CHRM3-AS1

CHRM3 antisense RNA 1, the group of Antisense RNAs

Basic information

Region (hg38): 1:239898016-239953112

Links

ENSG00000234601 ∙ ∙ ∙ HGNC:40150 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the CHRM3-AS1 gene.

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the CHRM3-AS1 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding						0
Total	0	0	0	0	0

Variants in CHRM3-AS1

This is a list of pathogenic ClinVar variants found in the CHRM3-AS1 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
1-239907303-T-C			Benign (Nov 12, 2018)
1-239907453-T-G		Prune belly syndrome	Uncertain significance (Mar 11, 2024)
1-239907460-G-A			Likely benign (Mar 14, 2023)
1-239907463-C-T			Likely benign (May 09, 2024)
1-239907480-C-T		not specified	Uncertain significance (Feb 28, 2023)
1-239907514-A-G		not specified	Uncertain significance (Oct 01, 2024)
1-239907527-G-A		Prune belly syndrome	Uncertain significance (Mar 08, 2024)
1-239907543-C-G			Uncertain significance (Oct 17, 2022)
1-239907543-C-T		not specified	Uncertain significance (Dec 09, 2024)
1-239907544-G-A			Likely benign (Mar 27, 2022)
1-239907563-G-A		Prune belly syndrome	Uncertain significance (Mar 06, 2024)
1-239907563-G-C		Prune belly syndrome	Uncertain significance (May 22, 2024)
1-239907572-A-G		not specified	Uncertain significance (Aug 08, 2022)
1-239907573-A-G		Prune belly syndrome	Uncertain significance (May 13, 2024)
1-239907582-G-A		Prune belly syndrome	Uncertain significance (Jun 24, 2024)
1-239907610-C-T		CHRM3-related disorder	Benign (Apr 15, 2024)
1-239907615-C-T		not specified	Uncertain significance (Nov 10, 2024)
1-239907643-C-T		CHRM3-related disorder	Likely benign (Jun 28, 2024)
1-239907644-G-A			Benign (Jan 20, 2025)
1-239907665-G-A			Uncertain significance (Mar 13, 2022)
1-239907734-G-A		not specified • Prune belly syndrome	Uncertain significance (Jan 09, 2024)
1-239907779-C-T		Prune belly syndrome	Likely benign (Oct 22, 2024)
1-239907803-G-A		Prune belly syndrome	Pathogenic (Aug 04, 2020)
1-239907820-T-C			Likely benign (Apr 12, 2023)
1-239907835-C-T			Likely benign (Jun 15, 2018)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP