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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 4-71417036-G-A (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=4&pos=71417036&ref=G&alt=A&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "4",
"pos": 71417036,
"ref": "G",
"alt": "A",
"effect": "intron_variant",
"transcript": "NM_001440629.1",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.807+19383G>A",
"hgvs_p": null,
"transcript": "NM_001098484.3",
"protein_id": "NP_001091954.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1079,
"cds_start": null,
"cds_end": null,
"cds_length": 3240,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000264485.11",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001098484.3"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.807+19383G>A",
"hgvs_p": null,
"transcript": "ENST00000264485.11",
"protein_id": "ENSP00000264485.5",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1079,
"cds_start": null,
"cds_end": null,
"cds_length": 3240,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_001098484.3",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000264485.11"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 23,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.675+19383G>A",
"hgvs_p": null,
"transcript": "NM_003759.4",
"protein_id": "NP_003750.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1035,
"cds_start": null,
"cds_end": null,
"cds_length": 3108,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": "ENST00000340595.4",
"biotype": "protein_coding",
"feature": "NM_003759.4"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 23,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.675+19383G>A",
"hgvs_p": null,
"transcript": "ENST00000340595.4",
"protein_id": "ENSP00000344272.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1035,
"cds_start": null,
"cds_end": null,
"cds_length": 3108,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": "NM_003759.4",
"biotype": "protein_coding",
"feature": "ENST00000340595.4"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 24,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.807+19383G>A",
"hgvs_p": null,
"transcript": "ENST00000351898.10",
"protein_id": "ENSP00000307349.7",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 995,
"cds_start": null,
"cds_end": null,
"cds_length": 2988,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000351898.10"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": 4,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.675+19383G>A",
"hgvs_p": null,
"transcript": "ENST00000512686.5",
"protein_id": "ENSP00000422400.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 646,
"cds_start": null,
"cds_end": null,
"cds_length": 1941,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000512686.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": 5,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "n.736+19383G>A",
"hgvs_p": null,
"transcript": "ENST00000514331.1",
"protein_id": null,
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "pseudogene",
"feature": "ENST00000514331.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.900+19383G>A",
"hgvs_p": null,
"transcript": "NM_001440629.1",
"protein_id": "NP_001427558.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1110,
"cds_start": null,
"cds_end": null,
"cds_length": 3333,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001440629.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 8,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.891+19383G>A",
"hgvs_p": null,
"transcript": "ENST00000895605.1",
"protein_id": "ENSP00000565664.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1107,
"cds_start": null,
"cds_end": null,
"cds_length": 3324,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000895605.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 25,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.807+19383G>A",
"hgvs_p": null,
"transcript": "NM_001134742.2",
"protein_id": "NP_001128214.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1094,
"cds_start": null,
"cds_end": null,
"cds_length": 3285,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001134742.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 25,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.807+19383G>A",
"hgvs_p": null,
"transcript": "ENST00000425175.5",
"protein_id": "ENSP00000393557.1",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 1094,
"cds_start": null,
"cds_end": null,
"cds_length": 3285,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000425175.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 8,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.822+19383G>A",
"hgvs_p": null,
"transcript": "NM_001440628.1",
"protein_id": "NP_001427557.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1084,
"cds_start": null,
"cds_end": null,
"cds_length": 3255,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001440628.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 8,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.807+19383G>A",
"hgvs_p": null,
"transcript": "ENST00000649996.1",
"protein_id": "ENSP00000497468.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1079,
"cds_start": null,
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"cds_length": 3240,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000649996.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.807+19383G>A",
"hgvs_p": null,
"transcript": "ENST00000895608.1",
"protein_id": "ENSP00000565667.1",
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000895608.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.807+19383G>A",
"hgvs_p": null,
"transcript": "ENST00000895609.1",
"protein_id": "ENSP00000565668.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1079,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000895609.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.807+19383G>A",
"hgvs_p": null,
"transcript": "ENST00000895610.1",
"protein_id": "ENSP00000565669.1",
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000895610.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.807+19383G>A",
"hgvs_p": null,
"transcript": "ENST00000962280.1",
"protein_id": "ENSP00000632339.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000962280.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.780+19383G>A",
"hgvs_p": null,
"transcript": "ENST00000895606.1",
"protein_id": "ENSP00000565665.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1070,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000895606.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.780+19383G>A",
"hgvs_p": null,
"transcript": "ENST00000895607.1",
"protein_id": "ENSP00000565666.1",
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"biotype": "protein_coding",
"feature": "ENST00000895607.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 10,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.903+19383G>A",
"hgvs_p": null,
"transcript": "ENST00000698522.1",
"protein_id": "ENSP00000513771.1",
"transcript_support_level": null,
"aa_start": null,
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"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000698522.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 28,
"intron_rank": 9,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.822+19383G>A",
"hgvs_p": null,
"transcript": "XM_024454268.2",
"protein_id": "XP_024310036.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1084,
"cds_start": null,
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"cds_length": 3255,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_024454268.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "SLC4A4",
"gene_hgnc_id": 11030,
"hgvs_c": "c.807+19383G>A",
"hgvs_p": null,
"transcript": "XM_024454270.2",
"protein_id": "XP_024310038.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1079,
"cds_start": null,
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"cds_length": 3240,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_024454270.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
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}
],
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}