← Back to variant description

GeneBe API Showcase

This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.

API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.

Documentation & Advanced Usage

Complete API documentation:docs.genebe.net/docs/api/overview/

Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/

Python client for pandas:pypi.org/project/genebe/

Java CLI for VCF files:github.com/pstawinski/genebe-cli

All tools documented at:docs.genebe.net

API Request Examples for Variant: 9-137778048-TCG-CTA (hg38)

Bash / cURL Example

bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=9&pos=137778048&ref=TCG&alt=CTA&genome=hg38&allGenes=true"

API Response

json
{
  "message": null,
  "variants": [
    {
      "acmg_by_gene": [
        {
          "benign_score": 0,
          "criteria": [],
          "effects": [
            "missense_variant"
          ],
          "gene_symbol": "EHMT1",
          "hgnc_id": 24650,
          "hgvs_c": "c.2185_2187delTCGinsCTA",
          "hgvs_p": "p.Ser729Leu",
          "inheritance_mode": "AD",
          "pathogenic_score": 0,
          "score": 0,
          "transcript": "NM_024757.5",
          "verdict": "Uncertain_significance"
        },
        {
          "benign_score": 0,
          "criteria": [],
          "effects": [
            "intron_variant"
          ],
          "gene_symbol": "ENSG00000293104",
          "hgnc_id": null,
          "hgvs_c": "n.1061-662_1061-660delCGAinsTAG",
          "hgvs_p": null,
          "inheritance_mode": "",
          "pathogenic_score": 0,
          "score": 0,
          "transcript": "ENST00000626603.1",
          "verdict": "Uncertain_significance"
        }
      ],
      "acmg_classification": "Uncertain_significance",
      "acmg_criteria": "",
      "acmg_score": 0,
      "allele_count_reference_population": 0,
      "alphamissense_prediction": null,
      "alphamissense_score": null,
      "alt": "CTA",
      "apogee2_prediction": null,
      "apogee2_score": null,
      "bayesdelnoaf_prediction": null,
      "bayesdelnoaf_score": null,
      "chr": "9",
      "clinvar_classification": "",
      "clinvar_disease": "",
      "clinvar_review_status": "",
      "clinvar_submissions_summary": "",
      "computational_prediction_selected": null,
      "computational_score_selected": null,
      "computational_source_selected": null,
      "consequences": [
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1298,
          "aa_ref": "S",
          "aa_start": 729,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5095,
          "cdna_start": 2209,
          "cds_end": null,
          "cds_length": 3897,
          "cds_start": 2185,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 27,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "NM_024757.5",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2185_2187delTCGinsCTA",
          "hgvs_p": "p.Ser729Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": "ENST00000460843.6",
          "protein_coding": true,
          "protein_id": "NP_079033.4",
          "strand": true,
          "transcript": "NM_024757.5",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1298,
          "aa_ref": "S",
          "aa_start": 729,
          "biotype": "protein_coding",
          "canonical": true,
          "cdna_end": null,
          "cdna_length": 5095,
          "cdna_start": 2209,
          "cds_end": null,
          "cds_length": 3897,
          "cds_start": 2185,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 27,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "ENST00000460843.6",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2185_2187delTCGinsCTA",
          "hgvs_p": "p.Ser729Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": "NM_024757.5",
          "protein_coding": true,
          "protein_id": "ENSP00000417980.1",
          "strand": true,
          "transcript": "ENST00000460843.6",
          "transcript_support_level": 5
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 808,
          "aa_ref": "S",
          "aa_start": 729,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 2707,
          "cdna_start": 2222,
          "cds_end": null,
          "cds_length": 2427,
          "cds_start": 2185,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 16,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "ENST00000462484.5",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2185_2187delTCGinsCTA",
          "hgvs_p": "p.Ser729Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "ENSP00000417328.1",
          "strand": true,
          "transcript": "ENST00000462484.5",
          "transcript_support_level": 1
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1322,
          "aa_ref": "S",
          "aa_start": 753,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 4789,
          "cdna_start": 2294,
          "cds_end": null,
          "cds_length": 3969,
          "cds_start": 2257,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 28,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "ENST00000896765.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2257_2259delTCGinsCTA",
          "hgvs_p": "p.Ser753Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "ENSP00000566824.1",
          "strand": true,
          "transcript": "ENST00000896765.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1291,
          "aa_ref": "S",
          "aa_start": 722,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5074,
          "cdna_start": 2188,
          "cds_end": null,
          "cds_length": 3876,
          "cds_start": 2164,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 27,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "NM_001354263.2",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2164_2166delTCGinsCTA",
          "hgvs_p": "p.Ser722Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "NP_001341192.1",
          "strand": true,
          "transcript": "NM_001354263.2",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1290,
          "aa_ref": "S",
          "aa_start": 721,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5077,
          "cdna_start": 2194,
          "cds_end": null,
          "cds_length": 3873,
          "cds_start": 2161,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 27,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "ENST00000896763.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2161_2163delTCGinsCTA",
          "hgvs_p": "p.Ser721Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "ENSP00000566822.1",
          "strand": true,
          "transcript": "ENST00000896763.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1276,
          "aa_ref": "S",
          "aa_start": 696,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5029,
          "cdna_start": 2110,
          "cds_end": null,
          "cds_length": 3831,
          "cds_start": 2086,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 26,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "ENST00000918862.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2086_2088delTCGinsCTA",
          "hgvs_p": "p.Ser696Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "ENSP00000588921.1",
          "strand": true,
          "transcript": "ENST00000918862.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1267,
          "aa_ref": "S",
          "aa_start": 698,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5049,
          "cdna_start": 2190,
          "cds_end": null,
          "cds_length": 3804,
          "cds_start": 2092,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 27,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "ENST00000637161.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2092_2094delTCGinsCTA",
          "hgvs_p": "p.Ser698Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "ENSP00000490328.1",
          "strand": true,
          "transcript": "ENST00000637161.1",
          "transcript_support_level": 5
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1265,
          "aa_ref": "S",
          "aa_start": 696,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5021,
          "cdna_start": 2138,
          "cds_end": null,
          "cds_length": 3798,
          "cds_start": 2086,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 26,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "ENST00000896761.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2086_2088delTCGinsCTA",
          "hgvs_p": "p.Ser696Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "ENSP00000566820.1",
          "strand": true,
          "transcript": "ENST00000896761.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1264,
          "aa_ref": "S",
          "aa_start": 695,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5003,
          "cdna_start": 2120,
          "cds_end": null,
          "cds_length": 3795,
          "cds_start": 2083,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 26,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "ENST00000896762.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2083_2085delTCGinsCTA",
          "hgvs_p": "p.Ser695Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "ENSP00000566821.1",
          "strand": true,
          "transcript": "ENST00000896762.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1257,
          "aa_ref": "S",
          "aa_start": 729,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 4566,
          "cdna_start": 2198,
          "cds_end": null,
          "cds_length": 3774,
          "cds_start": 2185,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 26,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "ENST00000896766.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2185_2187delTCGinsCTA",
          "hgvs_p": "p.Ser729Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "ENSP00000566825.1",
          "strand": true,
          "transcript": "ENST00000896766.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1251,
          "aa_ref": "S",
          "aa_start": 696,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 4934,
          "cdna_start": 2090,
          "cds_end": null,
          "cds_length": 3756,
          "cds_start": 2086,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 26,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "ENST00000918863.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2086_2088delTCGinsCTA",
          "hgvs_p": "p.Ser696Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "ENSP00000588922.1",
          "strand": true,
          "transcript": "ENST00000918863.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1224,
          "aa_ref": "S",
          "aa_start": 696,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 4891,
          "cdna_start": 2128,
          "cds_end": null,
          "cds_length": 3675,
          "cds_start": 2086,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 25,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "ENST00000918861.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2086_2088delTCGinsCTA",
          "hgvs_p": "p.Ser696Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "ENSP00000588920.1",
          "strand": true,
          "transcript": "ENST00000918861.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 980,
          "aa_ref": "S",
          "aa_start": 691,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 3114,
          "cdna_start": 2240,
          "cds_end": null,
          "cds_length": 2945,
          "cds_start": 2071,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 21,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "ENST00000636027.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2071_2073delTCGinsCTA",
          "hgvs_p": "p.Ser691Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "ENSP00000489961.1",
          "strand": true,
          "transcript": "ENST00000636027.1",
          "transcript_support_level": 5
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 825,
          "aa_ref": "S",
          "aa_start": 698,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 4585,
          "cdna_start": 2145,
          "cds_end": null,
          "cds_length": 2478,
          "cds_start": 2092,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 16,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "NM_001354259.2",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2092_2094delTCGinsCTA",
          "hgvs_p": "p.Ser698Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "NP_001341188.1",
          "strand": true,
          "transcript": "NM_001354259.2",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 808,
          "aa_ref": "S",
          "aa_start": 729,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 2694,
          "cdna_start": 2209,
          "cds_end": null,
          "cds_length": 2427,
          "cds_start": 2185,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 16,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "NM_001145527.2",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2185_2187delTCGinsCTA",
          "hgvs_p": "p.Ser729Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "NP_001138999.1",
          "strand": true,
          "transcript": "NM_001145527.2",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1301,
          "aa_ref": "S",
          "aa_start": 732,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5181,
          "cdna_start": 2295,
          "cds_end": null,
          "cds_length": 3906,
          "cds_start": 2194,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 27,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_011519021.4",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2194_2196delTCGinsCTA",
          "hgvs_p": "p.Ser732Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_011517323.1",
          "strand": true,
          "transcript": "XM_011519021.4",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1300,
          "aa_ref": "S",
          "aa_start": 731,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5565,
          "cdna_start": 2679,
          "cds_end": null,
          "cds_length": 3903,
          "cds_start": 2191,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 27,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_011519022.4",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2191_2193delTCGinsCTA",
          "hgvs_p": "p.Ser731Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_011517324.1",
          "strand": true,
          "transcript": "XM_011519022.4",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1295,
          "aa_ref": "S",
          "aa_start": 726,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5198,
          "cdna_start": 2312,
          "cds_end": null,
          "cds_length": 3888,
          "cds_start": 2176,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 28,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_047423872.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2176_2178delTCGinsCTA",
          "hgvs_p": "p.Ser726Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_047279828.1",
          "strand": true,
          "transcript": "XM_047423872.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1294,
          "aa_ref": "S",
          "aa_start": 725,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5160,
          "cdna_start": 2274,
          "cds_end": null,
          "cds_length": 3885,
          "cds_start": 2173,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 27,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_011519023.4",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2173_2175delTCGinsCTA",
          "hgvs_p": "p.Ser725Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_011517325.1",
          "strand": true,
          "transcript": "XM_011519023.4",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1293,
          "aa_ref": "S",
          "aa_start": 724,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5544,
          "cdna_start": 2658,
          "cds_end": null,
          "cds_length": 3882,
          "cds_start": 2170,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 27,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_017015134.2",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2170_2172delTCGinsCTA",
          "hgvs_p": "p.Ser724Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_016870623.1",
          "strand": true,
          "transcript": "XM_017015134.2",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1288,
          "aa_ref": "S",
          "aa_start": 719,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 13318,
          "cdna_start": 10432,
          "cds_end": null,
          "cds_length": 3867,
          "cds_start": 2155,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 28,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_047423873.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2155_2157delTCGinsCTA",
          "hgvs_p": "p.Ser719Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_047279829.1",
          "strand": true,
          "transcript": "XM_047423873.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1275,
          "aa_ref": "S",
          "aa_start": 706,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5103,
          "cdna_start": 2217,
          "cds_end": null,
          "cds_length": 3828,
          "cds_start": 2116,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 26,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_047423874.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2116_2118delTCGinsCTA",
          "hgvs_p": "p.Ser706Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_047279830.1",
          "strand": true,
          "transcript": "XM_047423874.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1269,
          "aa_ref": "S",
          "aa_start": 700,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5120,
          "cdna_start": 2234,
          "cds_end": null,
          "cds_length": 3810,
          "cds_start": 2098,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 27,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_047423875.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2098_2100delTCGinsCTA",
          "hgvs_p": "p.Ser700Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_047279831.1",
          "strand": true,
          "transcript": "XM_047423875.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1268,
          "aa_ref": "S",
          "aa_start": 699,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5082,
          "cdna_start": 2196,
          "cds_end": null,
          "cds_length": 3807,
          "cds_start": 2095,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 26,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_047423876.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2095_2097delTCGinsCTA",
          "hgvs_p": "p.Ser699Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_047279832.1",
          "strand": true,
          "transcript": "XM_047423876.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1267,
          "aa_ref": "S",
          "aa_start": 698,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5031,
          "cdna_start": 2145,
          "cds_end": null,
          "cds_length": 3804,
          "cds_start": 2092,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 26,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_005266110.2",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2092_2094delTCGinsCTA",
          "hgvs_p": "p.Ser698Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_005266167.1",
          "strand": true,
          "transcript": "XM_005266110.2",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1267,
          "aa_ref": "S",
          "aa_start": 698,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5174,
          "cdna_start": 2288,
          "cds_end": null,
          "cds_length": 3804,
          "cds_start": 2092,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 27,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_047423877.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2092_2094delTCGinsCTA",
          "hgvs_p": "p.Ser698Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_047279833.1",
          "strand": true,
          "transcript": "XM_047423877.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1267,
          "aa_ref": "S",
          "aa_start": 698,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5134,
          "cdna_start": 2248,
          "cds_end": null,
          "cds_length": 3804,
          "cds_start": 2092,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 27,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_047423878.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2092_2094delTCGinsCTA",
          "hgvs_p": "p.Ser698Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_047279834.1",
          "strand": true,
          "transcript": "XM_047423878.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1260,
          "aa_ref": "S",
          "aa_start": 691,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5010,
          "cdna_start": 2124,
          "cds_end": null,
          "cds_length": 3783,
          "cds_start": 2071,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 26,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_017015138.2",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2071_2073delTCGinsCTA",
          "hgvs_p": "p.Ser691Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_016870627.1",
          "strand": true,
          "transcript": "XM_017015138.2",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1260,
          "aa_ref": "S",
          "aa_start": 691,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5077,
          "cdna_start": 2191,
          "cds_end": null,
          "cds_length": 3783,
          "cds_start": 2071,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 27,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_047423879.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2071_2073delTCGinsCTA",
          "hgvs_p": "p.Ser691Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_047279835.1",
          "strand": true,
          "transcript": "XM_047423879.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1253,
          "aa_ref": "S",
          "aa_start": 684,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 5037,
          "cdna_start": 2151,
          "cds_end": null,
          "cds_length": 3762,
          "cds_start": 2050,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 26,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_047423880.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2050_2052delTCGinsCTA",
          "hgvs_p": "p.Ser684Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_047279836.1",
          "strand": true,
          "transcript": "XM_047423880.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1241,
          "aa_ref": "S",
          "aa_start": 672,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 4953,
          "cdna_start": 2067,
          "cds_end": null,
          "cds_length": 3726,
          "cds_start": 2014,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 25,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_047423881.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2014_2016delTCGinsCTA",
          "hgvs_p": "p.Ser672Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_047279837.1",
          "strand": true,
          "transcript": "XM_047423881.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1234,
          "aa_ref": "S",
          "aa_start": 665,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 4932,
          "cdna_start": 2046,
          "cds_end": null,
          "cds_length": 3705,
          "cds_start": 1993,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 25,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_047423882.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.1993_1995delTCGinsCTA",
          "hgvs_p": "p.Ser665Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_047279838.1",
          "strand": true,
          "transcript": "XM_047423882.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1219,
          "aa_ref": "S",
          "aa_start": 650,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 4887,
          "cdna_start": 2001,
          "cds_end": null,
          "cds_length": 3660,
          "cds_start": 1948,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 25,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_047423883.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.1948_1950delTCGinsCTA",
          "hgvs_p": "p.Ser650Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_047279839.1",
          "strand": true,
          "transcript": "XM_047423883.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1212,
          "aa_ref": "S",
          "aa_start": 643,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 4866,
          "cdna_start": 1980,
          "cds_end": null,
          "cds_length": 3639,
          "cds_start": 1927,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 25,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_047423884.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.1927_1929delTCGinsCTA",
          "hgvs_p": "p.Ser643Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_047279840.1",
          "strand": true,
          "transcript": "XM_047423884.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1186,
          "aa_ref": "S",
          "aa_start": 617,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 4788,
          "cdna_start": 1902,
          "cds_end": null,
          "cds_length": 3561,
          "cds_start": 1849,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 24,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_047423885.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.1849_1851delTCGinsCTA",
          "hgvs_p": "p.Ser617Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_047279841.1",
          "strand": true,
          "transcript": "XM_047423885.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 1006,
          "aa_ref": "S",
          "aa_start": 437,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 14472,
          "cdna_start": 11586,
          "cds_end": null,
          "cds_length": 3021,
          "cds_start": 1309,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 24,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_024447677.2",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.1309_1311delTCGinsCTA",
          "hgvs_p": "p.Ser437Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_024303445.1",
          "strand": true,
          "transcript": "XM_024447677.2",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 927,
          "aa_ref": "S",
          "aa_start": 729,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 3075,
          "cdna_start": 2209,
          "cds_end": null,
          "cds_length": 2784,
          "cds_start": 2185,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 19,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_024447678.2",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2185_2187delTCGinsCTA",
          "hgvs_p": "p.Ser729Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_024303446.2",
          "strand": true,
          "transcript": "XM_024447678.2",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 896,
          "aa_ref": "S",
          "aa_start": 698,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 3011,
          "cdna_start": 2145,
          "cds_end": null,
          "cds_length": 2691,
          "cds_start": 2092,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 18,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_047423886.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2092_2094delTCGinsCTA",
          "hgvs_p": "p.Ser698Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_047279842.1",
          "strand": true,
          "transcript": "XM_047423886.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 889,
          "aa_ref": "S",
          "aa_start": 691,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 2990,
          "cdna_start": 2124,
          "cds_end": null,
          "cds_length": 2670,
          "cds_start": 2071,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 18,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_047423887.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2071_2073delTCGinsCTA",
          "hgvs_p": "p.Ser691Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_047279843.1",
          "strand": true,
          "transcript": "XM_047423887.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 870,
          "aa_ref": "S",
          "aa_start": 672,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 2933,
          "cdna_start": 2067,
          "cds_end": null,
          "cds_length": 2613,
          "cds_start": 2014,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 17,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_047423888.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.2014_2016delTCGinsCTA",
          "hgvs_p": "p.Ser672Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_047279844.1",
          "strand": true,
          "transcript": "XM_047423888.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 863,
          "aa_ref": "S",
          "aa_start": 665,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 2912,
          "cdna_start": 2046,
          "cds_end": null,
          "cds_length": 2592,
          "cds_start": 1993,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 17,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_047423889.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.1993_1995delTCGinsCTA",
          "hgvs_p": "p.Ser665Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_047279845.1",
          "strand": true,
          "transcript": "XM_047423889.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": "L",
          "aa_end": null,
          "aa_length": 775,
          "aa_ref": "S",
          "aa_start": 206,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 3722,
          "cdna_start": 836,
          "cds_end": null,
          "cds_length": 2328,
          "cds_start": 616,
          "consequences": [
            "missense_variant"
          ],
          "exon_count": 19,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "XM_011519029.4",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.616_618delTCGinsCTA",
          "hgvs_p": "p.Ser206Leu",
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "XP_011517331.1",
          "strand": true,
          "transcript": "XM_011519029.4",
          "transcript_support_level": null
        },
        {
          "aa_alt": null,
          "aa_end": null,
          "aa_length": 1053,
          "aa_ref": null,
          "aa_start": null,
          "biotype": "protein_coding",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 4356,
          "cdna_start": null,
          "cds_end": null,
          "cds_length": 3162,
          "cds_start": null,
          "consequences": [
            "intron_variant"
          ],
          "exon_count": 22,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "ENST00000896764.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "c.1648-12800_1648-12798delTCGinsCTA",
          "hgvs_p": null,
          "intron_rank": 10,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": true,
          "protein_id": "ENSP00000566823.1",
          "strand": true,
          "transcript": "ENST00000896764.1",
          "transcript_support_level": null
        },
        {
          "aa_alt": null,
          "aa_end": null,
          "aa_length": null,
          "aa_ref": null,
          "aa_start": null,
          "biotype": "nonsense_mediated_decay",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 2679,
          "cdna_start": null,
          "cds_end": null,
          "cds_length": null,
          "cds_start": null,
          "consequences": [
            "non_coding_transcript_exon_variant"
          ],
          "exon_count": 16,
          "exon_rank": 12,
          "exon_rank_end": null,
          "feature": "ENST00000371394.6",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "n.*1920_*1922delTCGinsCTA",
          "hgvs_p": null,
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": false,
          "protein_id": "ENSP00000485945.1",
          "strand": true,
          "transcript": "ENST00000371394.6",
          "transcript_support_level": 2
        },
        {
          "aa_alt": null,
          "aa_end": null,
          "aa_length": null,
          "aa_ref": null,
          "aa_start": null,
          "biotype": "nonsense_mediated_decay",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 7842,
          "cdna_start": null,
          "cds_end": null,
          "cds_length": null,
          "cds_start": null,
          "consequences": [
            "non_coding_transcript_exon_variant"
          ],
          "exon_count": 22,
          "exon_rank": 8,
          "exon_rank_end": null,
          "feature": "ENST00000462942.3",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "n.1042_1044delTCGinsCTA",
          "hgvs_p": null,
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": false,
          "protein_id": "ENSP00000436107.1",
          "strand": true,
          "transcript": "ENST00000462942.3",
          "transcript_support_level": 2
        },
        {
          "aa_alt": null,
          "aa_end": null,
          "aa_length": null,
          "aa_ref": null,
          "aa_start": null,
          "biotype": "nonsense_mediated_decay",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 4208,
          "cdna_start": null,
          "cds_end": null,
          "cds_length": null,
          "cds_start": null,
          "consequences": [
            "non_coding_transcript_exon_variant"
          ],
          "exon_count": 24,
          "exon_rank": 12,
          "exon_rank_end": null,
          "feature": "ENST00000637261.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "n.*1391_*1393delTCGinsCTA",
          "hgvs_p": null,
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": false,
          "protein_id": "ENSP00000490815.1",
          "strand": true,
          "transcript": "ENST00000637261.1",
          "transcript_support_level": 5
        },
        {
          "aa_alt": null,
          "aa_end": null,
          "aa_length": null,
          "aa_ref": null,
          "aa_start": null,
          "biotype": "nonsense_mediated_decay",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 1930,
          "cdna_start": null,
          "cds_end": null,
          "cds_length": null,
          "cds_start": null,
          "consequences": [
            "non_coding_transcript_exon_variant"
          ],
          "exon_count": 15,
          "exon_rank": 1,
          "exon_rank_end": null,
          "feature": "ENST00000637891.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "n.79_81delTCGinsCTA",
          "hgvs_p": null,
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": false,
          "protein_id": "ENSP00000490907.1",
          "strand": true,
          "transcript": "ENST00000637891.1",
          "transcript_support_level": 5
        },
        {
          "aa_alt": null,
          "aa_end": null,
          "aa_length": null,
          "aa_ref": null,
          "aa_start": null,
          "biotype": "nonsense_mediated_decay",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 2679,
          "cdna_start": null,
          "cds_end": null,
          "cds_length": null,
          "cds_start": null,
          "consequences": [
            "3_prime_UTR_variant"
          ],
          "exon_count": 16,
          "exon_rank": 12,
          "exon_rank_end": null,
          "feature": "ENST00000371394.6",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "n.*1920_*1922delTCGinsCTA",
          "hgvs_p": null,
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": false,
          "protein_id": "ENSP00000485945.1",
          "strand": true,
          "transcript": "ENST00000371394.6",
          "transcript_support_level": 2
        },
        {
          "aa_alt": null,
          "aa_end": null,
          "aa_length": null,
          "aa_ref": null,
          "aa_start": null,
          "biotype": "nonsense_mediated_decay",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 4208,
          "cdna_start": null,
          "cds_end": null,
          "cds_length": null,
          "cds_start": null,
          "consequences": [
            "3_prime_UTR_variant"
          ],
          "exon_count": 24,
          "exon_rank": 12,
          "exon_rank_end": null,
          "feature": "ENST00000637261.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "n.*1391_*1393delTCGinsCTA",
          "hgvs_p": null,
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": false,
          "protein_id": "ENSP00000490815.1",
          "strand": true,
          "transcript": "ENST00000637261.1",
          "transcript_support_level": 5
        },
        {
          "aa_alt": null,
          "aa_end": null,
          "aa_length": null,
          "aa_ref": null,
          "aa_start": null,
          "biotype": "pseudogene",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 1910,
          "cdna_start": null,
          "cds_end": null,
          "cds_length": null,
          "cds_start": null,
          "consequences": [
            "intron_variant"
          ],
          "exon_count": 2,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "ENST00000626603.1",
          "gene_hgnc_id": null,
          "gene_symbol": "ENSG00000293104",
          "hgvs_c": "n.1061-662_1061-660delCGAinsTAG",
          "hgvs_p": null,
          "intron_rank": 1,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": false,
          "protein_id": null,
          "strand": false,
          "transcript": "ENST00000626603.1",
          "transcript_support_level": 2
        },
        {
          "aa_alt": null,
          "aa_end": null,
          "aa_length": null,
          "aa_ref": null,
          "aa_start": null,
          "biotype": "nonsense_mediated_decay",
          "canonical": false,
          "cdna_end": null,
          "cdna_length": 1710,
          "cdna_start": null,
          "cds_end": null,
          "cds_length": null,
          "cds_start": null,
          "consequences": [
            "downstream_gene_variant"
          ],
          "exon_count": 10,
          "exon_rank": null,
          "exon_rank_end": null,
          "feature": "ENST00000638071.1",
          "gene_hgnc_id": 24650,
          "gene_symbol": "EHMT1",
          "hgvs_c": "n.*1475_*1477delTCGinsCTA",
          "hgvs_p": null,
          "intron_rank": null,
          "intron_rank_end": null,
          "mane_plus": null,
          "mane_select": null,
          "protein_coding": false,
          "protein_id": "ENSP00000490417.1",
          "strand": true,
          "transcript": "ENST00000638071.1",
          "transcript_support_level": 5
        }
      ],
      "custom_annotations": null,
      "dbscsnv_ada_prediction": null,
      "dbscsnv_ada_score": null,
      "dbsnp": null,
      "effect": "missense_variant",
      "frequency_reference_population": null,
      "gene_hgnc_id": 24650,
      "gene_symbol": "EHMT1",
      "gnomad_exomes_ac": null,
      "gnomad_exomes_af": null,
      "gnomad_exomes_homalt": null,
      "gnomad_genomes_ac": null,
      "gnomad_genomes_af": null,
      "gnomad_genomes_homalt": null,
      "gnomad_mito_heteroplasmic": null,
      "gnomad_mito_homoplasmic": null,
      "hom_count_reference_population": 0,
      "mitotip_prediction": null,
      "mitotip_score": null,
      "pathogenicity_classification_combined": null,
      "phenotype_combined": null,
      "phylop100way_prediction": "Uncertain_significance",
      "phylop100way_score": 5.428,
      "pos": 137778048,
      "ref": "TCG",
      "revel_prediction": null,
      "revel_score": null,
      "splice_prediction_selected": null,
      "splice_score_selected": null,
      "splice_source_selected": null,
      "spliceai_max_prediction": null,
      "spliceai_max_score": null,
      "transcript": "NM_024757.5"
    }
  ]
}
For research and educational, non-commercial use only. Not for clinical or diagnostic use. GeneBe does not provide medical advice. Data use for AI modeling is prohibited: if used, the cost is $0.001 per byte of downloaded uncompressed data.