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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 7-28974579-G-T (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=7&pos=28974579&ref=G&alt=T&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "7",
"pos": 28974579,
"ref": "G",
"alt": "T",
"effect": "intron_variant",
"transcript": "ENST00000749297.1",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 3,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CPVL-AS2",
"gene_hgnc_id": 56138,
"hgvs_c": "n.295+15530G>T",
"hgvs_p": null,
"transcript": "ENST00000749297.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 608,
"mane_select": null,
"mane_plus": null,
"biotype": "pseudogene",
"feature": "ENST00000749297.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 3,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CPVL-AS2",
"gene_hgnc_id": 56138,
"hgvs_c": "n.474+15530G>T",
"hgvs_p": null,
"transcript": "ENST00000749298.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 794,
"mane_select": null,
"mane_plus": null,
"biotype": "pseudogene",
"feature": "ENST00000749298.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 3,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CPVL-AS2",
"gene_hgnc_id": 56138,
"hgvs_c": "n.198+15530G>T",
"hgvs_p": null,
"transcript": "ENST00000749299.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 474,
"mane_select": null,
"mane_plus": null,
"biotype": "pseudogene",
"feature": "ENST00000749299.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CPVL-AS2",
"gene_hgnc_id": 56138,
"hgvs_c": "n.196+15530G>T",
"hgvs_p": null,
"transcript": "ENST00000749300.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 571,
"mane_select": null,
"mane_plus": null,
"biotype": "pseudogene",
"feature": "ENST00000749300.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 3,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "CPVL-AS2",
"gene_hgnc_id": 56138,
"hgvs_c": "n.76+17742G>T",
"hgvs_p": null,
"transcript": "ENST00000749301.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 480,
"mane_select": null,
"mane_plus": null,
"biotype": "pseudogene",
"feature": "ENST00000749301.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 3,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CPVL-AS2",
"gene_hgnc_id": 56138,
"hgvs_c": "n.173+15530G>T",
"hgvs_p": null,
"transcript": "ENST00000749302.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 493,
"mane_select": null,
"mane_plus": null,
"biotype": "pseudogene",
"feature": "ENST00000749302.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "CPVL-AS2",
"gene_hgnc_id": 56138,
"hgvs_c": "n.560+15530G>T",
"hgvs_p": null,
"transcript": "ENST00000749303.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
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"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 833,
"mane_select": null,
"mane_plus": null,
"biotype": "pseudogene",
"feature": "ENST00000749303.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": 3,
"intron_rank_end": null,
"gene_symbol": "CPVL-AS2",
"gene_hgnc_id": 56138,
"hgvs_c": "n.569+15530G>T",
"hgvs_p": null,
"transcript": "ENST00000749304.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 889,
"mane_select": null,
"mane_plus": null,
"biotype": "pseudogene",
"feature": "ENST00000749304.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 3,
"intron_rank": 2,
"intron_rank_end": null,
"gene_symbol": "CPVL-AS2",
"gene_hgnc_id": 56138,
"hgvs_c": "n.159+15530G>T",
"hgvs_p": null,
"transcript": "ENST00000749305.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": 389,
"mane_select": null,
"mane_plus": null,
"biotype": "pseudogene",
"feature": "ENST00000749305.1"
},
{
"aa_ref": null,
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"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 4,
"intron_rank": 3,
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"gene_symbol": "CPVL-AS2",
"gene_hgnc_id": 56138,
"hgvs_c": "n.230+13949G>T",
"hgvs_p": null,
"transcript": "ENST00000749306.1",
"protein_id": null,
"transcript_support_level": null,
"aa_start": null,
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"aa_length": null,
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"cdna_start": null,
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"cdna_length": 546,
"mane_select": null,
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"biotype": "pseudogene",
"feature": "ENST00000749306.1"
},
{
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"canonical": false,
"protein_coding": false,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 3,
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"gene_symbol": "CPVL-AS2",
"gene_hgnc_id": 56138,
"hgvs_c": "n.494+15530G>T",
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"transcript": "ENST00000749307.1",
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},
{
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"strand": true,
"consequences": [
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],
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},
{
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"strand": true,
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],
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"gene_symbol": "CPVL-AS2",
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"hgvs_c": "n.389+15530G>T",
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},
{
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"strand": true,
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],
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"gene_symbol": "CPVL-AS2",
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},
{
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],
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},
{
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],
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"gene_symbol": "CPVL-AS2",
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"hgvs_c": "n.334+15530G>T",
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},
{
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],
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"hgvs_c": "n.279+15530G>T",
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},
{
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],
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"gene_symbol": "CPVL-AS2",
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"hgvs_c": "n.162+15530G>T",
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},
{
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],
"exon_rank": null,
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"exon_count": 4,
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"hgvs_c": "n.278+15530G>T",
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},
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],
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},
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],
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},
{
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"strand": true,
"consequences": [
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],
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"intron_rank": 2,
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"gene_symbol": "CPVL-AS2",
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"hgvs_c": "n.179+15530G>T",
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"mane_select": null,
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"biotype": "pseudogene",
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},
{
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"protein_coding": false,
"strand": true,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 3,
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"gene_symbol": "CPVL-AS2",
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"hgvs_c": "n.168+15530G>T",
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}
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}