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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 7-47401695-G-T (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=7&pos=47401695&ref=G&alt=T&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "7",
"pos": 47401695,
"ref": "G",
"alt": "T",
"effect": "intron_variant",
"transcript": "NM_001410877.1",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 13,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.724-781C>A",
"hgvs_p": null,
"transcript": "NM_022748.12",
"protein_id": "NP_073585.8",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1445,
"cds_start": null,
"cds_end": null,
"cds_length": 4338,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000311160.14",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_022748.12"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 13,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.724-781C>A",
"hgvs_p": null,
"transcript": "ENST00000311160.14",
"protein_id": "ENSP00000312143.9",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1445,
"cds_start": null,
"cds_end": null,
"cds_length": 4338,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_022748.12",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000311160.14"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 15,
"intron_rank": 14,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "n.*33-781C>A",
"hgvs_p": null,
"transcript": "ENST00000442536.6",
"protein_id": "ENSP00000389285.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": null,
"cds_start": null,
"cds_end": null,
"cds_length": null,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "nonsense_mediated_decay",
"feature": "ENST00000442536.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 13,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.1066-781C>A",
"hgvs_p": null,
"transcript": "NM_001410877.1",
"protein_id": "NP_001397806.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1559,
"cds_start": null,
"cds_end": null,
"cds_length": 4680,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001410877.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 13,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.1066-781C>A",
"hgvs_p": null,
"transcript": "ENST00000705350.1",
"protein_id": "ENSP00000516118.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1559,
"cds_start": null,
"cds_end": null,
"cds_length": 4680,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000705350.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 13,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.1033-781C>A",
"hgvs_p": null,
"transcript": "NM_001410878.1",
"protein_id": "NP_001397807.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1548,
"cds_start": null,
"cds_end": null,
"cds_length": 4647,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001410878.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 13,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.1033-781C>A",
"hgvs_p": null,
"transcript": "ENST00000457718.6",
"protein_id": "ENSP00000414358.2",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 1548,
"cds_start": null,
"cds_end": null,
"cds_length": 4647,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000457718.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 13,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.991-781C>A",
"hgvs_p": null,
"transcript": "ENST00000450444.6",
"protein_id": "ENSP00000396914.2",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 1534,
"cds_start": null,
"cds_end": null,
"cds_length": 4605,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000450444.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": 14,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.724-781C>A",
"hgvs_p": null,
"transcript": "ENST00000887086.1",
"protein_id": "ENSP00000557145.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1445,
"cds_start": null,
"cds_end": null,
"cds_length": 4338,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000887086.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 29,
"intron_rank": 11,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.724-781C>A",
"hgvs_p": null,
"transcript": "ENST00000887087.1",
"protein_id": "ENSP00000557146.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1445,
"cds_start": null,
"cds_end": null,
"cds_length": 4338,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000887087.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 28,
"intron_rank": 10,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.724-781C>A",
"hgvs_p": null,
"transcript": "ENST00000887088.1",
"protein_id": "ENSP00000557147.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1445,
"cds_start": null,
"cds_end": null,
"cds_length": 4338,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000887088.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 30,
"intron_rank": 12,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.724-781C>A",
"hgvs_p": null,
"transcript": "ENST00000939401.1",
"protein_id": "ENSP00000609460.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1445,
"cds_start": null,
"cds_end": null,
"cds_length": 4338,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000939401.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 13,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.724-781C>A",
"hgvs_p": null,
"transcript": "ENST00000939402.1",
"protein_id": "ENSP00000609461.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1445,
"cds_start": null,
"cds_end": null,
"cds_length": 4338,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000939402.1"
},
{
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"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": 14,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.724-781C>A",
"hgvs_p": null,
"transcript": "ENST00000947274.1",
"protein_id": "ENSP00000617333.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000947274.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": 15,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.1114-781C>A",
"hgvs_p": null,
"transcript": "XM_047420723.1",
"protein_id": "XP_047276679.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1575,
"cds_start": null,
"cds_end": null,
"cds_length": 4728,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_047420723.1"
},
{
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"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 33,
"intron_rank": 15,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.1114-781C>A",
"hgvs_p": null,
"transcript": "XM_047420724.1",
"protein_id": "XP_047276680.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_047420724.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": 14,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.1072-781C>A",
"hgvs_p": null,
"transcript": "XM_047420725.1",
"protein_id": "XP_047276681.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1561,
"cds_start": null,
"cds_end": null,
"cds_length": 4686,
"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_047420725.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 30,
"intron_rank": 12,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.1033-781C>A",
"hgvs_p": null,
"transcript": "XM_017012537.2",
"protein_id": "XP_016868026.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1548,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_017012537.2"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 30,
"intron_rank": 12,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.1027-781C>A",
"hgvs_p": null,
"transcript": "XM_047420726.1",
"protein_id": "XP_047276682.1",
"transcript_support_level": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_047420726.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 32,
"intron_rank": 14,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.1000-781C>A",
"hgvs_p": null,
"transcript": "XM_047420728.1",
"protein_id": "XP_047276684.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "XM_047420728.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 30,
"intron_rank": 12,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.994-781C>A",
"hgvs_p": null,
"transcript": "XM_047420729.1",
"protein_id": "XP_047276685.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1535,
"cds_start": null,
"cds_end": null,
"cds_length": 4608,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_047420729.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 31,
"intron_rank": 13,
"intron_rank_end": null,
"gene_symbol": "TNS3",
"gene_hgnc_id": 21616,
"hgvs_c": "c.991-781C>A",
"hgvs_p": null,
"transcript": "XM_011515478.3",
"protein_id": "XP_011513780.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1534,
"cds_start": null,
"cds_end": null,
"cds_length": 4605,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_011515478.3"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
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