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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 6-28341813-T-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=6&pos=28341813&ref=T&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "6",
"pos": 28341813,
"ref": "T",
"alt": "C",
"effect": "intron_variant",
"transcript": "NM_145909.3",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-370-21A>G",
"hgvs_p": null,
"transcript": "ENST00000396838.6",
"protein_id": "ENSP00000380050.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": null,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3176,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000396838.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-235-18A>G",
"hgvs_p": null,
"transcript": "NM_001135215.1",
"protein_id": "NP_001128687.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": null,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3554,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001135215.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-370-21A>G",
"hgvs_p": null,
"transcript": "NM_145909.3",
"protein_id": "NP_665916.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": null,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3185,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_145909.3"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 8,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-235-18A>G",
"hgvs_p": null,
"transcript": "ENST00000414429.5",
"protein_id": "ENSP00000390076.1",
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": null,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3551,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000414429.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-249-4870A>G",
"hgvs_p": null,
"transcript": "ENST00000881652.1",
"protein_id": "ENSP00000551711.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": null,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3314,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000881652.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-95-12035A>G",
"hgvs_p": null,
"transcript": "ENST00000881653.1",
"protein_id": "ENSP00000551712.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": null,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3130,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000881653.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-32+12049A>G",
"hgvs_p": null,
"transcript": "ENST00000881654.1",
"protein_id": "ENSP00000551713.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": null,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3033,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000881654.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 7,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-323-3920A>G",
"hgvs_p": null,
"transcript": "ENST00000881655.1",
"protein_id": "ENSP00000551714.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": null,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3140,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000881655.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-145-18A>G",
"hgvs_p": null,
"transcript": "ENST00000881656.1",
"protein_id": "ENSP00000551715.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": null,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 3075,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000881656.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-50+12049A>G",
"hgvs_p": null,
"transcript": "ENST00000881657.1",
"protein_id": "ENSP00000551716.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": null,
"cds_end": null,
"cds_length": 1221,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 1942,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000881657.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-235-18A>G",
"hgvs_p": null,
"transcript": "ENST00000962705.1",
"protein_id": "ENSP00000632764.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 406,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000962705.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 7,
"intron_rank": 1,
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"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-330-18A>G",
"hgvs_p": null,
"transcript": "ENST00000962706.1",
"protein_id": "ENSP00000632765.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000962706.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 6,
"intron_rank": 1,
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"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-387-3920A>G",
"hgvs_p": null,
"transcript": "ENST00000962707.1",
"protein_id": "ENSP00000632766.1",
"transcript_support_level": null,
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"cds_start": null,
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"cdna_start": null,
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"biotype": "protein_coding",
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},
{
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"strand": false,
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],
"exon_rank": null,
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"exon_count": 5,
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"gene_symbol": "ZSCAN31",
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"hgvs_c": "c.-81-18A>G",
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"transcript": "ENST00000962708.1",
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},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 6,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-249-4870A>G",
"hgvs_p": null,
"transcript": "ENST00000962709.1",
"protein_id": "ENSP00000632768.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"biotype": "protein_coding",
"feature": "ENST00000962709.1"
},
{
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"strand": false,
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],
"exon_rank": null,
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"exon_count": 7,
"intron_rank": 1,
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"gene_symbol": "ZSCAN31",
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"hgvs_c": "c.-373-18A>G",
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"transcript": "ENST00000962710.1",
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},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 5,
"intron_rank": 1,
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"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-1135-3920A>G",
"hgvs_p": null,
"transcript": "ENST00000962711.1",
"protein_id": "ENSP00000632770.1",
"transcript_support_level": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000962711.1"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
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],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-344-3920A>G",
"hgvs_p": null,
"transcript": "ENST00000962712.1",
"protein_id": "ENSP00000632771.1",
"transcript_support_level": null,
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},
{
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"consequences": [
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],
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"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
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"hgvs_c": "c.-203-4870A>G",
"hgvs_p": null,
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"feature": "ENST00000962713.1"
},
{
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"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
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"hgvs_c": "c.-249-4870A>G",
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"transcript": "ENST00000446222.5",
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},
{
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"consequences": [
"intron_variant"
],
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"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.33+12049A>G",
"hgvs_p": null,
"transcript": "ENST00000426434.1",
"protein_id": "ENSP00000398680.1",
"transcript_support_level": 4,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000426434.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ZSCAN31",
"gene_hgnc_id": 14097,
"hgvs_c": "c.-185-4870A>G",
"hgvs_p": null,
"transcript": "ENST00000434036.5",
"protein_id": "ENSP00000416225.1",
"transcript_support_level": 3,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"cdna_length": 584,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000434036.5"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
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