FLNB-AS1

FLNB antisense RNA 1, the group of Antisense RNAs

Basic information

Region (hg38): 3:58162547-58170636

Links

ENSG00000244161 ∙ NCBI:105377105 ∙ ∙ HGNC:40239 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the FLNB-AS1 gene.

• not provided (2 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the FLNB-AS1 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding	2	1	74	73	16	166
Total	2	1	74	73	16

Variants in FLNB-AS1

This is a list of pathogenic ClinVar variants found in the FLNB-AS1 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
3-58163144-A-G			Likely benign (Feb 20, 2018)
3-58163146-TCTC-T			Likely benign (Sep 13, 2024)
3-58163150-C-T			Likely benign (Jun 03, 2023)
3-58163161-T-C			Likely benign (Mar 08, 2023)
3-58163161-T-G		Spondylocarpotarsal synostosis syndrome	not provided (-)
3-58163168-C-A		Inborn genetic diseases	Uncertain significance (Dec 12, 2024)
3-58163168-C-T		Inborn genetic diseases • Atelosteogenesis type I;Boomerang dysplasia;Atelosteogenesis type III;Spondylocarpotarsal synostosis syndrome;Larsen syndrome	Conflicting classifications of pathogenicity (Dec 24, 2024)
3-58163169-G-A			Likely benign (Jan 26, 2025)
3-58163170-C-T			Likely benign (Dec 27, 2021)
3-58163173-C-A		FLNB-Related Spectrum Disorders	Conflicting classifications of pathogenicity (Jan 29, 2025)
3-58163178-C-T		Inborn genetic diseases	Uncertain significance (Dec 15, 2023)
3-58163183-G-A			Uncertain significance (Jul 29, 2022)
3-58163189-G-C			Uncertain significance (Aug 20, 2024)
3-58163190-G-T			Uncertain significance (Jun 10, 2024)
3-58163192-G-A			Uncertain significance (May 19, 2023)
3-58163195-C-G			Uncertain significance (Dec 15, 2022)
3-58163197-C-T		FLNB-Related Spectrum Disorders	Conflicting classifications of pathogenicity (Oct 26, 2022)
3-58163203-C-T			Likely benign (Mar 31, 2023)
3-58163204-G-A			Uncertain significance (May 13, 2023)
3-58163224-C-T			Likely benign (Apr 12, 2022)
3-58163227-C-T			Likely benign (Dec 31, 2024)
3-58163228-G-A			Likely benign (Sep 06, 2024)
3-58163231-G-A		FLNB-Related Spectrum Disorders • not specified	Benign/Likely benign (Jan 23, 2025)
3-58163232-T-C			Uncertain significance (Jan 25, 2025)
3-58163238-G-T			Uncertain significance (Aug 29, 2022)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP