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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 4-73104747-C-T (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=4&pos=73104747&ref=C&alt=T&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "4",
"pos": 73104747,
"ref": "C",
"alt": "T",
"effect": "intron_variant",
"transcript": "NM_032217.5",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 34,
"intron_rank": 24,
"intron_rank_end": null,
"gene_symbol": "ANKRD17",
"gene_hgnc_id": 23575,
"hgvs_c": "c.4402-2200G>A",
"hgvs_p": null,
"transcript": "NM_032217.5",
"protein_id": "NP_115593.3",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 2603,
"cds_start": null,
"cds_end": null,
"cds_length": 7812,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000358602.9",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_032217.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 34,
"intron_rank": 24,
"intron_rank_end": null,
"gene_symbol": "ANKRD17",
"gene_hgnc_id": 23575,
"hgvs_c": "c.4402-2200G>A",
"hgvs_p": null,
"transcript": "ENST00000358602.9",
"protein_id": "ENSP00000351416.4",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 2603,
"cds_start": null,
"cds_end": null,
"cds_length": 7812,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_032217.5",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000358602.9"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 34,
"intron_rank": 24,
"intron_rank_end": null,
"gene_symbol": "ANKRD17",
"gene_hgnc_id": 23575,
"hgvs_c": "c.4063-2200G>A",
"hgvs_p": null,
"transcript": "ENST00000509867.6",
"protein_id": "ENSP00000427151.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 2490,
"cds_start": null,
"cds_end": null,
"cds_length": 7473,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000509867.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 34,
"intron_rank": 24,
"intron_rank_end": null,
"gene_symbol": "ANKRD17",
"gene_hgnc_id": 23575,
"hgvs_c": "c.4051-2200G>A",
"hgvs_p": null,
"transcript": "ENST00000558247.5",
"protein_id": "ENSP00000453434.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 2486,
"cds_start": null,
"cds_end": null,
"cds_length": 7461,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000558247.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 34,
"intron_rank": 24,
"intron_rank_end": null,
"gene_symbol": "ANKRD17",
"gene_hgnc_id": 23575,
"hgvs_c": "c.4399-2200G>A",
"hgvs_p": null,
"transcript": "NM_015574.2",
"protein_id": "NP_056389.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 2602,
"cds_start": null,
"cds_end": null,
"cds_length": 7809,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_015574.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 34,
"intron_rank": 24,
"intron_rank_end": null,
"gene_symbol": "ANKRD17",
"gene_hgnc_id": 23575,
"hgvs_c": "c.4402-2200G>A",
"hgvs_p": null,
"transcript": "ENST00000914560.1",
"protein_id": "ENSP00000584619.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 2576,
"cds_start": null,
"cds_end": null,
"cds_length": 7731,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000914560.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": 24,
"intron_rank_end": null,
"gene_symbol": "ANKRD17",
"gene_hgnc_id": 23575,
"hgvs_c": "c.4402-2200G>A",
"hgvs_p": null,
"transcript": "ENST00000914561.1",
"protein_id": "ENSP00000584620.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 2537,
"cds_start": null,
"cds_end": null,
"cds_length": 7614,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000914561.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 34,
"intron_rank": 24,
"intron_rank_end": null,
"gene_symbol": "ANKRD17",
"gene_hgnc_id": 23575,
"hgvs_c": "c.4063-2200G>A",
"hgvs_p": null,
"transcript": "NM_001286771.3",
"protein_id": "NP_001273700.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 2490,
"cds_start": null,
"cds_end": null,
"cds_length": 7473,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001286771.3"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": 22,
"intron_rank_end": null,
"gene_symbol": "ANKRD17",
"gene_hgnc_id": 23575,
"hgvs_c": "c.4060-2200G>A",
"hgvs_p": null,
"transcript": "ENST00000914562.1",
"protein_id": "ENSP00000584621.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 2489,
"cds_start": null,
"cds_end": null,
"cds_length": 7470,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000914562.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": 23,
"intron_rank_end": null,
"gene_symbol": "ANKRD17",
"gene_hgnc_id": 23575,
"hgvs_c": "c.3649-2200G>A",
"hgvs_p": null,
"transcript": "NM_198889.3",
"protein_id": "NP_942592.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 2352,
"cds_start": null,
"cds_end": null,
"cds_length": 7059,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_198889.3"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 33,
"intron_rank": 23,
"intron_rank_end": null,
"gene_symbol": "ANKRD17",
"gene_hgnc_id": 23575,
"hgvs_c": "c.3649-2200G>A",
"hgvs_p": null,
"transcript": "ENST00000330838.10",
"protein_id": "ENSP00000332265.6",
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": 2352,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000330838.10"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 33,
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"gene_symbol": "ANKRD17",
"gene_hgnc_id": 23575,
"hgvs_c": "c.3646-2200G>A",
"hgvs_p": null,
"transcript": "ENST00000914559.1",
"protein_id": "ENSP00000584618.1",
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"biotype": "protein_coding",
"feature": "ENST00000914559.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 13,
"intron_rank": 12,
"intron_rank_end": null,
"gene_symbol": "ANKRD17",
"gene_hgnc_id": 23575,
"hgvs_c": "c.2503-2200G>A",
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"transcript": "ENST00000561029.1",
"protein_id": "ENSP00000453294.1",
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"cdna_start": null,
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},
{
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],
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"gene_symbol": "ANKRD17",
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"hgvs_c": "c.4402-2200G>A",
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},
{
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"strand": false,
"consequences": [
"intron_variant"
],
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"exon_count": 34,
"intron_rank": 24,
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"gene_symbol": "ANKRD17",
"gene_hgnc_id": 23575,
"hgvs_c": "c.4060-2200G>A",
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"transcript": "XM_017008011.2",
"protein_id": "XP_016863500.1",
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},
{
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],
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"gene_symbol": "ANKRD17",
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"hgvs_c": "c.3967-2200G>A",
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},
{
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"consequences": [
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],
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"intron_rank": 23,
"intron_rank_end": null,
"gene_symbol": "ANKRD17",
"gene_hgnc_id": 23575,
"hgvs_c": "c.3739-2200G>A",
"hgvs_p": null,
"transcript": "XM_047450040.1",
"protein_id": "XP_047305996.1",
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"feature": "XM_047450040.1"
},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 33,
"intron_rank": 23,
"intron_rank_end": null,
"gene_symbol": "ANKRD17",
"gene_hgnc_id": 23575,
"hgvs_c": "c.3736-2200G>A",
"hgvs_p": null,
"transcript": "XM_047450041.1",
"protein_id": "XP_047305997.1",
"transcript_support_level": null,
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},
{
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],
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"gene_symbol": "ANKRD17",
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},
{
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"strand": false,
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],
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"gene_symbol": "ANKRD17",
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},
{
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"consequences": [
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],
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"gene_symbol": "ANKRD17",
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"hgvs_c": "c.3307-2200G>A",
"hgvs_p": null,
"transcript": "XM_017008013.2",
"protein_id": "XP_016863502.1",
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"biotype": "protein_coding",
"feature": "XM_017008013.2"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 26,
"intron_rank": 24,
"intron_rank_end": null,
"gene_symbol": "ANKRD17",
"gene_hgnc_id": 23575,
"hgvs_c": "c.4402-2200G>A",
"hgvs_p": null,
"transcript": "XM_005265672.5",
"protein_id": "XP_005265729.1",
"transcript_support_level": null,
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"biotype": "protein_coding",
"feature": "XM_005265672.5"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
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],
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}