KIF23-AS1

KIF23 and PAQR5 antisense RNA 1, the group of Antisense RNAs

Basic information

Region (hg38): 15:69396897-69462856

Links

ENSG00000259426 ∙ NCBI:145694 ∙ ∙ HGNC:27075 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the KIF23-AS1 gene.

• not provided (3 variants)
• Inborn genetic diseases (3 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the KIF23-AS1 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			5		1	6
Total	0	0	5	0	1

Variants in KIF23-AS1

This is a list of pathogenic ClinVar variants found in the KIF23-AS1 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
15-69397475-G-A		not specified	Uncertain significance (Nov 09, 2022)
15-69397560-A-G		not specified	Uncertain significance (Jan 06, 2023)
15-69399974-C-G		not specified	Uncertain significance (Jan 10, 2023)
15-69403638-A-C		not specified	Uncertain significance (May 24, 2024)
15-69414437-C-T			Uncertain significance (Nov 10, 2021)
15-69414484-C-A			Uncertain significance (Jun 22, 2022)
15-69414493-C-G			Likely benign (Apr 07, 2023)
15-69414535-T-TGGGGGCAGGCGTCTCCACTCA			Benign (Oct 07, 2019)
15-69415975-T-A			Likely benign (Nov 08, 2022)
15-69415979-T-C			Likely benign (Aug 17, 2022)
15-69415990-C-CCA			Uncertain significance (Jan 02, 2024)
15-69416009-C-T			Likely benign (Jul 06, 2018)
15-69416039-A-G			Likely benign (Jul 10, 2023)
15-69416041-C-T		KIF23-related disorder	Uncertain significance (Dec 30, 2023)
15-69416045-C-A			Uncertain significance (Nov 29, 2022)
15-69416045-C-T			Likely benign (Nov 01, 2022)
15-69416058-G-A			Uncertain significance (Apr 04, 2023)
15-69416069-G-A		KIF23-related disorder	Benign (Jan 29, 2024)
15-69417347-G-A			Benign (Jul 09, 2018)
15-69417385-A-G			Benign (Nov 07, 2023)
15-69417390-G-A		not specified	Uncertain significance (Jul 26, 2022)
15-69417390-G-T		not specified	Uncertain significance (Sep 26, 2023)
15-69417401-C-A		not specified	Conflicting classifications of pathogenicity (Dec 27, 2023)
15-69417409-C-A			Benign (Jan 31, 2024)
15-69417422-G-A		not specified	Uncertain significance (Dec 16, 2023)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP