CERNA3

competing endogenous lncRNA 3 for miR-645, the group of Long non-coding RNAs with non-systematic symbols

Basic information

Region (hg38): 8:56074273-56081877

Links

ENSG00000253603 ∙ NCBI:105375847 ∙ ∙ HGNC:53469 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the CERNA3 gene.

• not provided (7 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the CERNA3 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding					7	7
Total	0	0	0	0	7

Variants in CERNA3

This is a list of pathogenic ClinVar variants found in the CERNA3 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
8-56074324-G-C			Benign (Jun 15, 2019)
8-56074352-G-A		not specified	Likely benign (Mar 04, 2025)
8-56074360-C-T		not specified	Likely benign (Mar 04, 2025)
8-56074360-CGCCGCCGACT-C			Uncertain significance (Jan 13, 2023)
8-56074366-C-T			Likely benign (Feb 10, 2023)
8-56074368-A-C			Benign (Sep 18, 2024)
8-56074368-ACT-CCC		Diamond-Blackfan anemia	Uncertain significance (Feb 05, 2025)
8-56074370-T-C			Likely benign (Sep 18, 2024)
8-56074371-G-T		RPS20-related disorder	Likely benign (Feb 15, 2021)
8-56074372-C-A			Likely benign (Feb 24, 2024)
8-56074374-G-A			Likely benign (May 14, 2024)
8-56074376-C-T			Uncertain significance (Apr 20, 2020)
8-56074381-C-T			Uncertain significance (Aug 24, 2021)
8-56074386-C-A		not specified	Uncertain significance (Mar 04, 2025)
8-56074389-T-C		Lynch syndrome • not specified	Benign (Mar 04, 2025)
8-56074405-T-C		not specified	Likely benign (Mar 04, 2025)
8-56074416-T-A		not specified	Likely benign (Mar 04, 2025)
8-56074427-G-A		not specified	Likely benign (Mar 04, 2025)
8-56074473-C-A			Likely benign (Nov 11, 2021)
8-56074500-C-G			Benign (Jun 15, 2019)
8-56074681-C-G			Benign (Jun 15, 2019)
8-56074699-G-C			Benign (Jun 14, 2019)
8-56074746-C-G			Benign (Jun 15, 2019)
8-56074770-G-C			Benign (Jun 15, 2019)
8-56074788-T-A			Benign (Jun 15, 2019)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP