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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 7-74338680-C-T (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=7&pos=74338680&ref=C&alt=T&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "7",
"pos": 74338680,
"ref": "C",
"alt": "T",
"effect": "synonymous_variant",
"transcript": "NM_003388.5",
"consequences": [
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "NM_003388.5",
"protein_id": "NP_003379.4",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 1046,
"cds_start": 354,
"cds_end": null,
"cds_length": 3141,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000223398.11",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_003388.5"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000223398.11",
"protein_id": "ENSP00000223398.6",
"transcript_support_level": 5,
"aa_start": 118,
"aa_end": null,
"aa_length": 1046,
"cds_start": 354,
"cds_end": null,
"cds_length": 3141,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_003388.5",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000223398.11"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000361545.9",
"protein_id": "ENSP00000355151.5",
"transcript_support_level": 1,
"aa_start": 118,
"aa_end": null,
"aa_length": 1011,
"cds_start": 354,
"cds_end": null,
"cds_length": 3036,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000361545.9"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 18,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000884300.1",
"protein_id": "ENSP00000554359.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 1080,
"cds_start": 354,
"cds_end": null,
"cds_length": 3243,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000884300.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 18,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000941416.1",
"protein_id": "ENSP00000611475.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 1065,
"cds_start": 354,
"cds_end": null,
"cds_length": 3198,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000941416.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000884301.1",
"protein_id": "ENSP00000554360.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 1061,
"cds_start": 354,
"cds_end": null,
"cds_length": 3186,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000884301.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000930626.1",
"protein_id": "ENSP00000600685.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 1048,
"cds_start": 354,
"cds_end": null,
"cds_length": 3147,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000930626.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000941417.1",
"protein_id": "ENSP00000611476.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 1026,
"cds_start": 354,
"cds_end": null,
"cds_length": 3081,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000941417.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000941415.1",
"protein_id": "ENSP00000611474.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 1024,
"cds_start": 354,
"cds_end": null,
"cds_length": 3075,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000941415.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000930628.1",
"protein_id": "ENSP00000600687.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 1014,
"cds_start": 354,
"cds_end": null,
"cds_length": 3045,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000930628.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000941421.1",
"protein_id": "ENSP00000611480.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 1013,
"cds_start": 354,
"cds_end": null,
"cds_length": 3042,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000941421.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "NM_032421.3",
"protein_id": "NP_115797.2",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 1011,
"cds_start": 354,
"cds_end": null,
"cds_length": 3036,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_032421.3"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000884298.1",
"protein_id": "ENSP00000554357.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 1011,
"cds_start": 354,
"cds_end": null,
"cds_length": 3036,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000884298.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 5,
"exon_rank_end": null,
"exon_count": 18,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000884299.1",
"protein_id": "ENSP00000554358.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 1011,
"cds_start": 354,
"cds_end": null,
"cds_length": 3036,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000884299.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000930627.1",
"protein_id": "ENSP00000600686.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 1011,
"cds_start": 354,
"cds_end": null,
"cds_length": 3036,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000930627.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000941414.1",
"protein_id": "ENSP00000611473.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 1011,
"cds_start": 354,
"cds_end": null,
"cds_length": 3036,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000941414.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 4,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000941423.1",
"protein_id": "ENSP00000611482.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 1011,
"cds_start": 354,
"cds_end": null,
"cds_length": 3036,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000941423.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000930629.1",
"protein_id": "ENSP00000600688.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 1010,
"cds_start": 354,
"cds_end": null,
"cds_length": 3033,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000930629.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 17,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000941419.1",
"protein_id": "ENSP00000611478.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 988,
"cds_start": 354,
"cds_end": null,
"cds_length": 2967,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000941419.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000930630.1",
"protein_id": "ENSP00000600689.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 984,
"cds_start": 354,
"cds_end": null,
"cds_length": 2955,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000930630.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 16,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000941422.1",
"protein_id": "ENSP00000611481.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 975,
"cds_start": 354,
"cds_end": null,
"cds_length": 2928,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000941422.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000941420.1",
"protein_id": "ENSP00000611479.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 956,
"cds_start": 354,
"cds_end": null,
"cds_length": 2871,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000941420.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "ENST00000941418.1",
"protein_id": "ENSP00000611477.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 839,
"cds_start": 354,
"cds_end": null,
"cds_length": 2520,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000941418.1"
},
{
"aa_ref": "G",
"aa_alt": "G",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 3,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly",
"transcript": "XM_047420800.1",
"protein_id": "XP_047276756.1",
"transcript_support_level": null,
"aa_start": 118,
"aa_end": null,
"aa_length": 868,
"cds_start": 354,
"cds_end": null,
"cds_length": 2607,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "XM_047420800.1"
}
],
"gene_symbol": "CLIP2",
"gene_hgnc_id": 2586,
"dbsnp": "rs782724514",
"frequency_reference_population": null,
"hom_count_reference_population": 0,
"allele_count_reference_population": 0,
"gnomad_exomes_af": 0,
"gnomad_genomes_af": null,
"gnomad_exomes_ac": 0,
"gnomad_genomes_ac": null,
"gnomad_exomes_homalt": 0,
"gnomad_genomes_homalt": null,
"gnomad_mito_homoplasmic": null,
"gnomad_mito_heteroplasmic": null,
"computational_score_selected": -0.4699999988079071,
"computational_prediction_selected": "Benign",
"computational_source_selected": "BayesDel_noAF",
"splice_score_selected": 0.019999999552965164,
"splice_prediction_selected": "Benign",
"splice_source_selected": "max_spliceai",
"revel_score": null,
"revel_prediction": null,
"alphamissense_score": null,
"alphamissense_prediction": null,
"bayesdelnoaf_score": -0.47,
"bayesdelnoaf_prediction": "Benign",
"phylop100way_score": -0.007,
"phylop100way_prediction": "Benign",
"spliceai_max_score": 0.02,
"spliceai_max_prediction": "Benign",
"dbscsnv_ada_score": null,
"dbscsnv_ada_prediction": null,
"apogee2_score": null,
"apogee2_prediction": null,
"mitotip_score": null,
"mitotip_prediction": null,
"acmg_score": -5,
"acmg_classification": "Likely_benign",
"acmg_criteria": "PM2,BP4_Strong,BP6_Moderate,BP7",
"acmg_by_gene": [
{
"score": -5,
"benign_score": 7,
"pathogenic_score": 2,
"criteria": [
"PM2",
"BP4_Strong",
"BP6_Moderate",
"BP7"
],
"verdict": "Likely_benign",
"transcript": "NM_003388.5",
"gene_symbol": "CLIP2",
"hgnc_id": 2586,
"effects": [
"synonymous_variant"
],
"inheritance_mode": "AD",
"hgvs_c": "c.354C>T",
"hgvs_p": "p.Gly118Gly"
}
],
"clinvar_disease": "not provided",
"clinvar_classification": "Likely benign",
"clinvar_review_status": "criteria provided, single submitter",
"clinvar_submissions_summary": "LB:1",
"phenotype_combined": "not provided",
"pathogenicity_classification_combined": "Likely benign",
"custom_annotations": null
}
],
"message": null
}