CCR5AS

CCR5 antisense RNA, the group of Long non-coding RNAs with non-systematic symbols

Basic information

Links

ENSG00000223552

∙ NCBI:102724297 ∙ ∙ HGNC:54398 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the CCR5AS gene.

Inborn genetic diseases (10 variants)
Susceptibility to HIV infection (4 variants)
not provided (2 variants)
CCR5-related condition (2 variants)
Human immunodeficiency virus type 1, increased perinatal transmission of (1 variants)
Acquired immunodeficiency syndrome, delayed progression to (1 variants)
CCR5 POLYMORPHISM, AFRICAN-AMERICAN (1 variants)
not specified (1 variants)
CCR5 PROMOTER POLYMORPHISM (1 variants)
CCR5 POLYMORPHISM, ORIENTAL 2 (1 variants)
CCR5 POLYMORPHISM, ORIENTAL 1 (1 variants)
West Nile virus, susceptibility to (1 variants)
Resistance to hepatitis C virus (1 variants)
Hepatitis C virus, susceptibility to;Susceptibility to HIV infection;West Nile virus, susceptibility to;Type 1 diabetes mellitus 22 (1 variants)
Multiple sclerosis modifier of disease progression (1 variants)
West Nile virus, susceptibility to;Type 1 diabetes mellitus 22 (1 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the CCR5AS gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region ? Intron variants in splice region, excluding donor/acceptor (+/-2bp)						0
non coding ? UTR, intron and other, non coding variants			14 clinvar		5 clinvar	19
Total	0	0	14	0	5

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP