EXOSC10-AS1

EXOSC10 antisense RNA 1, the group of Antisense RNAs

Basic information

Region (hg38): 1:11060228-11102105

Links

ENSG00000230337 ∙ NCBI:105376736 ∙ ∙ HGNC:40456 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the EXOSC10-AS1 gene.

• Inborn genetic diseases (1 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the EXOSC10-AS1 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)			1			1
splice region						0
non coding						0
Total	0	0	1	0	0

Variants in EXOSC10-AS1

This is a list of pathogenic ClinVar variants found in the EXOSC10-AS1 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
1-11066734-T-C		not specified	Uncertain significance (Sep 25, 2024)
1-11068021-C-T		not specified	Uncertain significance (May 24, 2024)
1-11068039-T-C		not specified	Uncertain significance (Nov 27, 2023)
1-11068042-T-G		not specified	Uncertain significance (Aug 28, 2023)
1-11068080-C-T		not specified	Uncertain significance (Jan 04, 2022)
1-11068691-T-C		not specified	Uncertain significance (Jan 23, 2023)
1-11069574-A-C		not specified	Uncertain significance (Mar 10, 2025)
1-11069598-G-C		not specified	Uncertain significance (Apr 22, 2024)
1-11069600-G-A		not specified	Uncertain significance (Feb 28, 2025)
1-11069610-T-C		not specified	Uncertain significance (Nov 20, 2024)
1-11070913-C-T			Likely benign (Apr 01, 2023)
1-11070917-C-T		not specified	Uncertain significance (Jan 18, 2023)
1-11070938-C-T		not specified	Likely benign (Jan 07, 2025)
1-11070943-T-C		not specified	Uncertain significance (Oct 06, 2023)
1-11072089-G-C		not specified	Uncertain significance (Apr 19, 2023)
1-11073927-C-T			Likely benign (Feb 01, 2024)
1-11073948-T-C			Likely benign (Jan 01, 2023)
1-11073972-G-C		not specified	Uncertain significance (Oct 27, 2022)
1-11073981-G-C		not specified	Uncertain significance (Mar 21, 2024)
1-11073987-G-A		not specified	Uncertain significance (Nov 11, 2024)
1-11074257-C-G		not specified	Uncertain significance (Jan 08, 2025)
1-11074272-C-T		not specified	Uncertain significance (Dec 15, 2023)
1-11076849-A-G		not specified	Uncertain significance (Oct 01, 2024)
1-11076852-G-A		not specified	Uncertain significance (Feb 01, 2025)
1-11076853-T-A		not specified	Uncertain significance (May 30, 2023)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP