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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 5-35695742-T-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=5&pos=35695742&ref=T&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "5",
"pos": 35695742,
"ref": "T",
"alt": "C",
"effect": "synonymous_variant",
"transcript": "ENST00000356031.8",
"consequences": [
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 37,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1983T>C",
"hgvs_p": "p.Asn661Asn",
"transcript": "NM_024867.4",
"protein_id": "NP_079143.3",
"transcript_support_level": null,
"aa_start": 661,
"aa_end": null,
"aa_length": 1822,
"cds_start": 1983,
"cds_end": null,
"cds_length": 5469,
"cdna_start": 2118,
"cdna_end": null,
"cdna_length": 5662,
"mane_select": "ENST00000356031.8",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 37,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1983T>C",
"hgvs_p": "p.Asn661Asn",
"transcript": "ENST00000356031.8",
"protein_id": "ENSP00000348314.3",
"transcript_support_level": 1,
"aa_start": 661,
"aa_end": null,
"aa_length": 1822,
"cds_start": 1983,
"cds_end": null,
"cds_length": 5469,
"cdna_start": 2118,
"cdna_end": null,
"cdna_length": 5662,
"mane_select": "NM_024867.4",
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 19,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1968T>C",
"hgvs_p": "p.Asn656Asn",
"transcript": "ENST00000509059.5",
"protein_id": "ENSP00000421593.1",
"transcript_support_level": 1,
"aa_start": 656,
"aa_end": null,
"aa_length": 943,
"cds_start": 1968,
"cds_end": null,
"cds_length": 2832,
"cdna_start": 2122,
"cdna_end": null,
"cdna_length": 4707,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 35,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1983T>C",
"hgvs_p": "p.Asn661Asn",
"transcript": "ENST00000637569.1",
"protein_id": "ENSP00000490886.1",
"transcript_support_level": 5,
"aa_start": 661,
"aa_end": null,
"aa_length": 2169,
"cds_start": 1983,
"cds_end": null,
"cds_length": 6510,
"cdna_start": 2137,
"cdna_end": null,
"cdna_length": 7350,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 37,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1968T>C",
"hgvs_p": "p.Asn656Asn",
"transcript": "ENST00000440995.6",
"protein_id": "ENSP00000412125.2",
"transcript_support_level": 5,
"aa_start": 656,
"aa_end": null,
"aa_length": 1818,
"cds_start": 1968,
"cds_end": null,
"cds_length": 5457,
"cdna_start": 1968,
"cdna_end": null,
"cdna_length": 5964,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 42,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1983T>C",
"hgvs_p": "p.Asn661Asn",
"transcript": "XM_011514135.4",
"protein_id": "XP_011512437.1",
"transcript_support_level": null,
"aa_start": 661,
"aa_end": null,
"aa_length": 2097,
"cds_start": 1983,
"cds_end": null,
"cds_length": 6294,
"cdna_start": 2118,
"cdna_end": null,
"cdna_length": 6740,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 42,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1983T>C",
"hgvs_p": "p.Asn661Asn",
"transcript": "XM_011514136.4",
"protein_id": "XP_011512438.1",
"transcript_support_level": null,
"aa_start": 661,
"aa_end": null,
"aa_length": 2096,
"cds_start": 1983,
"cds_end": null,
"cds_length": 6291,
"cdna_start": 2118,
"cdna_end": null,
"cdna_length": 6484,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 42,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1968T>C",
"hgvs_p": "p.Asn656Asn",
"transcript": "XM_011514137.4",
"protein_id": "XP_011512439.1",
"transcript_support_level": null,
"aa_start": 656,
"aa_end": null,
"aa_length": 2092,
"cds_start": 1968,
"cds_end": null,
"cds_length": 6279,
"cdna_start": 2103,
"cdna_end": null,
"cdna_length": 6725,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 42,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1983T>C",
"hgvs_p": "p.Asn661Asn",
"transcript": "XM_011514138.4",
"protein_id": "XP_011512440.1",
"transcript_support_level": null,
"aa_start": 661,
"aa_end": null,
"aa_length": 2089,
"cds_start": 1983,
"cds_end": null,
"cds_length": 6270,
"cdna_start": 2118,
"cdna_end": null,
"cdna_length": 6716,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 41,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1983T>C",
"hgvs_p": "p.Asn661Asn",
"transcript": "XM_011514139.4",
"protein_id": "XP_011512441.1",
"transcript_support_level": null,
"aa_start": 661,
"aa_end": null,
"aa_length": 2072,
"cds_start": 1983,
"cds_end": null,
"cds_length": 6219,
"cdna_start": 2118,
"cdna_end": null,
"cdna_length": 6665,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 13,
"exon_rank_end": null,
"exon_count": 41,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1812T>C",
"hgvs_p": "p.Asn604Asn",
"transcript": "XM_011514140.3",
"protein_id": "XP_011512442.1",
"transcript_support_level": null,
"aa_start": 604,
"aa_end": null,
"aa_length": 2040,
"cds_start": 1812,
"cds_end": null,
"cds_length": 6123,
"cdna_start": 1947,
"cdna_end": null,
"cdna_length": 6569,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 13,
"exon_rank_end": null,
"exon_count": 41,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1797T>C",
"hgvs_p": "p.Asn599Asn",
"transcript": "XM_017009880.3",
"protein_id": "XP_016865369.1",
"transcript_support_level": null,
"aa_start": 599,
"aa_end": null,
"aa_length": 2035,
"cds_start": 1797,
"cds_end": null,
"cds_length": 6108,
"cdna_start": 1932,
"cdna_end": null,
"cdna_length": 6554,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 12,
"exon_rank_end": null,
"exon_count": 40,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1557T>C",
"hgvs_p": "p.Asn519Asn",
"transcript": "XM_047417765.1",
"protein_id": "XP_047273721.1",
"transcript_support_level": null,
"aa_start": 519,
"aa_end": null,
"aa_length": 1955,
"cds_start": 1557,
"cds_end": null,
"cds_length": 5868,
"cdna_start": 2509,
"cdna_end": null,
"cdna_length": 7131,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 12,
"exon_rank_end": null,
"exon_count": 40,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1557T>C",
"hgvs_p": "p.Asn519Asn",
"transcript": "XM_047417766.1",
"protein_id": "XP_047273722.1",
"transcript_support_level": null,
"aa_start": 519,
"aa_end": null,
"aa_length": 1955,
"cds_start": 1557,
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"cdna_start": 3579,
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"cdna_length": 8201,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 37,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1983T>C",
"hgvs_p": "p.Asn661Asn",
"transcript": "XM_005248376.5",
"protein_id": "XP_005248433.1",
"transcript_support_level": null,
"aa_start": 661,
"aa_end": null,
"aa_length": 1823,
"cds_start": 1983,
"cds_end": null,
"cds_length": 5472,
"cdna_start": 2118,
"cdna_end": null,
"cdna_length": 5918,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 37,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1968T>C",
"hgvs_p": "p.Asn656Asn",
"transcript": "XM_005248377.5",
"protein_id": "XP_005248434.1",
"transcript_support_level": null,
"aa_start": 656,
"aa_end": null,
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"cds_start": 1968,
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"cdna_start": 2103,
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"cdna_length": 5903,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 36,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1983T>C",
"hgvs_p": "p.Asn661Asn",
"transcript": "XM_047417767.1",
"protein_id": "XP_047273723.1",
"transcript_support_level": null,
"aa_start": 661,
"aa_end": null,
"aa_length": 1797,
"cds_start": 1983,
"cds_end": null,
"cds_length": 5394,
"cdna_start": 2118,
"cdna_end": null,
"cdna_length": 5587,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 13,
"exon_rank_end": null,
"exon_count": 35,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1812T>C",
"hgvs_p": "p.Asn604Asn",
"transcript": "XM_024446219.2",
"protein_id": "XP_024301987.1",
"transcript_support_level": null,
"aa_start": 604,
"aa_end": null,
"aa_length": 1740,
"cds_start": 1812,
"cds_end": null,
"cds_length": 5223,
"cdna_start": 1947,
"cdna_end": null,
"cdna_length": 5416,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1983T>C",
"hgvs_p": "p.Asn661Asn",
"transcript": "XM_047417768.1",
"protein_id": "XP_047273724.1",
"transcript_support_level": null,
"aa_start": 661,
"aa_end": null,
"aa_length": 1537,
"cds_start": 1983,
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"cdna_start": 2118,
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"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1983T>C",
"hgvs_p": "p.Asn661Asn",
"transcript": "XM_047417769.1",
"protein_id": "XP_047273725.1",
"transcript_support_level": null,
"aa_start": 661,
"aa_end": null,
"aa_length": 1500,
"cds_start": 1983,
"cds_end": null,
"cds_length": 4503,
"cdna_start": 2118,
"cdna_end": null,
"cdna_length": 4777,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 25,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1983T>C",
"hgvs_p": "p.Asn661Asn",
"transcript": "XM_017009882.3",
"protein_id": "XP_016865371.1",
"transcript_support_level": null,
"aa_start": 661,
"aa_end": null,
"aa_length": 1185,
"cds_start": 1983,
"cds_end": null,
"cds_length": 3558,
"cdna_start": 2118,
"cdna_end": null,
"cdna_length": 3778,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"hgvs_c": "c.1983T>C",
"hgvs_p": "p.Asn661Asn",
"transcript": "XM_005248378.5",
"protein_id": "XP_005248435.1",
"transcript_support_level": null,
"aa_start": 661,
"aa_end": null,
"aa_length": 972,
"cds_start": 1983,
"cds_end": null,
"cds_length": 2919,
"cdna_start": 2118,
"cdna_end": null,
"cdna_length": 4500,
"mane_select": null,
"mane_plus": null,
"biotype": null,
"feature": null
},
{
"aa_ref": "N",
"aa_alt": "N",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 14,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SPEF2",
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"feature": null
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 7,
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"exon_count": 11,
"intron_rank": null,
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"gene_symbol": "SPEF2",
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},
{
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"protein_coding": false,
"strand": true,
"consequences": [
"non_coding_transcript_exon_variant"
],
"exon_rank": 5,
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"exon_count": 9,
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"gene_symbol": "SPEF2",
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"hgvs_c": "n.835T>C",
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"transcript": "ENST00000504054.1",
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"cdna_length": 1500,
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"feature": null
},
{
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"protein_coding": false,
"strand": true,
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"non_coding_transcript_exon_variant"
],
"exon_rank": 14,
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"gene_symbol": "SPEF2",
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"hgvs_c": "n.2118T>C",
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"transcript": "XR_925655.3",
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},
{
"aa_ref": null,
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"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
],
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"gene_symbol": "ENSG00000248969",
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},
{
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"intron_variant"
],
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"gene_symbol": "ENSG00000248969",
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"hgvs_c": "n.133+2216A>G",
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"transcript": "ENST00000736912.1",
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}
],
"gene_symbol": "SPEF2",
"gene_hgnc_id": 26293,
"dbsnp": "rs78576797",
"frequency_reference_population": 0.022712812,
"hom_count_reference_population": 706,
"allele_count_reference_population": 36554,
"gnomad_exomes_af": 0.0228094,
"gnomad_genomes_af": 0.0217891,
"gnomad_exomes_ac": 33235,
"gnomad_genomes_ac": 3319,
"gnomad_exomes_homalt": 637,
"gnomad_genomes_homalt": 69,
"gnomad_mito_homoplasmic": null,
"gnomad_mito_heteroplasmic": null,
"computational_score_selected": -0.8999999761581421,
"computational_prediction_selected": "Benign",
"computational_source_selected": "BayesDel_noAF",
"splice_score_selected": 0,
"splice_prediction_selected": "Benign",
"splice_source_selected": "max_spliceai",
"revel_score": null,
"revel_prediction": null,
"alphamissense_score": null,
"alphamissense_prediction": null,
"bayesdelnoaf_score": -0.9,
"bayesdelnoaf_prediction": "Benign",
"phylop100way_score": -0.86,
"phylop100way_prediction": "Benign",
"spliceai_max_score": 0,
"spliceai_max_prediction": "Benign",
"dbscsnv_ada_score": null,
"dbscsnv_ada_prediction": null,
"apogee2_score": null,
"apogee2_prediction": null,
"mitotip_score": null,
"mitotip_prediction": null,
"acmg_score": -21,
"acmg_classification": "Benign",
"acmg_criteria": "BP4_Strong,BP6_Very_Strong,BP7,BA1",
"acmg_by_gene": [
{
"score": -21,
"benign_score": 21,
"pathogenic_score": 0,
"criteria": [
"BP4_Strong",
"BP6_Very_Strong",
"BP7",
"BA1"
],
"verdict": "Benign",
"transcript": "ENST00000356031.8",
"gene_symbol": "SPEF2",
"hgnc_id": 26293,
"effects": [
"synonymous_variant"
],
"inheritance_mode": "AR,AD",
"hgvs_c": "c.1983T>C",
"hgvs_p": "p.Asn661Asn"
},
{
"score": -20,
"benign_score": 20,
"pathogenic_score": 0,
"criteria": [
"BP4_Strong",
"BP6_Very_Strong",
"BA1"
],
"verdict": "Benign",
"transcript": "ENST00000510433.1",
"gene_symbol": "ENSG00000248969",
"hgnc_id": null,
"effects": [
"intron_variant"
],
"inheritance_mode": "",
"hgvs_c": "n.251+2216A>G",
"hgvs_p": null
}
],
"clinvar_disease": "not provided,not specified",
"clinvar_classification": "Benign",
"clinvar_review_status": "criteria provided, multiple submitters, no conflicts",
"clinvar_submissions_summary": "B:3",
"phenotype_combined": "not specified|not provided",
"pathogenicity_classification_combined": "Benign",
"custom_annotations": null
}
],
"message": null
}