← Back to variant description

GeneBe API Showcase

This page demonstrates how to use the GeneBe API to query variant information. The API provides programmatic access to genomic annotations and variant data.

API presented here should be used for checking single variants. If you want to check many variants at once, please use other API endpoints that you will find in the documentation.

Documentation & Advanced Usage

Complete API documentation:docs.genebe.net/docs/api/overview/

Interactive endpoint tester:api.genebe.net/cloud/gb-api-doc/swagger-ui/

Python client for pandas:pypi.org/project/genebe/

Java CLI for VCF files:github.com/pstawinski/genebe-cli

All tools documented at:docs.genebe.net

API Request Examples for Variant: X-18901437-G-C (hg38)

Bash / cURL Example

bash
curl "https://api.genebe.net/cloud/api-public/v1/variant?chr=X&pos=18901437&ref=G&alt=C&genome=hg38&allGenes=true"

API Response

json
{
  "variants": [
    {
      "chr": "X",
      "pos": 18901437,
      "ref": "G",
      "alt": "C",
      "effect": "intron_variant",
      "transcript": "NM_001440805.1",
      "consequences": [
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 33,
          "intron_rank": 27,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.3027+48C>G",
          "hgvs_p": null,
          "transcript": "NM_000292.3",
          "protein_id": "NP_000283.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1235,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3708,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 5077,
          "mane_select": "ENST00000379942.5",
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "NM_000292.3"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": true,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 33,
          "intron_rank": 27,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.3027+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000379942.5",
          "protein_id": "ENSP00000369274.4",
          "transcript_support_level": 1,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1235,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3708,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 5077,
          "mane_select": "NM_000292.3",
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000379942.5"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 33,
          "intron_rank": 27,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.3027+48C>G",
          "hgvs_p": null,
          "transcript": "NM_001440805.1",
          "protein_id": "NP_001427734.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1243,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3732,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 5101,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "NM_001440805.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 33,
          "intron_rank": 27,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.3027+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000897868.1",
          "protein_id": "ENSP00000567927.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1243,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3732,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 5529,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000897868.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 33,
          "intron_rank": 27,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.3012+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000954730.1",
          "protein_id": "ENSP00000624789.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1230,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3693,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4596,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000954730.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 33,
          "intron_rank": 27,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.3027+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000897873.1",
          "protein_id": "ENSP00000567932.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1226,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3681,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4524,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000897873.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 32,
          "intron_rank": 27,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.3027+48C>G",
          "hgvs_p": null,
          "transcript": "NM_001440800.1",
          "protein_id": "NP_001427729.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1217,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3654,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 5023,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "NM_001440800.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 32,
          "intron_rank": 27,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.3027+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000897869.1",
          "protein_id": "ENSP00000567928.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1217,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3654,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 5144,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000897869.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 31,
          "intron_rank": 27,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.3027+48C>G",
          "hgvs_p": null,
          "transcript": "NM_001440801.1",
          "protein_id": "NP_001427730.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1207,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3624,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4993,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "NM_001440801.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 31,
          "intron_rank": 27,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.3027+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000897867.1",
          "protein_id": "ENSP00000567926.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1207,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3624,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 5553,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000897867.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 31,
          "intron_rank": 27,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.3021+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000954732.1",
          "protein_id": "ENSP00000624791.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1205,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3618,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4311,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000954732.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 32,
          "intron_rank": 26,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.2928+48C>G",
          "hgvs_p": null,
          "transcript": "NM_001440802.1",
          "protein_id": "NP_001427731.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1202,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3609,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4978,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "NM_001440802.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 32,
          "intron_rank": 26,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.2928+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000897870.1",
          "protein_id": "ENSP00000567929.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1202,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3609,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 5098,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000897870.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 31,
          "intron_rank": 27,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.3012+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000934920.1",
          "protein_id": "ENSP00000604979.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1202,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3609,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4694,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000934920.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 30,
          "intron_rank": 26,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.2979+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000934921.1",
          "protein_id": "ENSP00000604980.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1191,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3576,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4534,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000934921.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 31,
          "intron_rank": 26,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.2946+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000954728.1",
          "protein_id": "ENSP00000624787.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1190,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3573,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4563,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000954728.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 30,
          "intron_rank": 27,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.3027+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000934923.1",
          "protein_id": "ENSP00000604982.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1189,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3570,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4222,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000934923.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 31,
          "intron_rank": 26,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.2928+48C>G",
          "hgvs_p": null,
          "transcript": "NM_001440803.1",
          "protein_id": "NP_001427732.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1184,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3555,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4924,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "NM_001440803.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 31,
          "intron_rank": 26,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.2928+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000954729.1",
          "protein_id": "ENSP00000624788.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1184,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3555,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4500,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000954729.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 30,
          "intron_rank": 26,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.2928+48C>G",
          "hgvs_p": null,
          "transcript": "NM_001440804.1",
          "protein_id": "NP_001427733.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1174,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3525,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4894,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "NM_001440804.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 30,
          "intron_rank": 26,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.2928+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000897871.1",
          "protein_id": "ENSP00000567930.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1174,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3525,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4918,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000897871.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 30,
          "intron_rank": 26,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.2919+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000934922.1",
          "protein_id": "ENSP00000604981.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1171,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3516,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4194,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000934922.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 30,
          "intron_rank": 26,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.2853+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000954731.1",
          "protein_id": "ENSP00000624790.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1149,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3450,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4145,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000954731.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 29,
          "intron_rank": 23,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.2646+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000897872.1",
          "protein_id": "ENSP00000567931.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1108,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3327,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4278,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000897872.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 24,
          "intron_rank": 20,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.2346+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000954727.1",
          "protein_id": "ENSP00000624786.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 980,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 2943,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4096,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "ENST00000954727.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 32,
          "intron_rank": 26,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.2928+48C>G",
          "hgvs_p": null,
          "transcript": "XM_011545537.4",
          "protein_id": "XP_011543839.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1210,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3633,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 5002,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "XM_011545537.4"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 31,
          "intron_rank": 25,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.2481+48C>G",
          "hgvs_p": null,
          "transcript": "XM_047442166.1",
          "protein_id": "XP_047298122.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 1061,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 3186,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4558,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "XM_047442166.1"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 26,
          "intron_rank": 20,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.2121+48C>G",
          "hgvs_p": null,
          "transcript": "XM_017029580.3",
          "protein_id": "XP_016885069.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 941,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 2826,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4119,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "XM_017029580.3"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": true,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 24,
          "intron_rank": 18,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "c.2010+48C>G",
          "hgvs_p": null,
          "transcript": "XM_011545538.4",
          "protein_id": "XP_011543840.1",
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": 904,
          "cds_start": null,
          "cds_end": null,
          "cds_length": 2715,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4019,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "protein_coding",
          "feature": "XM_011545538.4"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": false,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 7,
          "intron_rank": 5,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "n.511+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000469645.5",
          "protein_id": null,
          "transcript_support_level": 5,
          "aa_start": null,
          "aa_end": null,
          "aa_length": null,
          "cds_start": null,
          "cds_end": null,
          "cds_length": null,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 728,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "pseudogene",
          "feature": "ENST00000469645.5"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": false,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 6,
          "intron_rank": 1,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "n.119+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000473739.5",
          "protein_id": null,
          "transcript_support_level": 3,
          "aa_start": null,
          "aa_end": null,
          "aa_length": null,
          "cds_start": null,
          "cds_end": null,
          "cds_length": null,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 751,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "pseudogene",
          "feature": "ENST00000473739.5"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": false,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 4,
          "intron_rank": 3,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "n.296+48C>G",
          "hgvs_p": null,
          "transcript": "ENST00000486231.2",
          "protein_id": null,
          "transcript_support_level": 5,
          "aa_start": null,
          "aa_end": null,
          "aa_length": null,
          "cds_start": null,
          "cds_end": null,
          "cds_length": null,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 317,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "pseudogene",
          "feature": "ENST00000486231.2"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": false,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 30,
          "intron_rank": 27,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "n.3209+48C>G",
          "hgvs_p": null,
          "transcript": "XR_001755697.3",
          "protein_id": null,
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": null,
          "cds_start": null,
          "cds_end": null,
          "cds_length": null,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 3464,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "pseudogene",
          "feature": "XR_001755697.3"
        },
        {
          "aa_ref": null,
          "aa_alt": null,
          "canonical": false,
          "protein_coding": false,
          "strand": false,
          "consequences": [
            "intron_variant"
          ],
          "exon_rank": null,
          "exon_rank_end": null,
          "exon_count": 30,
          "intron_rank": 27,
          "intron_rank_end": null,
          "gene_symbol": "PHKA2",
          "gene_hgnc_id": 8926,
          "hgvs_c": "n.3209+48C>G",
          "hgvs_p": null,
          "transcript": "XR_950461.4",
          "protein_id": null,
          "transcript_support_level": null,
          "aa_start": null,
          "aa_end": null,
          "aa_length": null,
          "cds_start": null,
          "cds_end": null,
          "cds_length": null,
          "cdna_start": null,
          "cdna_end": null,
          "cdna_length": 4716,
          "mane_select": null,
          "mane_plus": null,
          "biotype": "pseudogene",
          "feature": "XR_950461.4"
        }
      ],
      "gene_symbol": "PHKA2",
      "gene_hgnc_id": 8926,
      "dbsnp": "rs201339926",
      "frequency_reference_population": 0.000003583964,
      "hom_count_reference_population": 0,
      "allele_count_reference_population": 3,
      "gnomad_exomes_af": 0.00000275546,
      "gnomad_genomes_af": 0.00000899038,
      "gnomad_exomes_ac": 2,
      "gnomad_genomes_ac": 1,
      "gnomad_exomes_homalt": 0,
      "gnomad_genomes_homalt": 0,
      "gnomad_mito_homoplasmic": null,
      "gnomad_mito_heteroplasmic": null,
      "computational_score_selected": -0.8199999928474426,
      "computational_prediction_selected": "Benign",
      "computational_source_selected": "BayesDel_noAF",
      "splice_score_selected": 0.009999999776482582,
      "splice_prediction_selected": "Benign",
      "splice_source_selected": "max_spliceai",
      "revel_score": null,
      "revel_prediction": null,
      "alphamissense_score": null,
      "alphamissense_prediction": null,
      "bayesdelnoaf_score": -0.82,
      "bayesdelnoaf_prediction": "Benign",
      "phylop100way_score": 1.947,
      "phylop100way_prediction": "Benign",
      "spliceai_max_score": 0.01,
      "spliceai_max_prediction": "Benign",
      "dbscsnv_ada_score": null,
      "dbscsnv_ada_prediction": null,
      "apogee2_score": null,
      "apogee2_prediction": null,
      "mitotip_score": null,
      "mitotip_prediction": null,
      "acmg_score": -2,
      "acmg_classification": "Likely_benign",
      "acmg_criteria": "PM2,BP4_Strong",
      "acmg_by_gene": [
        {
          "score": -2,
          "benign_score": 4,
          "pathogenic_score": 2,
          "criteria": [
            "PM2",
            "BP4_Strong"
          ],
          "verdict": "Likely_benign",
          "transcript": "NM_001440805.1",
          "gene_symbol": "PHKA2",
          "hgnc_id": 8926,
          "effects": [
            "intron_variant"
          ],
          "inheritance_mode": "XL,AR",
          "hgvs_c": "c.3027+48C>G",
          "hgvs_p": null
        }
      ],
      "clinvar_disease": "",
      "clinvar_classification": "",
      "clinvar_review_status": "",
      "clinvar_submissions_summary": "",
      "phenotype_combined": null,
      "pathogenicity_classification_combined": null,
      "custom_annotations": null
    }
  ],
  "message": null
}
For research and educational, non-commercial use only. Not for clinical or diagnostic use. GeneBe does not provide medical advice. Data use for AI modeling is prohibited: if used, the cost is $0.001 per byte of downloaded uncompressed data.