LINC01018

long intergenic non-protein coding RNA 1018, the group of Long intergenic non-protein coding RNAs

Basic information

Region (hg38): 5:6582135-6613722

Links

ENSG00000250056 ∙ NCBI:255167 ∙ OMIM:616385 ∙ HGNC:27394 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the LINC01018 gene.

• Intellectual disability, autosomal recessive 5 (36 variants)
• not provided (35 variants)
• Inborn genetic diseases (26 variants)
• not specified (12 variants)
• Intellectual disability (1 variants)
• Intellectual Disability, Recessive (1 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the LINC01018 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding		1	39	28	5	73
Total	0	1	39	28	5

Variants in LINC01018

This is a list of pathogenic ClinVar variants found in the LINC01018 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
5-6599304-A-T		Intellectual disability, autosomal recessive 5	Uncertain significance (Jan 13, 2018)
5-6599307-C-T		Intellectual disability, autosomal recessive 5	Uncertain significance (Jan 13, 2018)
5-6599345-A-G		Intellectual disability, autosomal recessive 5	Benign (Jan 12, 2018)
5-6599363-G-A		Intellectual disability, autosomal recessive 5	Benign (Jan 12, 2018)
5-6599379-TG-T		Intellectual Disability, Recessive	Likely benign (Jun 14, 2016)
5-6599394-T-C		Intellectual disability, autosomal recessive 5	Uncertain significance (Feb 16, 2018)
5-6599537-T-C		Intellectual disability, autosomal recessive 5	Uncertain significance (Jan 13, 2018)
5-6599632-G-C		Intellectual disability, autosomal recessive 5	Uncertain significance (Jan 13, 2018)
5-6599724-G-A		Intellectual disability, autosomal recessive 5	Uncertain significance (Jan 12, 2018)
5-6599786-A-G		Intellectual disability, autosomal recessive 5	Uncertain significance (Jan 13, 2018)
5-6599827-C-T		Intellectual disability, autosomal recessive 5	Benign (Sep 11, 2018)
5-6599829-G-T		Intellectual disability, autosomal recessive 5	Uncertain significance (Jan 13, 2018)
5-6599841-C-T		Intellectual disability, autosomal recessive 5	Uncertain significance (Jan 13, 2018)
5-6599876-A-C		Intellectual disability, autosomal recessive 5	Benign/Likely benign (Nov 02, 2018)
5-6599878-G-A		Intellectual disability, autosomal recessive 5	Uncertain significance (Jan 13, 2018)
5-6599904-GCCCCCGCTGCCTTGGGCCTGCTCACCGGGGTGGATGGA-G			Uncertain significance (Jul 12, 2018)
5-6599909-C-T		Intellectual disability, autosomal recessive 5	Likely benign (Jan 13, 2018)
5-6599910-G-A		Intellectual disability, autosomal recessive 5	Uncertain significance (Jan 13, 2018)
5-6599930-C-T		not specified • Intellectual disability, autosomal recessive 5 • Inborn genetic diseases • NSUN2-related disorder	Conflicting classifications of pathogenicity (Jul 01, 2024)
5-6599940-G-T			Uncertain significance (Apr 23, 2023)
5-6599947-C-T		Intellectual disability, autosomal recessive 5	Conflicting classifications of pathogenicity (Nov 01, 2023)
5-6599948-G-A		Intellectual disability, autosomal recessive 5 • Inborn genetic diseases	Uncertain significance (Dec 20, 2023)
5-6599948-G-T		Inborn genetic diseases	Uncertain significance (Dec 27, 2016)
5-6599950-C-G		not specified	Likely benign (Jan 04, 2016)
5-6599950-C-T			Likely benign (Jun 27, 2022)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP