SHROOM3-AS1

SHROOM3 antisense RNA 1, the group of Antisense RNAs

Basic information

Region (hg38): 4:76624149-76802480

Links

ENSG00000233860 ∙ NCBI:105377289 ∙ ∙ HGNC:41265 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the SHROOM3-AS1 gene.

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the SHROOM3-AS1 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			161	29	25	215
Total	0	0	161	29	25

Variants in SHROOM3-AS1

This is a list of pathogenic ClinVar variants found in the SHROOM3-AS1 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
4-76710205-G-A		not specified	Likely benign (Aug 07, 2024)
4-76710233-C-A		not specified	Uncertain significance (Feb 26, 2024)
4-76710238-C-T		not specified	Uncertain significance (Oct 26, 2022)
4-76710250-G-A		not specified	Uncertain significance (Dec 27, 2022)
4-76710272-T-A		SHROOM3-related disorder	Benign (Nov 12, 2018)
4-76710274-C-T		not specified	Uncertain significance (Aug 27, 2024)
4-76730904-G-C		SHROOM3-related disorder	Benign (May 22, 2019)
4-76731066-T-C			Benign (Jun 19, 2021)
4-76738783-A-C		not specified	Uncertain significance (Dec 19, 2022)
4-76738785-C-G		not specified	Uncertain significance (Nov 07, 2024)
4-76738789-G-A		not specified	Uncertain significance (Jan 23, 2025)
4-76738792-C-T		SHROOM3-related disorder	Benign (Jul 12, 2019)
4-76738808-G-A		not specified	Uncertain significance (Oct 05, 2021)
4-76738820-A-G		not specified	Likely benign (Apr 22, 2022)
4-76738870-C-A		SHROOM3-related disorder	Likely benign (Mar 18, 2022)
4-76738903-G-A		not specified	Likely benign (Aug 08, 2022)
4-76738921-A-T		not specified	Uncertain significance (Apr 11, 2023)
4-76738940-G-A		not specified	Uncertain significance (Dec 06, 2022)
4-76738995-C-A		not specified	Uncertain significance (Jun 21, 2023)
4-76739009-G-C		not specified • SHROOM3-related disorder	Benign (Nov 12, 2018)
4-76739018-G-A		not specified	Uncertain significance (Sep 10, 2024)
4-76739029-A-G		not specified	Uncertain significance (Apr 10, 2023)
4-76739063-A-C		not specified	Uncertain significance (Apr 07, 2023)
4-76739070-G-A		not specified	Uncertain significance (May 01, 2024)
4-76739117-G-C		not specified	Uncertain significance (Nov 24, 2024)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP