MIR6084

microRNA 6084, the group of MicroRNAs

Basic information

Region (hg38): 1:20633679-20633788

Links

ENSG00000284005 ∙ NCBI:102464833 ∙ ∙ HGNC:50235 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the MIR6084 gene.

• Autosomal recessive early-onset Parkinson disease 6 (15 variants)
• not provided (4 variants)
• Inborn genetic diseases (4 variants)
• not specified (1 variants)
• See cases (1 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the MIR6084 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			14	4	1	19
Total	0	0	14	4	1

Variants in MIR6084

This is a list of pathogenic ClinVar variants found in the MIR6084 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
1-20633687-G-C		Autosomal recessive early-onset Parkinson disease 6 • See cases • Inborn genetic diseases	Uncertain significance (May 16, 2022)
1-20633689-C-G		Autosomal recessive early-onset Parkinson disease 6	Likely benign (Dec 12, 2023)
1-20633701-A-G		Autosomal recessive early-onset Parkinson disease 6	Likely benign (Aug 03, 2023)
1-20633703-C-T			Uncertain significance (Jul 17, 2018)
1-20633706-G-A		Autosomal recessive early-onset Parkinson disease 6	Uncertain significance (Mar 01, 2022)
1-20633709-C-A		Autosomal recessive early-onset Parkinson disease 6	Uncertain significance (Nov 04, 2019)
1-20633713-G-A		Autosomal recessive early-onset Parkinson disease 6	Conflicting classifications of pathogenicity (Nov 12, 2023)
1-20633717-C-T			Uncertain significance (Aug 01, 2016)
1-20633717-C-CGCAGGG		Autosomal recessive early-onset Parkinson disease 6	Uncertain significance (Aug 17, 2022)
1-20633721-G-A		Autosomal recessive early-onset Parkinson disease 6 • Inborn genetic diseases	Uncertain significance (Feb 21, 2024)
1-20633725-C-T		Autosomal recessive early-onset Parkinson disease 6	Likely benign (Dec 15, 2021)
1-20633732-G-C		Autosomal recessive early-onset Parkinson disease 6 • Inborn genetic diseases	Uncertain significance (Jul 11, 2022)
1-20633737-C-T		not specified • Autosomal recessive early-onset Parkinson disease 6	Benign (Jul 31, 2024)
1-20633744-C-T		Inborn genetic diseases	Uncertain significance (Jun 24, 2022)
1-20633747-C-T		Autosomal recessive early-onset Parkinson disease 6	Uncertain significance (Apr 12, 2022)
1-20633750-C-T		Autosomal recessive early-onset Parkinson disease 6	Uncertain significance (Jul 31, 2022)
1-20633751-GC-CT		Autosomal recessive early-onset Parkinson disease 6	Uncertain significance (Jan 24, 2024)
1-20633766-C-T		Autosomal recessive early-onset Parkinson disease 6	Uncertain significance (Apr 22, 2023)
1-20633771-G-T		Inborn genetic diseases	Uncertain significance (Aug 17, 2021)
1-20633789-T-C			Likely benign (Dec 01, 2022)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP