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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 4-84717462-G-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=4&pos=84717462&ref=G&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "4",
"pos": 84717462,
"ref": "G",
"alt": "C",
"effect": "intron_variant",
"transcript": "NM_014991.6",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 68,
"intron_rank": 48,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
"gene_hgnc_id": 20751,
"hgvs_c": "c.7755-446C>G",
"hgvs_p": null,
"transcript": "NM_014991.6",
"protein_id": "NP_055806.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 3526,
"cds_start": null,
"cds_end": null,
"cds_length": 10581,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000295888.9",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_014991.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 68,
"intron_rank": 48,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
"gene_hgnc_id": 20751,
"hgvs_c": "c.7755-446C>G",
"hgvs_p": null,
"transcript": "ENST00000295888.9",
"protein_id": "ENSP00000295888.4",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 3526,
"cds_start": null,
"cds_end": null,
"cds_length": 10581,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_014991.6",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000295888.9"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 57,
"intron_rank": 37,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
"gene_hgnc_id": 20751,
"hgvs_c": "c.6195-446C>G",
"hgvs_p": null,
"transcript": "ENST00000514711.2",
"protein_id": "ENSP00000424987.2",
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": 3006,
"cds_start": null,
"cds_end": null,
"cds_length": 9021,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000514711.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 70,
"intron_rank": 50,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
"gene_hgnc_id": 20751,
"hgvs_c": "c.7809-446C>G",
"hgvs_p": null,
"transcript": "XM_005262858.6",
"protein_id": "XP_005262915.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 3544,
"cds_start": null,
"cds_end": null,
"cds_length": 10635,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_005262858.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 69,
"intron_rank": 49,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
"gene_hgnc_id": 20751,
"hgvs_c": "c.7809-446C>G",
"hgvs_p": null,
"transcript": "XM_011531757.4",
"protein_id": "XP_011530059.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 3544,
"cds_start": null,
"cds_end": null,
"cds_length": 10635,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_011531757.4"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 68,
"intron_rank": 48,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
"gene_hgnc_id": 20751,
"hgvs_c": "c.7809-446C>G",
"hgvs_p": null,
"transcript": "XM_011531759.3",
"protein_id": "XP_011530061.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 3544,
"cds_start": null,
"cds_end": null,
"cds_length": 10635,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_011531759.3"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 68,
"intron_rank": 48,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
"gene_hgnc_id": 20751,
"hgvs_c": "c.7809-446C>G",
"hgvs_p": null,
"transcript": "XM_011531760.4",
"protein_id": "XP_011530062.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 3544,
"cds_start": null,
"cds_end": null,
"cds_length": 10635,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_011531760.4"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 71,
"intron_rank": 51,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
"gene_hgnc_id": 20751,
"hgvs_c": "c.7809-446C>G",
"hgvs_p": null,
"transcript": "XM_017007906.3",
"protein_id": "XP_016863395.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 3544,
"cds_start": null,
"cds_end": null,
"cds_length": 10635,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_017007906.3"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 71,
"intron_rank": 51,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
"gene_hgnc_id": 20751,
"hgvs_c": "c.7809-446C>G",
"hgvs_p": null,
"transcript": "XM_017007907.3",
"protein_id": "XP_016863396.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 3544,
"cds_start": null,
"cds_end": null,
"cds_length": 10635,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_017007907.3"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 70,
"intron_rank": 50,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
"gene_hgnc_id": 20751,
"hgvs_c": "c.7809-446C>G",
"hgvs_p": null,
"transcript": "XM_017007908.3",
"protein_id": "XP_016863397.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 3544,
"cds_start": null,
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"cds_length": 10635,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_017007908.3"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 71,
"intron_rank": 51,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
"gene_hgnc_id": 20751,
"hgvs_c": "c.7809-446C>G",
"hgvs_p": null,
"transcript": "XM_047449846.1",
"protein_id": "XP_047305802.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 3544,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "XM_047449846.1"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 71,
"intron_rank": 51,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
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"hgvs_c": "c.7809-446C>G",
"hgvs_p": null,
"transcript": "XM_047449847.1",
"protein_id": "XP_047305803.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"biotype": "protein_coding",
"feature": "XM_047449847.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 71,
"intron_rank": 51,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
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"hgvs_c": "c.7809-446C>G",
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"protein_id": "XP_047305804.1",
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"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_047449848.1"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
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"intron_rank": 51,
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"gene_symbol": "WDFY3",
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"hgvs_c": "c.7809-446C>G",
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},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 70,
"intron_rank": 50,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
"gene_hgnc_id": 20751,
"hgvs_c": "c.7809-446C>G",
"hgvs_p": null,
"transcript": "XM_047449850.1",
"protein_id": "XP_047305806.1",
"transcript_support_level": null,
"aa_start": null,
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"biotype": "protein_coding",
"feature": "XM_047449850.1"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 67,
"intron_rank": 47,
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"gene_symbol": "WDFY3",
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"hgvs_c": "c.7809-446C>G",
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"transcript": "XM_047449860.1",
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"biotype": "protein_coding",
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},
{
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"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 69,
"intron_rank": 49,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
"gene_hgnc_id": 20751,
"hgvs_c": "c.7764-446C>G",
"hgvs_p": null,
"transcript": "XM_011531761.4",
"protein_id": "XP_011530063.1",
"transcript_support_level": null,
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"cds_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "XM_011531761.4"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 68,
"intron_rank": 48,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
"gene_hgnc_id": 20751,
"hgvs_c": "c.7758-446C>G",
"hgvs_p": null,
"transcript": "XM_011531762.4",
"protein_id": "XP_011530064.1",
"transcript_support_level": null,
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"aa_end": null,
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"feature": "XM_011531762.4"
},
{
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"strand": false,
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],
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"exon_count": 67,
"intron_rank": 47,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
"gene_hgnc_id": 20751,
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},
{
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"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
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"intron_rank": 49,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
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"hgvs_c": "c.7755-446C>G",
"hgvs_p": null,
"transcript": "XM_047449851.1",
"protein_id": "XP_047305807.1",
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},
{
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"strand": false,
"consequences": [
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],
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"intron_rank": 48,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
"gene_hgnc_id": 20751,
"hgvs_c": "c.7755-446C>G",
"hgvs_p": null,
"transcript": "XM_047449852.1",
"protein_id": "XP_047305808.1",
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"aa_start": null,
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"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_047449852.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 68,
"intron_rank": 48,
"intron_rank_end": null,
"gene_symbol": "WDFY3",
"gene_hgnc_id": 20751,
"hgvs_c": "c.7725-446C>G",
"hgvs_p": null,
"transcript": "XM_011531764.4",
"protein_id": "XP_011530066.1",
"transcript_support_level": null,
"aa_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_011531764.4"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
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],
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}