MIR497HG

mir-497-195 cluster host gene, the group of MicroRNA non-coding host genes

Basic information

Region (hg38): 17:6875220-7022133

Links

ENSG00000267532 ∙ NCBI:100506755 ∙ ∙ HGNC:39523 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the MIR497HG gene.

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the MIR497HG gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding						0
Total	0	0	0	0	0

Variants in MIR497HG

This is a list of pathogenic ClinVar variants found in the MIR497HG region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
17-6995799-C-T			Benign (Nov 10, 2018)
17-6995902-G-A			Benign (Nov 10, 2018)
17-6996178-C-A		not specified	Uncertain significance (Feb 28, 2024)
17-6996240-C-G			Benign (Nov 10, 2018)
17-6996310-C-T			Benign (Nov 10, 2018)
17-6996412-T-C			Benign (Jun 18, 2021)
17-6996757-G-A			Benign (Nov 10, 2018)
17-6996897-C-A		not specified	Uncertain significance (Oct 30, 2023)
17-6996913-G-A		not specified	Uncertain significance (Oct 24, 2023)
17-6996965-T-C		not specified	Likely benign (May 04, 2022)
17-6997043-C-T			Benign (Nov 10, 2018)
17-6997064-T-C			Benign (Jun 18, 2021)
17-6997125-T-G			Benign (Nov 10, 2018)
17-6998353-G-A			Benign (Nov 10, 2018)
17-6998511-C-T		not specified	Uncertain significance (Aug 09, 2021)
17-6998512-G-A		not specified	Uncertain significance (Dec 26, 2023)
17-6998520-G-C			Likely benign (Apr 01, 2022)
17-6998566-T-G		not specified	Uncertain significance (Apr 18, 2023)
17-6998570-A-C			Likely benign (Jul 01, 2024)
17-6998575-G-A		not specified	Uncertain significance (Jan 31, 2023)
17-6998836-G-A		not specified	Uncertain significance (Oct 03, 2023)
17-6998860-G-A			Benign (Nov 10, 2018)
17-6998958-T-C		not specified	Uncertain significance (Jan 19, 2024)
17-6998976-G-A			Benign (Apr 24, 2018)
17-6998981-T-C		not specified	Uncertain significance (Nov 09, 2023)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP

Essentials

• gene_indispensability_pred: N
• gene_indispensability_score: 0.114