NCK1-DT

NCK1 divergent transcript, the group of Divergent transcripts

Basic information

Region (hg38): 3:136807637-136862618

Previous symbols: [ "NCK1-AS1" ]

Links

ENSG00000239213 ∙ NCBI:101927597 ∙ ∙ HGNC:49645 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the NCK1-DT gene.

• Inborn genetic diseases (11 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the NCK1-DT gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			11			11
Total	0	0	11	0	0

Variants in NCK1-DT

This is a list of pathogenic ClinVar variants found in the NCK1-DT region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
3-136854491-G-A		not specified	Uncertain significance (Jan 31, 2023)
3-136854528-T-C		not specified	Uncertain significance (Feb 22, 2023)
3-136854578-G-A		not specified	Uncertain significance (Apr 26, 2024)
3-136854593-T-C		not specified	Uncertain significance (Mar 16, 2024)
3-136854608-G-A		not specified	Uncertain significance (Sep 09, 2024)
3-136854614-A-T		not specified	Uncertain significance (Apr 09, 2024)
3-136854624-A-G		not specified	Uncertain significance (Nov 21, 2022)
3-136854648-A-C		not specified	Uncertain significance (Jan 04, 2022)
3-136854681-C-A		not specified	Uncertain significance (Oct 09, 2024)
3-136854689-C-T		not specified	Uncertain significance (Jul 14, 2021)
3-136854707-A-G		not specified	Uncertain significance (Mar 02, 2023)
3-136854725-C-A		not specified	Uncertain significance (Feb 14, 2024)
3-136854911-G-T		not specified	Uncertain significance (Nov 08, 2024)
3-136854958-A-C		not specified	Uncertain significance (May 25, 2022)
3-136855022-A-G		not specified	Uncertain significance (Aug 02, 2021)
3-136855131-C-T		not specified	Uncertain significance (Nov 17, 2022)
3-136855183-T-G		not specified	Uncertain significance (Oct 25, 2023)
3-136855207-A-T		not specified	Uncertain significance (Jun 18, 2021)
3-136855214-T-C		not specified	Uncertain significance (Nov 08, 2024)
3-136855473-C-G		not specified	Uncertain significance (Nov 21, 2023)
3-136855514-C-A		not specified	Uncertain significance (Oct 27, 2022)
3-136855524-T-C		not specified	Uncertain significance (Apr 23, 2024)
3-136855553-G-A		not specified	Uncertain significance (Dec 27, 2022)
3-136855664-G-A		not specified	Uncertain significance (Jun 04, 2024)
3-136855689-C-T		not specified	Uncertain significance (Mar 07, 2024)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP