DAAM2-AS1

DAAM2 antisense RNA 1, the group of Antisense RNAs

Basic information

Region (hg38): 6:39848370-39900071

Links

ENSG00000235033 ∙ NCBI:100505635 ∙ ∙ HGNC:40830 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the DAAM2-AS1 gene.

• Inborn genetic diseases (14 variants)
• not provided (2 variants)
• Nephrotic syndrome, type 24 (2 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the DAAM2-AS1 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			16	1	1	18
Total	0	0	16	1	1

Variants in DAAM2-AS1

This is a list of pathogenic ClinVar variants found in the DAAM2-AS1 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
6-39856309-C-T		Inborn genetic diseases	Likely benign (May 20, 2024)
6-39856311-C-T		DAAM2-related disorder	Likely benign (Jun 14, 2024)
6-39856313-G-A		DAAM2-related disorder • Inborn genetic diseases	Uncertain significance (Jun 05, 2024)
6-39856313-G-T		Inborn genetic diseases	Uncertain significance (Jul 19, 2023)
6-39856322-G-A		Inborn genetic diseases	Uncertain significance (Oct 25, 2023)
6-39856329-T-C		DAAM2-related disorder	Benign (Feb 19, 2019)
6-39856347-C-G		Inborn genetic diseases	Uncertain significance (Oct 28, 2024)
6-39856353-C-T		DAAM2-related disorder	Benign (Feb 24, 2020)
6-39856354-G-A		DAAM2-related disorder	Benign (Mar 07, 2018)
6-39856384-C-T		Inborn genetic diseases	Uncertain significance (May 04, 2022)
6-39856431-G-A		DAAM2-related disorder	Likely benign (Apr 07, 2022)
6-39856434-C-T		DAAM2-related disorder	Likely benign (Jul 07, 2023)
6-39860967-T-C		Inborn genetic diseases	Uncertain significance (Dec 01, 2022)
6-39860979-C-A		Nephrotic syndrome, type 24 • DAAM2-related disorder	Uncertain significance (Feb 01, 2023)
6-39864446-C-T			Uncertain significance (Dec 01, 2016)
6-39864487-C-T		Inborn genetic diseases	Uncertain significance (May 26, 2022)
6-39864488-G-A		DAAM2-related disorder	Benign (May 24, 2019)
6-39865007-G-C		Nephrotic syndrome, type 24	Pathogenic (Apr 08, 2021)
6-39865015-G-T		DAAM2-related disorder	Likely benign (Sep 25, 2019)
6-39865058-C-T		Inborn genetic diseases	Uncertain significance (Nov 03, 2022)
6-39865059-G-A		Inborn genetic diseases	Uncertain significance (Jul 26, 2021)
6-39867500-T-C			Benign (Dec 31, 2019)
6-39867587-G-C		Inborn genetic diseases	Uncertain significance (Aug 04, 2023)
6-39867595-C-T		Inborn genetic diseases	Uncertain significance (Mar 06, 2023)
6-39867596-G-A		DAAM2-related disorder	Benign (Jul 30, 2019)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP