MIR21

microRNA 21, the group of MicroRNAs

Basic information

Region (hg38): 17:59841266-59841337

Previous symbols: [ "MIRN21" ]

Links

ENSG00000284190

∙ NCBI:406991 ∙ OMIM:611020 ∙ HGNC:31586 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the MIR21 gene.

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the MIR21 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding						0
Total	0	0	0	0	0

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP

Pathway: Proteoglycans in cancer - Homo sapiens (human);MicroRNAs in cancer - Homo sapiens (human);miRNA Regulation of DNA Damage Response;MicroRNAs in cardiomyocyte hypertrophy;miRNAs involved in DNA damage response;TFs Regulate miRNAs related to cardiac hypertrophy;Integrated Cancer Pathway;Integrated Breast Cancer Pathway;miR-targeted genes in epithelium - TarBase;miR-targeted genes in lymphocytes - TarBase;miR-targeted genes in muscle cell - TarBase;miR-targeted genes in squamous cell - TarBase;Alzheimers Disease;Signaling Pathways in Glioblastoma;Androgen Receptor Network in Prostate Cancer;Retinoblastoma (RB) in Cancer;Integrated Lung Cancer Pathway;Pathways in clear cell renal cell carcinoma;ErbB Signaling Pathway (Consensus)