LINC02289

long intergenic non-protein coding RNA 2289, the group of Long intergenic non-protein coding RNAs

Basic information

Region (hg38): 14:76959805-77086457

Links

ENSG00000258819 ∙ NCBI:102724190 ∙ ∙ HGNC:53205 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the LINC02289 gene.

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the LINC02289 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding						0
Total	0	0	0	0	0

Variants in LINC02289

This is a list of pathogenic ClinVar variants found in the LINC02289 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
14-77025406-G-A		IRF2BPL-related disorder	Uncertain significance (Aug 04, 2023)
14-77025413-TCTC-T			Uncertain significance (Nov 22, 2022)
14-77025439-G-A		Inborn genetic diseases	Uncertain significance (Jun 01, 2023)
14-77025448-G-A			Uncertain significance (Dec 18, 2019)
14-77025484-T-C			Uncertain significance (Mar 10, 2020)
14-77025494-C-G		IRF2BPL-related disorder • Inborn genetic diseases	Uncertain significance (Aug 09, 2021)
14-77025505-T-C		Inborn genetic diseases	Uncertain significance (Feb 05, 2024)
14-77025531-G-T			Likely benign (Feb 01, 2024)
14-77025555-ACT-A			Likely pathogenic (Aug 01, 2019)
14-77025571-G-C			Uncertain significance (Feb 09, 2024)
14-77025573-G-A			Likely benign (Sep 01, 2023)
14-77025587-G-T			Uncertain significance (Feb 22, 2024)
14-77025589-C-A		Rare genetic intellectual disability	Uncertain significance (-)
14-77025590-T-A		IRF2BPL-related disorder	Likely benign (Jul 01, 2024)
14-77025593-G-A		Neurodevelopmental disorder with regression, abnormal movements, loss of speech, and seizures • IRF2BPL-related disorder	Uncertain significance (Sep 17, 2023)
14-77025596-C-A			Uncertain significance (Dec 18, 2023)
14-77025632-GT-G		Neurodevelopmental disorder with regression, abnormal movements, loss of speech, and seizures	Pathogenic (Nov 29, 2022)
14-77025640-CA-C		Inborn genetic diseases	Likely pathogenic (Nov 14, 2017)
14-77025654-GA-G			Pathogenic (Dec 01, 2020)
14-77025655-AG-A		Neurodevelopmental disorder with regression, abnormal movements, loss of speech, and seizures	Likely pathogenic (Aug 25, 2022)
14-77025655-A-AGG		Neurodevelopmental disorder with regression, abnormal movements, loss of speech, and seizures	Likely pathogenic (Sep 27, 2022)
14-77025657-G-GAC		Neurodevelopmental disorder with regression, abnormal movements, loss of speech, and seizures	Pathogenic (Jul 02, 2020)
14-77025670-G-C			Uncertain significance (Nov 27, 2023)
14-77025670-GC-G		IRF2BPL-related disorder	Pathogenic/Likely pathogenic (May 20, 2022)
14-77025672-C-G			Uncertain significance (Jan 24, 2023)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP