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GeneBe API Showcase
This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.
API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.
Documentation & Advanced Usage
• Complete API documentation:docs.genebe.net/docs/api/overview/
• Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/
• Python client for pandas:pypi.org/project/genebe/
• Java CLI for VCF files:github.com/pstawinski/genebe-cli
• All tools documented at:docs.genebe.net
API Request Examples for Variant: 9-128276221-C-T (hg38)
Bash / cURL Example
bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=9&pos=128276221&ref=C&alt=T&genome=hg38&allGenes=true"API Response
json
{
"variants": [
{
"chr": "9",
"pos": 128276221,
"ref": "C",
"alt": "T",
"effect": "intron_variant",
"transcript": "NM_001379267.1",
"consequences": [
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "SWI5",
"gene_hgnc_id": 31412,
"hgvs_c": "c.90-366C>T",
"hgvs_p": null,
"transcript": "NM_001379267.1",
"protein_id": "NP_001366196.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 179,
"cds_start": null,
"cds_end": null,
"cds_length": 540,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001379267.1"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 6,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "SWI5",
"gene_hgnc_id": 31412,
"hgvs_c": "c.57-486C>T",
"hgvs_p": null,
"transcript": "ENST00000372898.6",
"protein_id": "ENSP00000361989.2",
"transcript_support_level": 5,
"aa_start": null,
"aa_end": null,
"aa_length": 144,
"cds_start": null,
"cds_end": null,
"cds_length": 435,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000372898.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "SWI5",
"gene_hgnc_id": 31412,
"hgvs_c": "c.90-486C>T",
"hgvs_p": null,
"transcript": "NM_001318092.2",
"protein_id": "NP_001305021.1",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 139,
"cds_start": null,
"cds_end": null,
"cds_length": 420,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001318092.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"intron_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": 1,
"intron_rank_end": null,
"gene_symbol": "SWI5",
"gene_hgnc_id": 31412,
"hgvs_c": "c.90-486C>T",
"hgvs_p": null,
"transcript": "ENST00000495313.5",
"protein_id": "ENSP00000419719.2",
"transcript_support_level": 3,
"aa_start": null,
"aa_end": null,
"aa_length": 139,
"cds_start": null,
"cds_end": null,
"cds_length": 420,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000495313.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"upstream_gene_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "GOLGA2",
"gene_hgnc_id": 4425,
"hgvs_c": "c.-245G>A",
"hgvs_p": null,
"transcript": "NM_001366244.2",
"protein_id": "NP_001353173.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1029,
"cds_start": null,
"cds_end": null,
"cds_length": 3090,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000611957.5",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001366244.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"upstream_gene_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "GOLGA2",
"gene_hgnc_id": 4425,
"hgvs_c": "c.-245G>A",
"hgvs_p": null,
"transcript": "ENST00000611957.5",
"protein_id": "ENSP00000478799.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1029,
"cds_start": null,
"cds_end": null,
"cds_length": 3090,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_001366244.2",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000611957.5"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"upstream_gene_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SWI5",
"gene_hgnc_id": 31412,
"hgvs_c": "c.-120C>T",
"hgvs_p": null,
"transcript": "NM_001318089.2",
"protein_id": "NP_001305018.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 130,
"cds_start": null,
"cds_end": null,
"cds_length": 393,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "ENST00000418976.3",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001318089.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": true,
"protein_coding": true,
"strand": true,
"consequences": [
"upstream_gene_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SWI5",
"gene_hgnc_id": 31412,
"hgvs_c": "c.-120C>T",
"hgvs_p": null,
"transcript": "ENST00000418976.3",
"protein_id": "ENSP00000411469.3",
"transcript_support_level": 2,
"aa_start": null,
"aa_end": null,
"aa_length": 130,
"cds_start": null,
"cds_end": null,
"cds_length": 393,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": "NM_001318089.2",
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000418976.3"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"upstream_gene_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "GOLGA2",
"gene_hgnc_id": 4425,
"hgvs_c": "c.-245G>A",
"hgvs_p": null,
"transcript": "ENST00000421699.8",
"protein_id": "ENSP00000416097.4",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 1002,
"cds_start": null,
"cds_end": null,
"cds_length": 3009,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000421699.8"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"upstream_gene_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 5,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SWI5",
"gene_hgnc_id": 31412,
"hgvs_c": "c.-120C>T",
"hgvs_p": null,
"transcript": "ENST00000608796.6",
"protein_id": "ENSP00000476650.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 170,
"cds_start": null,
"cds_end": null,
"cds_length": 513,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000608796.6"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"upstream_gene_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 4,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "SWI5",
"gene_hgnc_id": 31412,
"hgvs_c": "c.-120C>T",
"hgvs_p": null,
"transcript": "ENST00000419867.7",
"protein_id": "ENSP00000477295.2",
"transcript_support_level": 1,
"aa_start": null,
"aa_end": null,
"aa_length": 151,
"cds_start": null,
"cds_end": null,
"cds_length": 456,
"cdna_start": null,
"cdna_end": null,
"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000419867.7"
},
{
"aa_ref": null,
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"upstream_gene_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "GOLGA2",
"gene_hgnc_id": 4425,
"hgvs_c": "c.-245G>A",
"hgvs_p": null,
"transcript": "NM_001389695.2",
"protein_id": "NP_001376624.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1024,
"cds_start": null,
"cds_end": null,
"cds_length": 3075,
"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001389695.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"upstream_gene_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 27,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "GOLGA2",
"gene_hgnc_id": 4425,
"hgvs_c": "c.-245G>A",
"hgvs_p": null,
"transcript": "ENST00000964637.1",
"protein_id": "ENSP00000634696.1",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 1024,
"cds_start": null,
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"cds_length": 3075,
"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "ENST00000964637.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"upstream_gene_variant"
],
"exon_rank": null,
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"exon_count": 27,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "GOLGA2",
"gene_hgnc_id": 4425,
"hgvs_c": "c.-245G>A",
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"transcript": "NM_001389696.2",
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "NM_001389696.2"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"upstream_gene_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "GOLGA2",
"gene_hgnc_id": 4425,
"hgvs_c": "c.-245G>A",
"hgvs_p": null,
"transcript": "NM_001366246.2",
"protein_id": "NP_001353175.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 1002,
"cds_start": null,
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"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001366246.2"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"upstream_gene_variant"
],
"exon_rank": null,
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"exon_count": 26,
"intron_rank": null,
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"gene_symbol": "GOLGA2",
"gene_hgnc_id": 4425,
"hgvs_c": "c.-245G>A",
"hgvs_p": null,
"transcript": "NM_004486.6",
"protein_id": "NP_004477.5",
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "NM_004486.6"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
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],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "GOLGA2",
"gene_hgnc_id": 4425,
"hgvs_c": "c.-245G>A",
"hgvs_p": null,
"transcript": "ENST00000687179.1",
"protein_id": "ENSP00000510790.1",
"transcript_support_level": null,
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"cdna_start": null,
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"mane_select": null,
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"biotype": "protein_coding",
"feature": "ENST00000687179.1"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"upstream_gene_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "GOLGA2",
"gene_hgnc_id": 4425,
"hgvs_c": "c.-245G>A",
"hgvs_p": null,
"transcript": "NM_001389697.2",
"protein_id": "NP_001376626.2",
"transcript_support_level": null,
"aa_start": null,
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"aa_length": 998,
"cds_start": null,
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"cdna_start": null,
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"biotype": "protein_coding",
"feature": "NM_001389697.2"
},
{
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"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"upstream_gene_variant"
],
"exon_rank": null,
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"exon_count": 26,
"intron_rank": null,
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"gene_symbol": "GOLGA2",
"gene_hgnc_id": 4425,
"hgvs_c": "c.-245G>A",
"hgvs_p": null,
"transcript": "ENST00000450617.8",
"protein_id": "ENSP00000409271.4",
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"feature": "ENST00000450617.8"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"upstream_gene_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 26,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "GOLGA2",
"gene_hgnc_id": 4425,
"hgvs_c": "c.-245G>A",
"hgvs_p": null,
"transcript": "NM_001389698.2",
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"biotype": "protein_coding",
"feature": "NM_001389698.2"
},
{
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"protein_coding": true,
"strand": true,
"consequences": [
"upstream_gene_variant"
],
"exon_rank": null,
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"exon_count": 25,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "GOLGA2",
"gene_hgnc_id": 4425,
"hgvs_c": "c.-245G>A",
"hgvs_p": null,
"transcript": "NM_001389699.2",
"protein_id": "NP_001376628.2",
"transcript_support_level": null,
"aa_start": null,
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"cds_start": null,
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"cdna_start": null,
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"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001389699.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"upstream_gene_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 25,
"intron_rank": null,
"intron_rank_end": null,
"gene_symbol": "GOLGA2",
"gene_hgnc_id": 4425,
"hgvs_c": "c.-245G>A",
"hgvs_p": null,
"transcript": "NM_001389700.2",
"protein_id": "NP_001376629.2",
"transcript_support_level": null,
"aa_start": null,
"aa_end": null,
"aa_length": 989,
"cds_start": null,
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"cds_length": 2970,
"cdna_start": null,
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"cdna_length": null,
"mane_select": null,
"mane_plus": null,
"biotype": "protein_coding",
"feature": "NM_001389700.2"
},
{
"aa_ref": null,
"aa_alt": null,
"canonical": false,
"protein_coding": true,
"strand": true,
"consequences": [
"upstream_gene_variant"
],
"exon_rank": null,
"exon_rank_end": null,
"exon_count": 25,
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}