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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 6-18192322-G-T (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=6&pos=18192322&ref=G&alt=T&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "6",
"pos": 18192322,
"ref": "G",
"alt": "T",
"effect": "intron_variant",
"transcript": "NM_001439117.1",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 10,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.969+941G>T",
"hgvs_p": null,
"transcript": "NM_001364614.2",
"protein_id": "NP_001351543.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 822,
"cds_start": null,
"cds_end": null,
"cds_length": 2469,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000650836.2",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001364614.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 10,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.969+941G>T",
"hgvs_p": null,
"transcript": "ENST00000650836.2",
"protein_id": "ENSP00000499208.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 822,
"cds_start": null,
"cds_end": null,
"cds_length": 2469,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_001364614.2",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000650836.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.-18-22685G>T",
"hgvs_p": null,
"transcript": "ENST00000546309.6",
"protein_id": "ENSP00000442670.1",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 113,
"cds_start": null,
"cds_end": null,
"cds_length": 342,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000546309.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 23,
"intron_rank": 11,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.996+941G>T",
"hgvs_p": null,
"transcript": "NM_001439117.1",
"protein_id": "NP_001426046.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 832,
"cds_start": null,
"cds_end": null,
"cds_length": 2499,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001439117.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 23,
"intron_rank": 11,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.996+941G>T",
"hgvs_p": null,
"transcript": "NM_001439118.1",
"protein_id": "NP_001426047.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 831,
"cds_start": null,
"cds_end": null,
"cds_length": 2496,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001439118.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 10,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.969+941G>T",
"hgvs_p": null,
"transcript": "NM_001439119.1",
"protein_id": "NP_001426048.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 823,
"cds_start": null,
"cds_end": null,
"cds_length": 2472,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001439119.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 22,
"intron_rank": 10,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.969+941G>T",
"hgvs_p": null,
"transcript": "ENST00000449850.2",
"protein_id": "ENSP00000405669.2",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 823,
"cds_start": null,
"cds_end": null,
"cds_length": 2472,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000449850.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 9,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.969+941G>T",
"hgvs_p": null,
"transcript": "ENST00000897550.1",
"protein_id": "ENSP00000567609.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 823,
"cds_start": null,
"cds_end": null,
"cds_length": 2472,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000897550.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 9,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.969+941G>T",
"hgvs_p": null,
"transcript": "NM_001439130.1",
"protein_id": "NP_001426059.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 822,
"cds_start": null,
"cds_end": null,
"cds_length": 2469,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001439130.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 9,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.969+941G>T",
"hgvs_p": null,
"transcript": "ENST00000897548.1",
"protein_id": "ENSP00000567607.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 822,
"cds_start": null,
"cds_end": null,
"cds_length": 2469,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000897548.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 23,
"intron_rank": 11,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.969+941G>T",
"hgvs_p": null,
"transcript": "ENST00000897549.1",
"protein_id": "ENSP00000567608.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 822,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000897549.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 22,
"intron_rank": 10,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.969+941G>T",
"hgvs_p": null,
"transcript": "ENST00000897551.1",
"protein_id": "ENSP00000567610.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 822,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000897551.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 9,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.879+941G>T",
"hgvs_p": null,
"transcript": "NM_001439120.1",
"protein_id": "NP_001426049.1",
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"aa_start": null,
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"aa_length": 793,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001439120.1"
},
{
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"protein_coding": true,
"strand": true,
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],
"exon_rank": null,
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"exon_count": 21,
"intron_rank": 9,
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"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.879+941G>T",
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"transcript": "NM_001439121.1",
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001439121.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 8,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.574-4735G>T",
"hgvs_p": null,
"transcript": "NM_001439122.1",
"protein_id": "NP_001426051.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "NM_001439122.1"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 20,
"intron_rank": 8,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
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"hgvs_c": "c.574-4735G>T",
"hgvs_p": null,
"transcript": "NM_001439123.1",
"protein_id": "NP_001426052.1",
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "NM_001439123.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 19,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.535-4735G>T",
"hgvs_p": null,
"transcript": "NM_001439124.1",
"protein_id": "NP_001426053.1",
"transcript_support_level": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "NM_001439124.1"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 19,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.535-4735G>T",
"hgvs_p": null,
"transcript": "NM_001439125.1",
"protein_id": "NP_001426054.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"biotype": "protein_coding",
"feature": "NM_001439125.1"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 18,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.484-4735G>T",
"hgvs_p": null,
"transcript": "NM_001439126.1",
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"feature": "NM_001439126.1"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 19,
"intron_rank": 7,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
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"hgvs_c": "c.484-4735G>T",
"hgvs_p": null,
"transcript": "NM_001439127.1",
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"feature": "NM_001439127.1"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.445-4735G>T",
"hgvs_p": null,
"transcript": "NM_001439128.1",
"protein_id": "NP_001426057.1",
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"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001439128.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 18,
"intron_rank": 6,
"intron_rank_end": null,
"gene_symbol": "KDM1B",
"gene_hgnc_id": 21577,
"hgvs_c": "c.445-4735G>T",
"hgvs_p": null,
"transcript": "NM_001439129.1",
"protein_id": "NP_001426058.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 647,
"cds_start": null,
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"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001439129.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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