SLIT3-AS2

SLIT3 antisense RNA 2, the group of Antisense RNAs

Basic information

Region (hg38): 5:168706567-168720884

Links

ENSG00000254042 ∙ NCBI:101927969 ∙ ∙ HGNC:40551 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the SLIT3-AS2 gene.

• not provided (6 variants)
• Inborn genetic diseases (2 variants)
• SLIT3-related anomalies of the kidney and urinary tract (1 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the SLIT3-AS2 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			3	3	3	9
Total	0	0	3	3	3

Variants in SLIT3-AS2

This is a list of pathogenic ClinVar variants found in the SLIT3-AS2 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
5-168708015-A-G			Likely benign (Feb 01, 2023)
5-168708094-A-C		not specified	Uncertain significance (Apr 04, 2024)
5-168710886-G-A			Benign (Jul 04, 2018)
5-168710911-G-T		not specified	Uncertain significance (Oct 08, 2024)
5-168710938-G-C		not specified	Uncertain significance (Aug 05, 2024)
5-168710960-C-T		not specified	Uncertain significance (Jan 23, 2024)
5-168710971-G-A			Likely benign (Feb 01, 2023)
5-168710993-G-A		not specified	Uncertain significance (Jun 09, 2022)
5-168711047-G-T		not specified	Uncertain significance (Nov 11, 2024)
5-168711055-C-T			Likely benign (Dec 01, 2022)
5-168712274-G-A			Benign (May 18, 2018)
5-168712305-C-T			Benign (Aug 16, 2018)
5-168712307-T-C		not specified	Uncertain significance (Aug 04, 2021)
5-168720289-T-C		SLIT3-related anomalies of the kidney and urinary tract	Uncertain significance (Dec 13, 2022)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP