NGFR-AS1

NGFR antisense RNA 1, the group of Antisense RNAs

Basic information

Region (hg38): 17:49505657-49577962

Links

ENSG00000249906 ∙ NCBI:100288866 ∙ ∙ HGNC:55555 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the NGFR-AS1 gene.

• Inborn genetic diseases (21 variants)
• not provided (10 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the NGFR-AS1 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)			1			1
splice region						0
non coding			20	5	5	30
Total	0	0	21	5	5

Variants in NGFR-AS1

This is a list of pathogenic ClinVar variants found in the NGFR-AS1 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
17-49506317-T-C		not specified	Uncertain significance (Aug 27, 2024)
17-49506408-G-A			Likely benign (Mar 30, 2018)
17-49506412-C-T		not specified	Uncertain significance (Jul 05, 2024)
17-49506418-G-T		not specified	Uncertain significance (Nov 10, 2022)
17-49506423-C-T			Benign (Mar 29, 2018)
17-49506438-T-A		not specified	Uncertain significance (Apr 01, 2022)
17-49506475-G-A		not specified	Uncertain significance (Aug 16, 2021)
17-49506485-C-T			Benign (Jul 10, 2018)
17-49506500-C-G		not specified	Uncertain significance (Oct 12, 2021)
17-49506568-C-T		not specified	Uncertain significance (Jul 02, 2024)
17-49506586-C-T		not specified	Uncertain significance (Jul 02, 2024)
17-49506604-G-C		not specified	Uncertain significance (Jun 24, 2022)
17-49506623-G-T		not specified	Uncertain significance (Dec 15, 2022)
17-49506634-C-T		not specified	Uncertain significance (Oct 26, 2022)
17-49506643-G-A		not specified	Uncertain significance (Feb 22, 2023)
17-49506655-G-C		not specified	Uncertain significance (Oct 26, 2022)
17-49506667-G-A			Likely benign (Apr 24, 2018)
17-49510435-C-T		not specified	Uncertain significance (May 23, 2023)
17-49510444-C-G		not specified	Uncertain significance (Jul 12, 2022)
17-49510471-C-T		not specified	Uncertain significance (Feb 15, 2023)
17-49510473-C-T			Likely benign (Apr 10, 2018)
17-49510478-C-A		not specified	Uncertain significance (Aug 04, 2024)
17-49510577-G-A		not specified	Uncertain significance (Nov 08, 2022)
17-49510580-G-C		not specified	Uncertain significance (Nov 24, 2024)
17-49510583-C-T		not specified	Uncertain significance (May 30, 2024)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP