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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 8-97713742-G-A (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=8&pos=97713742&ref=G&alt=A&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "8",
"pos": 97713742,
"ref": "G",
"alt": "A",
"effect": "synonymous_variant",
"transcript": "NM_001363137.1",
"consequences": [
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 9,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1353G>A",
"hgvs_p": "p.Lys451Lys",
"transcript": "NM_178812.4",
"protein_id": "NP_848927.2",
"transcript_support_level": null,
"aa_start": 451,
"aa_end": null,
"aa_length": 582,
"cds_start": 1353,
"cds_end": null,
"cds_length": 1749,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000336273.8",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_178812.4"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 9,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1353G>A",
"hgvs_p": "p.Lys451Lys",
"transcript": "ENST00000336273.8",
"protein_id": "ENSP00000338235.3",
"transcript_support_level": 1,
"aa_start": 451,
"aa_end": null,
"aa_length": 582,
"cds_start": 1353,
"cds_end": null,
"cds_length": 1749,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_178812.4",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000336273.8"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 10,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1443G>A",
"hgvs_p": "p.Lys481Lys",
"transcript": "NM_001363137.1",
"protein_id": "NP_001350066.1",
"transcript_support_level": null,
"aa_start": 481,
"aa_end": null,
"aa_length": 612,
"cds_start": 1443,
"cds_end": null,
"cds_length": 1839,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001363137.1"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 10,
"exon_rank_end": null,
"exon_count": 13,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1443G>A",
"hgvs_p": "p.Lys481Lys",
"transcript": "ENST00000887774.1",
"protein_id": "ENSP00000557833.1",
"transcript_support_level": null,
"aa_start": 481,
"aa_end": null,
"aa_length": 612,
"cds_start": 1443,
"cds_end": null,
"cds_length": 1839,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000887774.1"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 9,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1344G>A",
"hgvs_p": "p.Lys448Lys",
"transcript": "ENST00000915586.1",
"protein_id": "ENSP00000585645.1",
"transcript_support_level": null,
"aa_start": 448,
"aa_end": null,
"aa_length": 579,
"cds_start": 1344,
"cds_end": null,
"cds_length": 1740,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000915586.1"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 9,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1344G>A",
"hgvs_p": "p.Lys448Lys",
"transcript": "ENST00000953194.1",
"protein_id": "ENSP00000623253.1",
"transcript_support_level": null,
"aa_start": 448,
"aa_end": null,
"aa_length": 579,
"cds_start": 1344,
"cds_end": null,
"cds_length": 1740,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953194.1"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 10,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1443G>A",
"hgvs_p": "p.Lys481Lys",
"transcript": "ENST00000915591.1",
"protein_id": "ENSP00000585650.1",
"transcript_support_level": null,
"aa_start": 481,
"aa_end": null,
"aa_length": 565,
"cds_start": 1443,
"cds_end": null,
"cds_length": 1698,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000915591.1"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1287G>A",
"hgvs_p": "p.Lys429Lys",
"transcript": "NM_001363136.1",
"protein_id": "NP_001350065.1",
"transcript_support_level": null,
"aa_start": 429,
"aa_end": null,
"aa_length": 560,
"cds_start": 1287,
"cds_end": null,
"cds_length": 1683,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001363136.1"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1278G>A",
"hgvs_p": "p.Lys426Lys",
"transcript": "ENST00000953193.1",
"protein_id": "ENSP00000623252.1",
"transcript_support_level": null,
"aa_start": 426,
"aa_end": null,
"aa_length": 557,
"cds_start": 1278,
"cds_end": null,
"cds_length": 1674,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953193.1"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1254G>A",
"hgvs_p": "p.Lys418Lys",
"transcript": "NM_001363138.1",
"protein_id": "NP_001350067.1",
"transcript_support_level": null,
"aa_start": 418,
"aa_end": null,
"aa_length": 549,
"cds_start": 1254,
"cds_end": null,
"cds_length": 1650,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001363138.1"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1251G>A",
"hgvs_p": "p.Lys417Lys",
"transcript": "ENST00000887773.1",
"protein_id": "ENSP00000557832.1",
"transcript_support_level": null,
"aa_start": 417,
"aa_end": null,
"aa_length": 548,
"cds_start": 1251,
"cds_end": null,
"cds_length": 1647,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000887773.1"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1245G>A",
"hgvs_p": "p.Lys415Lys",
"transcript": "ENST00000915589.1",
"protein_id": "ENSP00000585648.1",
"transcript_support_level": null,
"aa_start": 415,
"aa_end": null,
"aa_length": 546,
"cds_start": 1245,
"cds_end": null,
"cds_length": 1641,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000915589.1"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 9,
"exon_rank_end": null,
"exon_count": 12,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1203G>A",
"hgvs_p": "p.Lys401Lys",
"transcript": "ENST00000915587.1",
"protein_id": "ENSP00000585646.1",
"transcript_support_level": null,
"aa_start": 401,
"aa_end": null,
"aa_length": 532,
"cds_start": 1203,
"cds_end": null,
"cds_length": 1599,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000915587.1"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1200G>A",
"hgvs_p": "p.Lys400Lys",
"transcript": "ENST00000953192.1",
"protein_id": "ENSP00000623251.1",
"transcript_support_level": null,
"aa_start": 400,
"aa_end": null,
"aa_length": 531,
"cds_start": 1200,
"cds_end": null,
"cds_length": 1596,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953192.1"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1188G>A",
"hgvs_p": "p.Lys396Lys",
"transcript": "NM_001363139.1",
"protein_id": "NP_001350068.1",
"transcript_support_level": null,
"aa_start": 396,
"aa_end": null,
"aa_length": 527,
"cds_start": 1188,
"cds_end": null,
"cds_length": 1584,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001363139.1"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1185G>A",
"hgvs_p": "p.Lys395Lys",
"transcript": "ENST00000519934.5",
"protein_id": "ENSP00000428168.1",
"transcript_support_level": 5,
"aa_start": 395,
"aa_end": null,
"aa_length": 526,
"cds_start": 1185,
"cds_end": null,
"cds_length": 1581,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000519934.5"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1176G>A",
"hgvs_p": "p.Lys392Lys",
"transcript": "ENST00000915593.1",
"protein_id": "ENSP00000585652.1",
"transcript_support_level": null,
"aa_start": 392,
"aa_end": null,
"aa_length": 523,
"cds_start": 1176,
"cds_end": null,
"cds_length": 1572,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000915593.1"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1152G>A",
"hgvs_p": "p.Lys384Lys",
"transcript": "ENST00000915588.1",
"protein_id": "ENSP00000585647.1",
"transcript_support_level": null,
"aa_start": 384,
"aa_end": null,
"aa_length": 515,
"cds_start": 1152,
"cds_end": null,
"cds_length": 1548,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000915588.1"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1254G>A",
"hgvs_p": "p.Lys418Lys",
"transcript": "ENST00000887775.1",
"protein_id": "ENSP00000557834.1",
"transcript_support_level": null,
"aa_start": 418,
"aa_end": null,
"aa_length": 502,
"cds_start": 1254,
"cds_end": null,
"cds_length": 1509,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000887775.1"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 7,
"exon_rank_end": null,
"exon_count": 10,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1110G>A",
"hgvs_p": "p.Lys370Lys",
"transcript": "ENST00000953189.1",
"protein_id": "ENSP00000623248.1",
"transcript_support_level": null,
"aa_start": 370,
"aa_end": null,
"aa_length": 501,
"cds_start": 1110,
"cds_end": null,
"cds_length": 1506,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953189.1"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 8,
"exon_rank_end": null,
"exon_count": 11,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1104G>A",
"hgvs_p": "p.Lys368Lys",
"transcript": "ENST00000953191.1",
"protein_id": "ENSP00000623250.1",
"transcript_support_level": null,
"aa_start": 368,
"aa_end": null,
"aa_length": 499,
"cds_start": 1104,
"cds_end": null,
"cds_length": 1500,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000953191.1"
},
{
"aa_ref": "K",
"aa_alt": "K",
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"synonymous_variant"
],
"exon_rank": 6,
"exon_rank_end": null,
"exon_count": 9,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "MTDH",
"gene_hgnc_id": 29608,
"hgvs_c": "c.1011G>A",
"hgvs_p": "p.Lys337Lys",
"transcript": "ENST00000953190.1",
"protein_id": "ENSP00000623249.1",
"transcript_support_level": null,
"aa_start": 337,
"aa_end": null,
"aa_length": 468,
"cds_start": 1011,
"cds_end": null,
"cds_length": 1407,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
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}
],
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}