MIR6766

microRNA 6766, the group of MicroRNAs

Basic information

Region (hg38): 15:89326739-89326810

Links

ENSG00000275101 ∙ NCBI:102466983 ∙ ∙ HGNC:49941 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the MIR6766 gene.

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the MIR6766 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding						0
Total	0	0	0	0	0

Variants in MIR6766

This is a list of pathogenic ClinVar variants found in the MIR6766 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
15-89326742-TG-T		not specified • Progressive sclerosing poliodystrophy • Hereditary spastic paraplegia • 6 conditions • Inborn genetic diseases	Benign/Likely benign (Feb 01, 2024)
15-89326743-G-A		Progressive sclerosing poliodystrophy • POLG-related disorder	Likely benign (Jan 31, 2024)
15-89326743-G-C		Progressive sclerosing poliodystrophy	Likely benign (Oct 15, 2023)
15-89326744-A-T		Progressive sclerosing poliodystrophy	Likely benign (Jul 19, 2023)
15-89326746-G-T		Progressive sclerosing poliodystrophy	Likely benign (Oct 24, 2023)
15-89326747-G-A		Progressive sclerosing poliodystrophy	Likely benign (Aug 02, 2023)
15-89326748-T-C		Progressive sclerosing poliodystrophy	Likely benign (Jan 14, 2024)
15-89326748-T-G		Progressive sclerosing poliodystrophy	Likely benign (Jan 31, 2024)
15-89326749-G-A		Progressive sclerosing poliodystrophy	Likely benign (Dec 09, 2023)
15-89326749-G-C		Progressive sclerosing poliodystrophy	Likely benign (Jul 21, 2021)
15-89326749-G-T		Progressive sclerosing poliodystrophy	Likely benign (Jul 04, 2021)
15-89326752-G-A		Progressive sclerosing poliodystrophy	Likely benign (Aug 28, 2023)
15-89326754-A-G		Progressive sclerosing poliodystrophy	Likely benign (Aug 20, 2022)
15-89326756-G-A		Progressive sclerosing poliodystrophy	Likely benign (Apr 06, 2023)
15-89326758-C-T		Progressive sclerosing poliodystrophy	Likely benign (Dec 22, 2023)
15-89326759-A-C		Progressive sclerosing poliodystrophy	Likely benign (Oct 01, 2018)
15-89326768-CAGG-C		Progressive sclerosing poliodystrophy	Likely benign (Oct 01, 2018)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP