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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 6-41559960-G-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=6&pos=41559960&ref=G&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "6",
"pos": 41559960,
"ref": "G",
"alt": "C",
"effect": "intron_variant",
"transcript": "NM_001012426.2",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FOXP4",
"gene_hgnc_id": 20842,
"hgvs_c": "c.-16-5785G>C",
"hgvs_p": null,
"transcript": "NM_001012426.2",
"protein_id": "NP_001012426.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 680,
"cds_start": null,
"cds_end": null,
"cds_length": 2043,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000307972.10",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001012426.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FOXP4",
"gene_hgnc_id": 20842,
"hgvs_c": "c.-16-5785G>C",
"hgvs_p": null,
"transcript": "ENST00000307972.10",
"protein_id": "ENSP00000309823.4",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 680,
"cds_start": null,
"cds_end": null,
"cds_length": 2043,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_001012426.2",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000307972.10"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FOXP4",
"gene_hgnc_id": 20842,
"hgvs_c": "c.-16-5785G>C",
"hgvs_p": null,
"transcript": "ENST00000373057.7",
"protein_id": "ENSP00000362148.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 678,
"cds_start": null,
"cds_end": null,
"cds_length": 2037,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000373057.7"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FOXP4",
"gene_hgnc_id": 20842,
"hgvs_c": "c.-16-5785G>C",
"hgvs_p": null,
"transcript": "ENST00000373063.7",
"protein_id": "ENSP00000362154.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 667,
"cds_start": null,
"cds_end": null,
"cds_length": 2004,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000373063.7"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FOXP4",
"gene_hgnc_id": 20842,
"hgvs_c": "c.-16-5785G>C",
"hgvs_p": null,
"transcript": "ENST00000958402.1",
"protein_id": "ENSP00000628461.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 712,
"cds_start": null,
"cds_end": null,
"cds_length": 2139,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000958402.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FOXP4",
"gene_hgnc_id": 20842,
"hgvs_c": "c.-16-5785G>C",
"hgvs_p": null,
"transcript": "ENST00000937782.1",
"protein_id": "ENSP00000607841.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 706,
"cds_start": null,
"cds_end": null,
"cds_length": 2121,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000937782.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FOXP4",
"gene_hgnc_id": 20842,
"hgvs_c": "c.-16-5785G>C",
"hgvs_p": null,
"transcript": "ENST00000892085.1",
"protein_id": "ENSP00000562144.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 692,
"cds_start": null,
"cds_end": null,
"cds_length": 2079,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000892085.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FOXP4",
"gene_hgnc_id": 20842,
"hgvs_c": "c.-16-5785G>C",
"hgvs_p": null,
"transcript": "ENST00000937784.1",
"protein_id": "ENSP00000607843.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 687,
"cds_start": null,
"cds_end": null,
"cds_length": 2064,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000937784.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 18,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "FOXP4",
"gene_hgnc_id": 20842,
"hgvs_c": "c.-16-5785G>C",
"hgvs_p": null,
"transcript": "ENST00000704756.1",
"protein_id": "ENSP00000516024.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 680,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000704756.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FOXP4",
"gene_hgnc_id": 20842,
"hgvs_c": "c.-16-5785G>C",
"hgvs_p": null,
"transcript": "ENST00000937779.1",
"protein_id": "ENSP00000607838.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 679,
"cds_start": null,
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"cds_length": 2040,
"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000937779.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 17,
"intron_rank": 1,
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"gene_symbol": "FOXP4",
"gene_hgnc_id": 20842,
"hgvs_c": "c.-16-5785G>C",
"hgvs_p": null,
"transcript": "ENST00000937783.1",
"protein_id": "ENSP00000607842.1",
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"cds_start": null,
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},
{
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],
"exon_rank": null,
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"gene_symbol": "FOXP4",
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"hgvs_c": "c.-16-5785G>C",
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"transcript": "NM_001012427.2",
"protein_id": "NP_001012427.1",
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"biotype": "protein_coding",
"feature": "NM_001012427.2"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 17,
"intron_rank": 1,
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"gene_symbol": "FOXP4",
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"hgvs_c": "c.-16-5785G>C",
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"transcript": "ENST00000937778.1",
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},
{
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],
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"gene_symbol": "FOXP4",
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},
{
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"protein_coding": true,
"strand": true,
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"intron_variant"
],
"exon_rank": null,
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"intron_rank": 1,
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"gene_symbol": "FOXP4",
"gene_hgnc_id": 20842,
"hgvs_c": "c.-16-5785G>C",
"hgvs_p": null,
"transcript": "NM_001405824.1",
"protein_id": "NP_001392753.1",
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},
{
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],
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"gene_symbol": "FOXP4",
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"hgvs_c": "c.-16-5785G>C",
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"transcript": "ENST00000409208.5",
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},
{
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],
"exon_rank": null,
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"intron_rank": 1,
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"gene_symbol": "FOXP4",
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"hgvs_c": "c.-16-5785G>C",
"hgvs_p": null,
"transcript": "NM_138457.3",
"protein_id": "NP_612466.1",
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},
{
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"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 17,
"intron_rank": 1,
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"gene_symbol": "FOXP4",
"gene_hgnc_id": 20842,
"hgvs_c": "c.-16-5785G>C",
"hgvs_p": null,
"transcript": "ENST00000937774.1",
"protein_id": "ENSP00000607833.1",
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},
{
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],
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"gene_symbol": "FOXP4",
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"hgvs_c": "c.-16-5785G>C",
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"transcript": "NM_001405825.1",
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},
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"strand": true,
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],
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"intron_rank": 1,
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"gene_symbol": "FOXP4",
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},
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"strand": true,
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],
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"gene_symbol": "FOXP4",
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"transcript": "ENST00000937777.1",
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"biotype": "protein_coding",
"feature": "ENST00000937777.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FOXP4",
"gene_hgnc_id": 20842,
"hgvs_c": "c.-16-5785G>C",
"hgvs_p": null,
"transcript": "NM_001405826.1",
"protein_id": "NP_001392755.1",
"transcript_support_level": null,
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"aa_length": 636,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001405826.1"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 16,
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}