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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 9-113220936-T-C (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=9&pos=113220936&ref=T&alt=C&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "9",
"pos": 113220936,
"ref": "T",
"alt": "C",
"effect": "intron_variant",
"transcript": "NM_015258.2",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 28,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FKBP15",
"gene_hgnc_id": 23397,
"hgvs_c": "c.53+255A>G",
"hgvs_p": null,
"transcript": "NM_015258.2",
"protein_id": "NP_056073.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1219,
"cds_start": null,
"cds_end": null,
"cds_length": 3660,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000238256.8",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_015258.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 28,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FKBP15",
"gene_hgnc_id": 23397,
"hgvs_c": "c.53+255A>G",
"hgvs_p": null,
"transcript": "ENST00000238256.8",
"protein_id": "ENSP00000238256.3",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1219,
"cds_start": null,
"cds_end": null,
"cds_length": 3660,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_015258.2",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000238256.8"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 28,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FKBP15",
"gene_hgnc_id": 23397,
"hgvs_c": "c.53+255A>G",
"hgvs_p": null,
"transcript": "ENST00000446284.6",
"protein_id": "ENSP00000416158.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1219,
"cds_start": null,
"cds_end": null,
"cds_length": 3660,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000446284.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 14,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FKBP15",
"gene_hgnc_id": 23397,
"hgvs_c": "c.53+255A>G",
"hgvs_p": null,
"transcript": "ENST00000414250.2",
"protein_id": "ENSP00000415733.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 472,
"cds_start": null,
"cds_end": null,
"cds_length": 1419,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000414250.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 28,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FKBP15",
"gene_hgnc_id": 23397,
"hgvs_c": "c.-163-49A>G",
"hgvs_p": null,
"transcript": "ENST00000693271.1",
"protein_id": "ENSP00000508580.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1256,
"cds_start": null,
"cds_end": null,
"cds_length": 3771,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000693271.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 28,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FKBP15",
"gene_hgnc_id": 23397,
"hgvs_c": "c.53+255A>G",
"hgvs_p": null,
"transcript": "ENST00000852798.1",
"protein_id": "ENSP00000522857.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1209,
"cds_start": null,
"cds_end": null,
"cds_length": 3630,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000852798.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 29,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FKBP15",
"gene_hgnc_id": 23397,
"hgvs_c": "c.-163-49A>G",
"hgvs_p": null,
"transcript": "ENST00000687395.1",
"protein_id": "ENSP00000509797.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1203,
"cds_start": null,
"cds_end": null,
"cds_length": 3612,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000687395.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FKBP15",
"gene_hgnc_id": 23397,
"hgvs_c": "c.53+255A>G",
"hgvs_p": null,
"transcript": "ENST00000947249.1",
"protein_id": "ENSP00000617308.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1194,
"cds_start": null,
"cds_end": null,
"cds_length": 3585,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000947249.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FKBP15",
"gene_hgnc_id": 23397,
"hgvs_c": "c.53+255A>G",
"hgvs_p": null,
"transcript": "ENST00000689059.1",
"protein_id": "ENSP00000508739.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1173,
"cds_start": null,
"cds_end": null,
"cds_length": 3522,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000689059.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FKBP15",
"gene_hgnc_id": 23397,
"hgvs_c": "c.53+255A>G",
"hgvs_p": null,
"transcript": "ENST00000937401.1",
"protein_id": "ENSP00000607460.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1170,
"cds_start": null,
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"cds_length": 3513,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000937401.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FKBP15",
"gene_hgnc_id": 23397,
"hgvs_c": "c.53+255A>G",
"hgvs_p": null,
"transcript": "ENST00000852799.1",
"protein_id": "ENSP00000522858.1",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cds_length": 3486,
"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000852799.1"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 25,
"intron_rank": 1,
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"gene_symbol": "FKBP15",
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"hgvs_c": "c.53+255A>G",
"hgvs_p": null,
"transcript": "ENST00000937400.1",
"protein_id": "ENSP00000607459.1",
"transcript_support_level": null,
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"cds_start": null,
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"cdna_start": null,
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"biotype": "protein_coding",
"feature": "ENST00000937400.1"
},
{
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"protein_coding": true,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 28,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FKBP15",
"gene_hgnc_id": 23397,
"hgvs_c": "c.53+255A>G",
"hgvs_p": null,
"transcript": "XM_006717018.3",
"protein_id": "XP_006717081.1",
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"cds_start": null,
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"cdna_start": null,
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"biotype": "protein_coding",
"feature": "XM_006717018.3"
},
{
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"gene_symbol": "FKBP15",
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"hgvs_c": "c.-36+255A>G",
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"transcript": "XM_006717019.2",
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},
{
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"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"exon_count": 3,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FKBP15",
"gene_hgnc_id": 23397,
"hgvs_c": "n.89+255A>G",
"hgvs_p": null,
"transcript": "ENST00000462889.1",
"protein_id": null,
"transcript_support_level": 3,
"aa_start": null,
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"aa_length": null,
"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "retained_intron",
"feature": "ENST00000462889.1"
},
{
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"protein_coding": false,
"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 4,
"intron_rank": 1,
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"gene_symbol": "FKBP15",
"gene_hgnc_id": 23397,
"hgvs_c": "n.113+255A>G",
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"transcript": "ENST00000493847.2",
"protein_id": null,
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"biotype": "retained_intron",
"feature": "ENST00000493847.2"
},
{
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"canonical": false,
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"strand": false,
"consequences": [
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],
"exon_rank": null,
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"exon_count": 26,
"intron_rank": 1,
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"gene_symbol": "FKBP15",
"gene_hgnc_id": 23397,
"hgvs_c": "n.53+255A>G",
"hgvs_p": null,
"transcript": "ENST00000685068.1",
"protein_id": "ENSP00000510494.1",
"transcript_support_level": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "nonsense_mediated_decay",
"feature": "ENST00000685068.1"
},
{
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"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FKBP15",
"gene_hgnc_id": 23397,
"hgvs_c": "n.53+255A>G",
"hgvs_p": null,
"transcript": "ENST00000685945.1",
"protein_id": "ENSP00000510324.1",
"transcript_support_level": null,
"aa_start": null,
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"biotype": "nonsense_mediated_decay",
"feature": "ENST00000685945.1"
},
{
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"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"intron_rank": 1,
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"gene_symbol": "FKBP15",
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"hgvs_c": "n.53+255A>G",
"hgvs_p": null,
"transcript": "ENST00000686727.1",
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},
{
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"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
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"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FKBP15",
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"hgvs_c": "n.208+255A>G",
"hgvs_p": null,
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"protein_id": null,
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"biotype": "retained_intron",
"feature": "ENST00000686828.1"
},
{
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"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
],
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"intron_rank": 1,
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"gene_symbol": "FKBP15",
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"transcript": "ENST00000688113.1",
"protein_id": "ENSP00000508769.1",
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"mane_select": null,
"mane_plus": null,
"biotype": "nonsense_mediated_decay",
"feature": "ENST00000688113.1"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 28,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "FKBP15",
"gene_hgnc_id": 23397,
"hgvs_c": "n.53+255A>G",
"hgvs_p": null,
"transcript": "ENST00000688949.1",
"protein_id": "ENSP00000509717.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
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"cds_start": null,
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"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "nonsense_mediated_decay",
"feature": "ENST00000688949.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": false,
"strand": false,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 25,
"intron_rank": 1,
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{
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}
],
"message": null
}