LIMASI

lncRNA inflammatory and mucous response associated, antisense to ICAM1, the group of Long non-coding RNAs with non-systematic symbols

Basic information

Region (hg38): 19:10239048-10290813

Links

ENSG00000266978 ∙ NCBI:105372272 ∙ ∙ HGNC:56357 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the LIMASI gene.

• Inborn genetic diseases (22 variants)
• not provided (13 variants)
• not specified (2 variants)
• Malaria, susceptibility to (2 variants)
• Malaria, cerebral, susceptibility to (1 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the LIMASI gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			23	9	7	39
Total	0	0	23	9	7

Variants in LIMASI

This is a list of pathogenic ClinVar variants found in the LIMASI region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
19-10252458-G-A		not specified	Uncertain significance (Jul 06, 2021)
19-10256781-G-C		not specified	Uncertain significance (Jun 11, 2021)
19-10258285-G-A		not specified	Uncertain significance (Jul 09, 2021)
19-10258452-G-A		not specified	Uncertain significance (Jul 14, 2021)
19-10259604-A-C		not specified	Benign (Mar 29, 2016)
19-10259609-G-C		not specified	Benign (Mar 29, 2016)
19-10271151-A-C		ICAM1-related disorder	Benign (Dec 05, 2019)
19-10274815-C-T		Malaria, susceptibility to	Uncertain significance (Jul 12, 2022)
19-10274827-G-A		not specified	Uncertain significance (May 15, 2023)
19-10274844-C-T			Likely benign (Jul 12, 2018)
19-10274859-G-A		ICAM1-related disorder	Likely benign (Nov 16, 2019)
19-10274864-A-T		Malaria, cerebral, susceptibility to • ICAM1-related disorder	Benign; risk factor (Dec 05, 2019)
19-10274921-A-G		not specified	Uncertain significance (Apr 12, 2023)
19-10274989-G-C		not specified	Uncertain significance (Oct 20, 2023)
19-10283477-G-A			Likely benign (Mar 01, 2022)
19-10283515-C-G			Likely benign (Jun 13, 2018)
19-10283549-C-A		not specified	Uncertain significance (Dec 13, 2023)
19-10283549-C-T		not specified	Uncertain significance (Mar 27, 2023)
19-10283565-G-A		not specified	Uncertain significance (Dec 06, 2021)
19-10283591-G-A		not specified	Uncertain significance (Oct 22, 2021)
19-10283603-C-T		not specified	Uncertain significance (Feb 28, 2023)
19-10283648-G-T		not specified	Uncertain significance (May 31, 2023)
19-10283652-A-C		not specified	Uncertain significance (Feb 02, 2022)
19-10283664-C-T		not specified	Uncertain significance (Apr 20, 2023)
19-10283688-A-G		not specified	Uncertain significance (Jul 19, 2022)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP