EEF1A1P5
pseudoeukaryotic translation elongation factor 1 alpha 1 pseudogene 5
Gene summary
Predicted to enable GTPase activity and translation elongation factor activity. Predicted to be involved in translational elongation. Located in extracellular exosome; nucleus; and obsolete extracellular space. [provided by Alliance of Genome Resources, Jun 2026]
- EEF1AL3
MANE transcript
Inheritance
ClinVar variants
Top phenotype
Max pathogenic AF
Genomic locus
External References & Databases
GenCC Phenotypes & Disease Associations
Curated gene-disease validity assertions and inheritance patterns
No GenCC data available for this gene.
ClinVar Associated Diseases & Phenotypes
Reported disease conditions connected to EEF1A1P5 variants in ClinVar
No annotated ClinVar phenotypes.
ClinVar Variants & Pathogenicity by Type
Statistics based on transcript . Only rare variants are included.
We include only reliable ClinVar variants with their consequences to MANE Select, MANE Plus Clinical transcripts, or transcripts with TSL equal to 1. Click a count to filter the variants table below.
Slight differences between displayed counts and ClinVar may occur due to a different transcript/consequence chosen by our variant effect predictor, or because we classify Benign/Likely benign as Likely benign and Pathogenic/Likely pathogenic as Likely pathogenic.
| Effect | PathogenicP | Likely pathogenicLP | VUS | Likely benignLB | BenignB | Sum |
|---|---|---|---|---|---|---|
| synonymous | 0 | |||||
| missense | 0 | |||||
| nonsense | 0 | |||||
| start loss | 0 | |||||
| frameshift | 0 | |||||
| splice donor/acceptor (+/-2bp) | 0 | |||||
| Total | 0 | 0 | 0 | 0 | 0 | 0 |
Transcript Catalog
Annotated transcript isoforms across RefSeq and Ensembl databases
| Transcript ID | Source | Protein ID | Coding Exons | MANE Status |
|---|---|---|---|---|
| No transcripts match your selected source or search query. | ||||
Gene Ontology (GO) Annotations & Pathways
Biological processes, molecular functions, cellular components and pathways
Pathways ConsensusPathDB
- Translation
- Metabolism of proteins
- Eukaryotic Translation Elongation
Biological Process
- translation
- translational elongation
- biological_process
Molecular Function
- molecular_function
- translation elongation factor activity
- GTPase activity
- GTP binding
Cellular Component
- extracellular space
- nucleus
- cytoplasm
- extracellular exosome
dbNSFP Gene Annotations
Source:
- Function
- FUNCTION: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. {ECO:0000250}.;
Recessive Scores
- pRec
- 0.649
Essentials
- Indispensability pred.
- E
- Indispensability score
- 0.539