CASC15

cancer susceptibility 15, the group of Long non-coding RNAs with non-systematic symbols

Basic information

Region (hg38): 6:21664164-22660021

Previous symbols: [ "LINC00340" ]

Links

ENSG00000272168 ∙ NCBI:401237 ∙ OMIM:616610 ∙ HGNC:28245 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the CASC15 gene.

• Inborn genetic diseases (18 variants)
• not provided (4 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the CASC15 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			16	3	3	22
Total	0	0	16	3	3

Variants in CASC15

This is a list of pathogenic ClinVar variants found in the CASC15 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
6-22287456-G-A			Likely benign (Mar 29, 2018)
6-22287467-A-C		not specified	Uncertain significance (Jan 22, 2024)
6-22290233-C-T		not specified	Likely benign (Apr 13, 2022)
6-22290279-T-G		not specified	Uncertain significance (Apr 01, 2024)
6-22292550-G-A			Benign (Jan 25, 2018)
6-22292568-G-A			Benign (Mar 29, 2018)
6-22292572-G-A		not specified	Uncertain significance (Sep 13, 2023)
6-22292587-G-A		not specified	Uncertain significance (May 16, 2024)
6-22292590-T-C		not specified	Uncertain significance (Nov 12, 2021)
6-22292623-C-A		not specified	Uncertain significance (Oct 17, 2023)
6-22292624-G-A		not specified	Uncertain significance (Jan 30, 2024)
6-22292638-C-T		not specified	Likely benign (Oct 20, 2021)
6-22294443-A-G		not specified	Uncertain significance (Mar 25, 2024)
6-22294535-C-T			Benign (Jan 25, 2018)
6-22569583-C-T		not specified	Uncertain significance (Feb 27, 2023)
6-22569588-G-A		not specified	Uncertain significance (Mar 28, 2023)
6-22569640-A-G		not specified	Uncertain significance (Dec 08, 2023)
6-22569663-G-C		not specified	Uncertain significance (Jun 16, 2023)
6-22569739-G-A		not specified	Likely benign (Dec 21, 2022)
6-22569784-A-G		not specified	Uncertain significance (Jan 09, 2024)
6-22569850-A-G		not specified	Uncertain significance (Jun 13, 2022)
6-22569855-C-T		not specified	Uncertain significance (Sep 26, 2023)
6-22569861-G-A		not specified	Uncertain significance (Jul 12, 2023)
6-22569864-T-G		not specified	Uncertain significance (Aug 30, 2022)
6-22569915-G-A		not specified	Uncertain significance (Apr 09, 2024)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP