GRM5-AS1

GRM5 antisense RNA 1, the group of Antisense RNAs

Basic information

Region (hg38): 11:88504576-88524054

Links

ENSG00000255082 ∙ ∙ ∙ HGNC:40265 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the GRM5-AS1 gene.

• not provided (17 variants)
• Inborn genetic diseases (16 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the GRM5-AS1 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			17	13	3	33
Total	0	0	17	13	3

Variants in GRM5-AS1

This is a list of pathogenic ClinVar variants found in the GRM5-AS1 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
11-88508638-T-C		not specified	Uncertain significance (Oct 08, 2024)
11-88508707-G-A		not specified	Uncertain significance (Oct 22, 2024)
11-88508731-G-A		not specified	Uncertain significance (Oct 22, 2024)
11-88508754-C-G		not specified	Uncertain significance (Jun 30, 2024)
11-88508776-G-A		not specified	Uncertain significance (Feb 28, 2024)
11-88508785-T-G		not specified	Uncertain significance (Nov 15, 2021)
11-88508795-C-A			Likely benign (Jan 17, 2018)
11-88508809-C-T		not specified	Uncertain significance (Mar 08, 2024)
11-88508813-C-T		not specified	Uncertain significance (Jul 05, 2022)
11-88508815-G-A		not specified	Uncertain significance (Mar 17, 2023)
11-88508825-C-A		not specified	Uncertain significance (Oct 29, 2024)
11-88508843-C-T		not specified	Uncertain significance (Oct 19, 2024)
11-88508855-C-A		not specified	Uncertain significance (Dec 04, 2024)
11-88508859-C-G			Benign (Dec 31, 2019)
11-88508867-C-T		not specified	Uncertain significance (Jul 31, 2024)
11-88508877-C-T			Likely benign (Mar 28, 2018)
11-88508898-G-A			Likely benign (Jul 25, 2017)
11-88508912-T-C		not specified	Uncertain significance (Jan 05, 2022)
11-88508960-C-A		not specified	Uncertain significance (Dec 03, 2024)
11-88508975-T-G		not specified	Uncertain significance (Oct 22, 2021)
11-88508978-G-A		not specified	Uncertain significance (Aug 02, 2021)
11-88508984-C-T		not specified	Uncertain significance (Jun 11, 2024)
11-88508985-G-A			Likely benign (May 09, 2018)
11-88509031-C-T			Uncertain significance (Jan 04, 2021)
11-88509077-A-G		not specified	Uncertain significance (Mar 25, 2024)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP