ADAM7-AS2

ADAM7 antisense RNA 2, the group of Antisense RNAs

Basic information

Region (hg38): 8:24490312-24524887

Links

ENSG00000253643 ∙ NCBI:101929315 ∙ ∙ HGNC:56153 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the ADAM7-AS2 gene.

• Inborn genetic diseases (20 variants)
• not provided (1 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the ADAM7-AS2 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			20	1		21
Total	0	0	20	1	0

Variants in ADAM7-AS2

This is a list of pathogenic ClinVar variants found in the ADAM7-AS2 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
8-24490857-G-A		not specified	Uncertain significance (Jul 14, 2021)
8-24490869-A-G		not specified	Uncertain significance (Aug 10, 2021)
8-24490886-C-G		not specified	Uncertain significance (Apr 19, 2024)
8-24491910-A-G		not specified	Uncertain significance (Sep 01, 2021)
8-24491913-C-T		not specified	Uncertain significance (May 24, 2024)
8-24491934-C-A		not specified	Uncertain significance (May 25, 2022)
8-24492003-G-A		not specified	Uncertain significance (Nov 06, 2023)
8-24492021-G-A		not specified	Uncertain significance (Nov 07, 2022)
8-24492046-C-A		not specified	Uncertain significance (Mar 25, 2022)
8-24492574-C-G		not specified	Uncertain significance (Jul 20, 2021)
8-24493054-G-A		not specified	Uncertain significance (Nov 01, 2022)
8-24493099-G-C		not specified	Uncertain significance (Jun 05, 2024)
8-24493128-C-A		not specified	Uncertain significance (May 20, 2024)
8-24493156-A-G		not specified	Uncertain significance (Apr 17, 2023)
8-24493161-A-C		not specified	Uncertain significance (Jun 02, 2023)
8-24493173-C-A		not specified	Uncertain significance (Nov 09, 2021)
8-24493197-G-C		not specified	Uncertain significance (Jul 27, 2022)
8-24493224-G-C		not specified	Uncertain significance (Sep 06, 2022)
8-24499238-G-C			Likely benign (Mar 01, 2022)
8-24499311-A-C		not specified	Uncertain significance (May 30, 2024)
8-24500235-G-A		not specified	Uncertain significance (Aug 17, 2022)
8-24500813-C-T		not specified	Uncertain significance (Aug 02, 2022)
8-24500828-G-A		not specified	Likely benign (Jan 17, 2024)
8-24500837-G-A		not specified	Uncertain significance (Jul 25, 2023)
8-24500859-G-A		not specified	Uncertain significance (Sep 01, 2021)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP