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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 21-33504401-G-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=21&pos=33504401&ref=G&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "21",
"pos": 33504401,
"ref": "G",
"alt": "C",
"effect": "intron_variant",
"transcript": "NM_000819.5",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2841+11C>G",
"hgvs_p": null,
"transcript": "NM_000819.5",
"protein_id": "NP_000810.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1010,
"cds_start": null,
"cds_end": null,
"cds_length": 3033,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000381815.9",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_000819.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2841+11C>G",
"hgvs_p": null,
"transcript": "ENST00000381815.9",
"protein_id": "ENSP00000371236.4",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1010,
"cds_start": null,
"cds_end": null,
"cds_length": 3033,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_000819.5",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000381815.9"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2841+11C>G",
"hgvs_p": null,
"transcript": "ENST00000381831.7",
"protein_id": "ENSP00000371253.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1010,
"cds_start": null,
"cds_end": null,
"cds_length": 3033,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000381831.7"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2841+11C>G",
"hgvs_p": null,
"transcript": "ENST00000381839.7",
"protein_id": "ENSP00000371261.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1010,
"cds_start": null,
"cds_end": null,
"cds_length": 3033,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000381839.7"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "n.*1924+11C>G",
"hgvs_p": null,
"transcript": "ENST00000424203.5",
"protein_id": "ENSP00000390003.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "nonsense_mediated_decay",
"feature": "ENST00000424203.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2868+11C>G",
"hgvs_p": null,
"transcript": "ENST00000880381.1",
"protein_id": "ENSP00000550440.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1019,
"cds_start": null,
"cds_end": null,
"cds_length": 3060,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000880381.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2841+11C>G",
"hgvs_p": null,
"transcript": "NM_001136005.1",
"protein_id": "NP_001129477.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1010,
"cds_start": null,
"cds_end": null,
"cds_length": 3033,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001136005.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2841+11C>G",
"hgvs_p": null,
"transcript": "NM_001136006.1",
"protein_id": "NP_001129478.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1010,
"cds_start": null,
"cds_end": null,
"cds_length": 3033,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001136006.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2841+11C>G",
"hgvs_p": null,
"transcript": "ENST00000880373.1",
"protein_id": "ENSP00000550432.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1010,
"cds_start": null,
"cds_end": null,
"cds_length": 3033,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000880373.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2841+11C>G",
"hgvs_p": null,
"transcript": "ENST00000880374.1",
"protein_id": "ENSP00000550433.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1010,
"cds_start": null,
"cds_end": null,
"cds_length": 3033,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000880374.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2841+11C>G",
"hgvs_p": null,
"transcript": "ENST00000880375.1",
"protein_id": "ENSP00000550434.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1010,
"cds_start": null,
"cds_end": null,
"cds_length": 3033,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000880375.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2841+11C>G",
"hgvs_p": null,
"transcript": "ENST00000880376.1",
"protein_id": "ENSP00000550435.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1010,
"cds_start": null,
"cds_end": null,
"cds_length": 3033,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000880376.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2841+11C>G",
"hgvs_p": null,
"transcript": "ENST00000880377.1",
"protein_id": "ENSP00000550436.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1010,
"cds_start": null,
"cds_end": null,
"cds_length": 3033,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000880377.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2838+11C>G",
"hgvs_p": null,
"transcript": "ENST00000880379.1",
"protein_id": "ENSP00000550438.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1009,
"cds_start": null,
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"cds_length": 3030,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000880379.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 21,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2838+11C>G",
"hgvs_p": null,
"transcript": "ENST00000880382.1",
"protein_id": "ENSP00000550441.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1009,
"cds_start": null,
"cds_end": null,
"cds_length": 3030,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000880382.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 20,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2772+11C>G",
"hgvs_p": null,
"transcript": "ENST00000880383.1",
"protein_id": "ENSP00000550442.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 987,
"cds_start": null,
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"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000880383.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 20,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2703+11C>G",
"hgvs_p": null,
"transcript": "ENST00000880378.1",
"protein_id": "ENSP00000550437.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 964,
"cds_start": null,
"cds_end": null,
"cds_length": 2895,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000880378.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 20,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2703+11C>G",
"hgvs_p": null,
"transcript": "ENST00000880380.1",
"protein_id": "ENSP00000550439.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 964,
"cds_start": null,
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"cds_length": 2895,
"cdna_start": null,
"cdna_end": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000880380.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 20,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2703+11C>G",
"hgvs_p": null,
"transcript": "ENST00000962328.1",
"protein_id": "ENSP00000632387.1",
"transcript_support_level": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000962328.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 20,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2676+11C>G",
"hgvs_p": null,
"transcript": "ENST00000880386.1",
"protein_id": "ENSP00000550445.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 955,
"cds_start": null,
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"cds_length": 2868,
"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000880386.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 20,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2676+11C>G",
"hgvs_p": null,
"transcript": "ENST00000935277.1",
"protein_id": "ENSP00000605336.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 955,
"cds_start": null,
"cds_end": null,
"cds_length": 2868,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000935277.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 19,
"intron_rank_end": null,
"gene_symbol": "GART",
"gene_hgnc_id": 4163,
"hgvs_c": "c.2667+11C>G",
"hgvs_p": null,
"transcript": "ENST00000880385.1",
"protein_id": "ENSP00000550444.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 952,
"cds_start": null,
"cds_end": null,
"cds_length": 2859,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000880385.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 20,
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}