G>C",
"hgvs_p": null,
"transcript": "ENST00000858089.1",
"protein_id": "ENSP00000528148.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 613,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000858089.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.1165-12271G>C",
"hgvs_p": null,
"transcript": "ENST00000935227.1",
"protein_id": "ENSP00000605286.1",
"transcript_support_level": null,
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"mane_select": null,
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},
{
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"strand": true,
"consequences": [
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],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 1,
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"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.25-4295G>C",
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"transcript": "ENST00000415624.5",
"protein_id": "ENSP00000396592.1",
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"biotype": "protein_coding",
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},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 7,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.463-4295G>C",
"hgvs_p": null,
"transcript": "ENST00000441983.5",
"protein_id": "ENSP00000409960.2",
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000441983.5"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.1417-4295G>C",
"hgvs_p": null,
"transcript": "XM_011510350.3",
"protein_id": "XP_011508652.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
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"cds_start": null,
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"cdna_start": null,
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"cdna_length": 2385,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_011510350.3"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "TRAPPC12",
"gene_hgnc_id": 24284,
"hgvs_c": "c.1417-4295G>C",
"hgvs_p": null,
"transcript": "XM_047444637.1",
"protein_id": "XP_047300593.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
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"cds_start": null,
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"cdna_start": null,
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"cdna_length": 2348,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_047444637.1"
},
{
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"canonical": false,
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