GeneBe

FLICR

FOXP3 regulating long intergenic non-coding RNA, the group of Long non-coding RNAs with non-systematic symbols

Basic information

Region (hg38): X:49262866-49270521

Links

ENSG00000286181 ∙ NCBI:110437700 ∙ ∙ HGNC:53589 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the FLICR gene.

  • Insulin-dependent diabetes mellitus secretory diarrhea syndrome (1 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the FLICR gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type Pathogenic Likely pathogenic VUS Likely benign Benign Sum
synonymous
0
missense
0
nonsense
0
start loss
0
frameshift
0
inframe indel
0
splice donor/acceptor (+/-2bp)
0
splice region
0
non coding
1
clinvar
32
clinvar
2
clinvar
7
clinvar
 42
Total 1 0 32 2 7

Variants in FLICR

This is a list of pathogenic ClinVar variants found in the FLICR region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position Type Phenotype Significance ClinVar
X-49264507-C-CTAT not specified Benign (Jan 24, 2024)2688146
X-49264509-A-ATTT not specified Benign (Jan 24, 2024)2688117
X-49264512-A-ATTT not specified Benign (Jan 24, 2024)2688118
X-49264508-TATTATT-TATTATT Benign (Nov 11, 2018)1281014
X-49264657-T-C Insulin-dependent diabetes mellitus secretory diarrhea syndrome Uncertain significance (Feb 08, 2022)1521914
X-49264658-C-T Insulin-dependent diabetes mellitus secretory diarrhea syndrome Uncertain significance (May 06, 2022)2083959
X-49264660-C-A Insulin-dependent diabetes mellitus secretory diarrhea syndrome Pathogenic (Feb 27, 2017)691990
X-49264666-T-C FOXP3-related disorder Likely benign (Aug 28, 2019)3052581
X-49264711-G-A Uncertain significance (Aug 06, 2021)1677420
X-49264716-G-A not specified Benign (Dec 01, 2017)435253
X-49264839-G-A not specified Uncertain significance (Mar 06, 2020)1337568
X-49264991-C-G not specified Uncertain significance (Apr 18, 2016)435254
X-49269874-C-T Uncertain significance (Jun 17, 2024)3691028
X-49269909-T-C not specified Likely benign (Apr 07, 2023)2522159
X-49269927-G-A not specified Uncertain significance (Jun 22, 2021)2206056
X-49269946-C-T not specified Uncertain significance (Feb 22, 2023)2466821
X-49269958-C-T not specified Uncertain significance (Apr 07, 2023)2534488
X-49269997-C-A not specified Uncertain significance (Apr 17, 2024)3309475
X-49270036-C-G not specified Uncertain significance (Feb 12, 2025)2351800
X-49270040-G-T not specified Uncertain significance (Dec 07, 2023)3217683
X-49270053-GCGGGCAAGATGGCGGCGGCGGC-G Pathogenic (Dec 03, 2024)3679011
X-49270071-G-A not specified Uncertain significance (Aug 04, 2021)2347791
X-49270072-C-T not specified Uncertain significance (Feb 26, 2024)3217686
X-49270077-G-C not specified Uncertain significance (Nov 18, 2022)2328050
X-49270093-G-A not specified Uncertain significance (Apr 28, 2022)2359549

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP