SNHG6

small nucleolar RNA host gene 6, the group of Small nucleolar RNA non-coding host genes

Basic information

Region (hg38): 8:66895990-66926525

Links

ENSG00000245910 ∙ NCBI:641638 ∙ OMIM:612215 ∙ HGNC:32965 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the SNHG6 gene.

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the SNHG6 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding						0
Total	0	0	0	0	0

Variants in SNHG6

This is a list of pathogenic ClinVar variants found in the SNHG6 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
8-66896177-G-T		not specified	Uncertain significance (Jan 24, 2024)
8-66896253-C-T		Male infertility with azoospermia or oligozoospermia due to single gene mutation	Likely pathogenic (Sep 01, 2023)
8-66896795-C-G		not specified	Uncertain significance (Jun 14, 2023)
8-66896811-A-G		not specified	Uncertain significance (Aug 15, 2023)
8-66896826-T-C		not specified	Uncertain significance (May 30, 2024)
8-66896897-A-G		not specified	Uncertain significance (Aug 12, 2021)
8-66896903-C-T			Benign (Dec 31, 2019)
8-66896909-G-C		not specified	Uncertain significance (Jan 31, 2025)
8-66896939-A-G		not specified	Uncertain significance (Jun 29, 2023)
8-66896942-A-G		not specified	Uncertain significance (Apr 28, 2022)
8-66901311-T-G		not specified	Uncertain significance (Feb 17, 2022)
8-66901346-T-A		Male infertility with azoospermia or oligozoospermia due to single gene mutation	Likely pathogenic (Sep 01, 2023)
8-66905227-G-A		not specified	Uncertain significance (Sep 01, 2021)
8-66905251-C-T		Azoospermia	Pathogenic (Dec 20, 2021)
8-66905287-G-A		not specified	Uncertain significance (Mar 06, 2025)
8-66919058-T-G		not specified	Uncertain significance (Aug 13, 2021)
8-66919119-T-G		not specified	Uncertain significance (Mar 29, 2022)
8-66919159-G-T		not specified	Uncertain significance (Feb 13, 2025)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP

Essentials

• gene_indispensability_pred: N
• gene_indispensability_score: 0.231

Mouse Genome Informatics

• Gene name: Snhg6