MIAT

myocardial infarction associated transcript, the group of Long non-coding RNAs with non-systematic symbols

Basic information

Region (hg38): 22:26646411-26676478

Previous symbols: [ "C22orf35" ]

Links

ENSG00000225783 ∙ NCBI:440823 ∙ OMIM:611082 ∙ HGNC:33425 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the MIAT gene.

• not provided (2 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the MIAT gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding					2	2
Total	0	0	0	0	2

Variants in MIAT

This is a list of pathogenic ClinVar variants found in the MIAT region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
22-26666332-G-A		MIAT-related disorder	Benign (Aug 14, 2019)
22-26666628-G-A		MIAT-related disorder	Benign (Sep 24, 2019)
22-26666705-G-A		MIAT-related disorder	Benign (Jan 28, 2020)
22-26666790-G-T		MIAT-related disorder	Benign (Mar 18, 2019)
22-26669771-G-C		MIAT-related disorder	Benign (May 08, 2019)
22-26669882-G-C		MIAT-related disorder	Likely benign (Jun 07, 2023)
22-26670056-A-AT		MIAT-related disorder	Benign (Jan 27, 2020)
22-26670601-T-TTAAA		MIAT-related disorder	Likely benign (Feb 21, 2023)
22-26670771-T-C			Benign (Jun 01, 2023)
22-26671260-G-T		MIAT-related disorder	Benign (Jul 25, 2019)
22-26671828-C-T		MIAT-related disorder	Benign (Sep 17, 2019)
22-26672088-A-T		MIAT-related disorder	Benign (Aug 26, 2019)
22-26672189-C-T		MIAT-related disorder	Benign (Nov 25, 2019)
22-26673290-G-T		MIAT-related disorder	Benign (Feb 19, 2020)
22-26674290-T-C			Benign (Dec 01, 2022)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP

Mouse Genome Informatics

• Gene name: Miat