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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 6-31701518-A-T (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=6&pos=31701518&ref=A&alt=T&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "6",
"pos": 31701518,
"ref": "A",
"alt": "T",
"effect": "intron_variant",
"transcript": "NM_021160.3",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ABHD16A",
"gene_hgnc_id": 13921,
"hgvs_c": "c.190-178T>A",
"hgvs_p": null,
"transcript": "NM_021160.3",
"protein_id": "NP_066983.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 558,
"cds_start": null,
"cds_end": null,
"cds_length": 1677,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000395952.8",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_021160.3"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ABHD16A",
"gene_hgnc_id": 13921,
"hgvs_c": "c.190-178T>A",
"hgvs_p": null,
"transcript": "ENST00000395952.8",
"protein_id": "ENSP00000379282.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 558,
"cds_start": null,
"cds_end": null,
"cds_length": 1677,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_021160.3",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000395952.8"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 21,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ABHD16A",
"gene_hgnc_id": 13921,
"hgvs_c": "c.190-178T>A",
"hgvs_p": null,
"transcript": "ENST00000875899.1",
"protein_id": "ENSP00000545958.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 572,
"cds_start": null,
"cds_end": null,
"cds_length": 1719,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000875899.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ABHD16A",
"gene_hgnc_id": 13921,
"hgvs_c": "c.190-178T>A",
"hgvs_p": null,
"transcript": "ENST00000875898.1",
"protein_id": "ENSP00000545957.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 570,
"cds_start": null,
"cds_end": null,
"cds_length": 1713,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000875898.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ABHD16A",
"gene_hgnc_id": 13921,
"hgvs_c": "c.190-178T>A",
"hgvs_p": null,
"transcript": "ENST00000875900.1",
"protein_id": "ENSP00000545959.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 568,
"cds_start": null,
"cds_end": null,
"cds_length": 1707,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000875900.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ABHD16A",
"gene_hgnc_id": 13921,
"hgvs_c": "c.190-178T>A",
"hgvs_p": null,
"transcript": "ENST00000959096.1",
"protein_id": "ENSP00000629155.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 568,
"cds_start": null,
"cds_end": null,
"cds_length": 1707,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000959096.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ABHD16A",
"gene_hgnc_id": 13921,
"hgvs_c": "c.190-178T>A",
"hgvs_p": null,
"transcript": "ENST00000959095.1",
"protein_id": "ENSP00000629154.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 567,
"cds_start": null,
"cds_end": null,
"cds_length": 1704,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000959095.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ABHD16A",
"gene_hgnc_id": 13921,
"hgvs_c": "c.190-178T>A",
"hgvs_p": null,
"transcript": "ENST00000875896.1",
"protein_id": "ENSP00000545955.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 556,
"cds_start": null,
"cds_end": null,
"cds_length": 1671,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000875896.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 20,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "ABHD16A",
"gene_hgnc_id": 13921,
"hgvs_c": "c.190-178T>A",
"hgvs_p": null,
"transcript": "ENST00000875905.1",
"protein_id": "ENSP00000545964.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 554,
"cds_start": null,
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"cds_length": 1665,
"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000875905.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 20,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ABHD16A",
"gene_hgnc_id": 13921,
"hgvs_c": "c.133-178T>A",
"hgvs_p": null,
"transcript": "ENST00000959098.1",
"protein_id": "ENSP00000629157.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000959098.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 20,
"intron_rank": 2,
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"gene_symbol": "ABHD16A",
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"hgvs_c": "c.190-178T>A",
"hgvs_p": null,
"transcript": "ENST00000959100.1",
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"cds_start": null,
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"cdna_start": null,
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},
{
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],
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"gene_symbol": "ABHD16A",
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},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 19,
"intron_rank": 1,
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"gene_symbol": "ABHD16A",
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"hgvs_c": "c.133-178T>A",
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"feature": "ENST00000875897.1"
},
{
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],
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"gene_symbol": "ABHD16A",
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},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"gene_symbol": "ABHD16A",
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"hgvs_c": "c.190-178T>A",
"hgvs_p": null,
"transcript": "ENST00000875901.1",
"protein_id": "ENSP00000545960.1",
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},
{
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],
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"gene_symbol": "ABHD16A",
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"hgvs_c": "c.158-490T>A",
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"transcript": "NM_001177515.2",
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},
{
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"strand": false,
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],
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"intron_rank": 1,
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"gene_symbol": "ABHD16A",
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"hgvs_c": "c.158-490T>A",
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"transcript": "ENST00000440843.2",
"protein_id": "ENSP00000410347.2",
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"feature": "ENST00000440843.2"
},
{
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],
"exon_rank": null,
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"intron_rank": 2,
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"gene_symbol": "ABHD16A",
"gene_hgnc_id": 13921,
"hgvs_c": "c.190-178T>A",
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"transcript": "ENST00000959099.1",
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},
{
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],
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"gene_symbol": "ABHD16A",
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},
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],
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},
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],
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"biotype": "protein_coding",
"feature": "ENST00000875902.1"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 17,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "ABHD16A",
"gene_hgnc_id": 13921,
"hgvs_c": "c.133-178T>A",
"hgvs_p": null,
"transcript": "ENST00000959097.1",
"protein_id": "ENSP00000629156.1",
"transcript_support_level": null,
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"biotype": "protein_coding",
"feature": "ENST00000959097.1"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
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"exon_count": 17,
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}
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}