HCG21

HLA complex group 21, the group of Long non-coding RNAs with non-systematic symbols

Basic information

Region (hg38): 6:30945979-30954862

Links

ENSG00000233529 ∙ ∙ ∙ HGNC:31335 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the HCG21 gene.

• Inborn genetic diseases (15 variants)
• not provided (7 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the HCG21 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			15	4	3	22
Total	0	0	15	4	3

Variants in HCG21

This is a list of pathogenic ClinVar variants found in the HCG21 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
6-30948556-C-T		not specified	Uncertain significance (Apr 27, 2022)
6-30948717-C-T		not specified	Uncertain significance (Jul 06, 2021)
6-30948735-C-T		not specified	Uncertain significance (Oct 12, 2021)
6-30948801-G-A		not specified	Uncertain significance (Dec 22, 2023)
6-30948844-A-G		not specified	Uncertain significance (Nov 08, 2022)
6-30948850-G-T		not specified	Uncertain significance (Aug 02, 2021)
6-30948867-C-T		not specified	Uncertain significance (Nov 03, 2023)
6-30948868-G-A			Benign (May 10, 2018)
6-30948895-A-C		not specified	Uncertain significance (Feb 22, 2023)
6-30948921-G-A		not specified	Uncertain significance (Dec 07, 2021)
6-30948933-C-A		not specified	Uncertain significance (Jun 07, 2023)
6-30948940-C-T		not specified	Uncertain significance (Sep 22, 2022)
6-30948970-G-A		not specified	Likely benign (Dec 08, 2023)
6-30949045-G-A		not specified	Uncertain significance (Mar 15, 2024)
6-30949069-G-A		not specified	Uncertain significance (Mar 07, 2024)
6-30949102-C-T		not specified	Uncertain significance (Nov 03, 2022)
6-30949185-G-A		not specified	Uncertain significance (Dec 09, 2023)
6-30949214-A-C		not specified	Uncertain significance (Apr 28, 2022)
6-30949224-A-G		not specified	Uncertain significance (Mar 02, 2023)
6-30949276-A-G		not specified	Uncertain significance (Jul 19, 2022)
6-30949317-C-G		not specified	Uncertain significance (Mar 19, 2024)
6-30949352-C-A		not specified	Uncertain significance (Nov 09, 2022)
6-30949363-C-A		not specified	Uncertain significance (Nov 16, 2021)
6-30949404-G-A		not specified	Uncertain significance (Apr 07, 2022)
6-30949420-C-A		not specified	Uncertain significance (Apr 09, 2024)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP