SNHG29

small nucleolar RNA host gene 29, the group of Small nucleolar RNA non-coding host genes

Basic information

Region (hg38): 17:16438767-16480249

Previous symbols: [ "C17orf45", "NCRNA00188", "C17orf76-AS1", "FAM211A-AS1", "LRRC75A-AS1" ]

Links

ENSG00000175061 ∙ NCBI:125144 ∙ ∙ HGNC:28619 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the SNHG29 gene.

• Inborn genetic diseases (10 variants)
• not provided (2 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the SNHG29 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			8	3	1	12
Total	0	0	8	3	1

Variants in SNHG29

This is a list of pathogenic ClinVar variants found in the SNHG29 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
17-16443644-C-T		not specified	Uncertain significance (Sep 29, 2023)
17-16443686-C-T		not specified	Uncertain significance (May 24, 2023)
17-16443758-A-G		not specified	Uncertain significance (Oct 12, 2024)
17-16443766-C-T		not specified	Uncertain significance (Jan 23, 2023)
17-16443796-G-C		not specified	Uncertain significance (Nov 23, 2024)
17-16443809-C-T		not specified	Uncertain significance (Jul 25, 2024)
17-16443866-T-C		not specified	Uncertain significance (Oct 13, 2023)
17-16443887-C-T		not specified	Uncertain significance (Jun 28, 2024)
17-16443894-G-T		not specified	Likely benign (Feb 13, 2024)
17-16443901-C-T		not specified	Uncertain significance (May 02, 2024)
17-16443931-C-T			Benign (Dec 20, 2017)
17-16443936-C-T		not specified	Likely benign (Dec 16, 2023)
17-16444060-C-T		not specified	Uncertain significance (Jul 13, 2021)
17-16444065-G-A		not specified	Likely benign (May 24, 2023)
17-16444100-C-T		not specified	Uncertain significance (Dec 14, 2022)
17-16444102-G-T		not specified	Uncertain significance (Jun 07, 2023)
17-16447876-G-A		not specified	Uncertain significance (Mar 29, 2022)
17-16447923-C-T		not specified	Uncertain significance (Feb 26, 2024)
17-16447942-C-T		not specified	Likely benign (Mar 27, 2023)
17-16447957-C-T		not specified	Uncertain significance (Nov 17, 2023)
17-16462259-G-A		not specified	Uncertain significance (Aug 12, 2024)
17-16462272-G-A		not specified	Uncertain significance (Jan 26, 2023)
17-16462280-C-T		not specified	Uncertain significance (Oct 20, 2024)
17-16462303-G-A			Likely benign (Aug 01, 2022)
17-16462328-C-T		not specified	Uncertain significance (May 26, 2023)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP

Haploinsufficiency Scores

• pHI: 0.0120