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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 5-146120433-C-T (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=5&pos=146120433&ref=C&alt=T&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "5",
"pos": 146120433,
"ref": "C",
"alt": "T",
"effect": "missense_variant",
"transcript": "ENST00000394434.7",
"consequences": [
{
"aa_ref": "R",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 31,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "c.3263G>A",
"hgvs_p": "p.Arg1088Lys",
"transcript": "NM_020117.11",
"protein_id": "NP_064502.9",
"transcript_support_level": null,
"aa_start": 1088,
"aa_end": null,
"aa_length": 1176,
"cds_start": 3263,
"cds_end": null,
"cds_length": 3531,
"cdna_start": 3420,
"cdna_end": null,
"cdna_length": 4760,
"mane_select": "ENST00000394434.7",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "K",
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 31,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "c.3263G>A",
"hgvs_p": "p.Arg1088Lys",
"transcript": "ENST00000394434.7",
"protein_id": "ENSP00000377954.2",
"transcript_support_level": 1,
"aa_start": 1088,
"aa_end": null,
"aa_length": 1176,
"cds_start": 3263,
"cds_end": null,
"cds_length": 3531,
"cdna_start": 3420,
"cdna_end": null,
"cdna_length": 4760,
"mane_select": "NM_020117.11",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 31,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "c.3260G>A",
"hgvs_p": "p.Arg1087Lys",
"transcript": "ENST00000674398.1",
"protein_id": "ENSP00000501476.1",
"transcript_support_level": null,
"aa_start": 1087,
"aa_end": null,
"aa_length": 1175,
"cds_start": 3260,
"cds_end": null,
"cds_length": 3528,
"cdna_start": 3437,
"cdna_end": null,
"cdna_length": 4768,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 31,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "c.3227G>A",
"hgvs_p": "p.Arg1076Lys",
"transcript": "ENST00000674290.1",
"protein_id": "ENSP00000501435.1",
"transcript_support_level": null,
"aa_start": 1076,
"aa_end": null,
"aa_length": 1164,
"cds_start": 3227,
"cds_end": null,
"cds_length": 3495,
"cdna_start": 3394,
"cdna_end": null,
"cdna_length": 7202,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 30,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "c.3182G>A",
"hgvs_p": "p.Arg1061Lys",
"transcript": "NM_016460.4",
"protein_id": "NP_057544.2",
"transcript_support_level": null,
"aa_start": 1061,
"aa_end": null,
"aa_length": 1149,
"cds_start": 3182,
"cds_end": null,
"cds_length": 3450,
"cdna_start": 3339,
"cdna_end": null,
"cdna_length": 4679,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 30,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "c.3182G>A",
"hgvs_p": "p.Arg1061Lys",
"transcript": "ENST00000674447.1",
"protein_id": "ENSP00000501376.1",
"transcript_support_level": null,
"aa_start": 1061,
"aa_end": null,
"aa_length": 1149,
"cds_start": 3182,
"cds_end": null,
"cds_length": 3450,
"cdna_start": 3339,
"cdna_end": null,
"cdna_length": 7147,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 30,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "c.3125G>A",
"hgvs_p": "p.Arg1042Lys",
"transcript": "NM_001317964.2",
"protein_id": "NP_001304893.1",
"transcript_support_level": null,
"aa_start": 1042,
"aa_end": null,
"aa_length": 1130,
"cds_start": 3125,
"cds_end": null,
"cds_length": 3393,
"cdna_start": 3282,
"cdna_end": null,
"cdna_length": 4622,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 30,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "c.3125G>A",
"hgvs_p": "p.Arg1042Lys",
"transcript": "ENST00000674270.1",
"protein_id": "ENSP00000501365.1",
"transcript_support_level": null,
"aa_start": 1042,
"aa_end": null,
"aa_length": 1130,
"cds_start": 3125,
"cds_end": null,
"cds_length": 3393,
"cdna_start": 3282,
"cdna_end": null,
"cdna_length": 7090,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 30,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "c.3101G>A",
"hgvs_p": "p.Arg1034Lys",
"transcript": "NM_001317965.2",
"protein_id": "NP_001304894.1",
"transcript_support_level": null,
"aa_start": 1034,
"aa_end": null,
"aa_length": 1122,
"cds_start": 3101,
"cds_end": null,
"cds_length": 3369,
"cdna_start": 3301,
"cdna_end": null,
"cdna_length": 4641,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 30,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "c.3101G>A",
"hgvs_p": "p.Arg1034Lys",
"transcript": "ENST00000510191.5",
"protein_id": "ENSP00000426005.1",
"transcript_support_level": 2,
"aa_start": 1034,
"aa_end": null,
"aa_length": 1122,
"cds_start": 3101,
"cds_end": null,
"cds_length": 3369,
"cdna_start": 3274,
"cdna_end": null,
"cdna_length": 3737,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 31,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "c.3101G>A",
"hgvs_p": "p.Arg1034Lys",
"transcript": "ENST00000674174.1",
"protein_id": "ENSP00000501434.1",
"transcript_support_level": null,
"aa_start": 1034,
"aa_end": null,
"aa_length": 1122,
"cds_start": 3101,
"cds_end": null,
"cds_length": 3369,
"cdna_start": 3332,
"cdna_end": null,
"cdna_length": 7140,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 31,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "c.3098G>A",
"hgvs_p": "p.Arg1033Lys",
"transcript": "ENST00000674277.1",
"protein_id": "ENSP00000501510.1",
"transcript_support_level": null,
"aa_start": 1033,
"aa_end": null,
"aa_length": 1121,
"cds_start": 3098,
"cds_end": null,
"cds_length": 3366,
"cdna_start": 3338,
"cdna_end": null,
"cdna_length": 4669,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 29,
"exon_rank_end": null,
"exon_count": 30,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "c.2882G>A",
"hgvs_p": "p.Arg961Lys",
"transcript": "ENST00000674158.1",
"protein_id": "ENSP00000501474.1",
"transcript_support_level": null,
"aa_start": 961,
"aa_end": null,
"aa_length": 1049,
"cds_start": 2882,
"cds_end": null,
"cds_length": 3150,
"cdna_start": 3374,
"cdna_end": null,
"cdna_length": 7182,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 30,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "c.2807G>A",
"hgvs_p": "p.Arg936Lys",
"transcript": "ENST00000674191.1",
"protein_id": "ENSP00000501478.1",
"transcript_support_level": null,
"aa_start": 936,
"aa_end": null,
"aa_length": 1024,
"cds_start": 2807,
"cds_end": null,
"cds_length": 3075,
"cdna_start": 3172,
"cdna_end": null,
"cdna_length": 6980,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "R",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"missense_variant"
],
"exon_rank": 31,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "c.3101G>A",
"hgvs_p": "p.Arg1034Lys",
"transcript": "XM_011537656.4",
"protein_id": "XP_011535958.1",
"transcript_support_level": null,
"aa_start": 1034,
"aa_end": null,
"aa_length": 1122,
"cds_start": 3101,
"cds_end": null,
"cds_length": 3369,
"cdna_start": 3286,
"cdna_end": null,
"cdna_length": 4626,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 15,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "n.3693G>A",
"hgvs_p": null,
"transcript": "ENST00000504323.6",
"protein_id": null,
"transcript_support_level": 3,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
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"cdna_start": null,
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"cdna_length": 4156,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 13,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "n.6145G>A",
"hgvs_p": null,
"transcript": "ENST00000506231.6",
"protein_id": null,
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 9953,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 31,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "n.*1701G>A",
"hgvs_p": null,
"transcript": "ENST00000674170.1",
"protein_id": "ENSP00000501381.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 7331,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 13,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "n.*1067G>A",
"hgvs_p": null,
"transcript": "ENST00000674181.1",
"protein_id": "ENSP00000501475.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
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"cdna_start": null,
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"mane_select": null,
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"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 30,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "n.6050G>A",
"hgvs_p": null,
"transcript": "ENST00000674218.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
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"cdna_length": 9858,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 30,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "n.*619G>A",
"hgvs_p": null,
"transcript": "ENST00000674309.1",
"protein_id": "ENSP00000501400.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 7157,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 31,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "n.3263G>A",
"hgvs_p": null,
"transcript": "ENST00000674310.1",
"protein_id": "ENSP00000501486.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": -4,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3647,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 29,
"exon_rank_end": null,
"exon_count": 30,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "LARS1",
"gene_hgnc_id": 6512,
"hgvs_c": "n.5916G>A",
"hgvs_p": null,
"transcript": "ENST00000674383.1",
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},
{
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"canonical": false,
"protein_coding": false,
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"consequences": [
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},
{
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"strand": false,
"consequences": [
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},
{
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},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"3_prime_UTR_variant"
],
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"gene_symbol": "LARS1",
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"hgvs_c": "n.*1701G>A",
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"transcript": "ENST00000674170.1",
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},
{
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"3_prime_UTR_variant"
],
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"exon_count": 14,
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"hgvs_c": "n.*1067G>A",
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"transcript": "ENST00000674181.1",
"protein_id": "ENSP00000501475.1",
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},
{
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"3_prime_UTR_variant"
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"gene_symbol": "LARS1",
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"hgvs_c": "n.*619G>A",
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"transcript": "ENST00000674309.1",
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},
{
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"3_prime_UTR_variant"
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"gene_symbol": "LARS1",
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"transcript": "ENST00000674467.1",
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},
{
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"protein_coding": false,
"strand": true,
"consequences": [
"downstream_gene_variant"
],
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"gene_symbol": "ENSG00000251556",
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"hgvs_c": "n.*21C>T",
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"transcript": "ENST00000514002.1",
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"feature": null
}
],
"gene_symbol": "LARS1",
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"dbsnp": "rs10988",
"frequency_reference_population": 0.2747827,
"hom_count_reference_population": 64821,
"allele_count_reference_population": 443064,
"gnomad_exomes_af": 0.279989,
"gnomad_genomes_af": 0.224769,
"gnomad_exomes_ac": 408891,
"gnomad_genomes_ac": 34173,
"gnomad_exomes_homalt": 59976,
"gnomad_genomes_homalt": 4845,
"gnomad_mito_homoplasmic": null,
"gnomad_mito_heteroplasmic": null,
"computational_score_selected": 0.0032483041286468506,
"computational_prediction_selected": "Benign",
"computational_source_selected": "MetaRNN",
"splice_score_selected": 0,
"splice_prediction_selected": "Benign",
"splice_source_selected": "max_spliceai",
"revel_score": 0.092,
"revel_prediction": "Benign",
"alphamissense_score": 0.1502,
"alphamissense_prediction": null,
"bayesdelnoaf_score": -0.37,
"bayesdelnoaf_prediction": "Benign",
"phylop100way_score": 4.996,
"phylop100way_prediction": "Uncertain_significance",
"spliceai_max_score": 0,
"spliceai_max_prediction": "Benign",
"dbscsnv_ada_score": null,
"dbscsnv_ada_prediction": null,
"apogee2_score": null,
"apogee2_prediction": null,
"mitotip_score": null,
"mitotip_prediction": null,
"acmg_score": -20,
"acmg_classification": "Benign",
"acmg_criteria": "BP4_Strong,BP6_Very_Strong,BA1",
"acmg_by_gene": [
{
"score": -20,
"benign_score": 20,
"pathogenic_score": 0,
"criteria": [
"BP4_Strong",
"BP6_Very_Strong",
"BA1"
],
"verdict": "Benign",
"transcript": "ENST00000394434.7",
"gene_symbol": "LARS1",
"hgnc_id": 6512,
"effects": [
"missense_variant"
],
"inheritance_mode": "AR",
"hgvs_c": "c.3263G>A",
"hgvs_p": "p.Arg1088Lys"
},
{
"score": -20,
"benign_score": 20,
"pathogenic_score": 0,
"criteria": [
"BP4_Strong",
"BP6_Very_Strong",
"BA1"
],
"verdict": "Benign",
"transcript": "ENST00000514002.1",
"gene_symbol": "ENSG00000251556",
"hgnc_id": null,
"effects": [
"downstream_gene_variant"
],
"inheritance_mode": "",
"hgvs_c": "n.*21C>T",
"hgvs_p": null
}
],
"clinvar_disease": "not provided,not specified",
"clinvar_classification": "Benign",
"clinvar_review_status": "criteria provided, multiple submitters, no conflicts",
"clinvar_submissions_summary": "B:2",
"phenotype_combined": "not specified|not provided",
"pathogenicity_classification_combined": "Benign",
"custom_annotations": null
}
],
"message": null
}