TARID

TCF21 antisense RNA inducing promoter demethylation, the group of Long non-coding RNAs with non-systematic symbols

Basic information

Region (hg38): 6:133485013-133953083

Previous symbols: [ "EYA4-AS1" ]

Links

ENSG00000227954 ∙ NCBI:100507308 ∙ OMIM:616058 ∙ HGNC:50506 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the TARID gene.

• Dilated cardiomyopathy 1J (233 variants)
• not provided (101 variants)
• Autosomal dominant nonsyndromic hearing loss 10 (71 variants)
• Cardiovascular phenotype (57 variants)
• not specified (17 variants)
• Dilated cardiomyopathy 1J;Autosomal dominant nonsyndromic hearing loss 10 (11 variants)
• Inborn genetic diseases (7 variants)
• Autosomal dominant nonsyndromic hearing loss 10;Dilated cardiomyopathy 1J (4 variants)
• EYA4-related condition (4 variants)
• Dilated Cardiomyopathy, Dominant (3 variants)
• Nonsyndromic Hearing Loss, Dominant (3 variants)
• Hearing impairment (2 variants)
• EYA4-Related Disorders (1 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the TARID gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)			1			1
splice region						0
non coding	10	5	186	100	33	334
Total	10	5	187	100	33

Highest pathogenic variant AF is 0.00000657

Variants in TARID

This is a list of pathogenic ClinVar variants found in the TARID region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
6-133506010-T-C			Benign (Jun 24, 2018)
6-133506081-CATTAT-C		Dilated cardiomyopathy 1J	Likely benign (Mar 18, 2022)
6-133506086-T-C		Dilated cardiomyopathy 1J	Likely benign (Nov 22, 2022)
6-133506092-C-T		Dilated cardiomyopathy 1J	Likely benign (Jan 28, 2024)
6-133506093-A-G		Dilated cardiomyopathy 1J	Likely benign (Jan 13, 2024)
6-133506103-C-T		Dilated cardiomyopathy 1J	Uncertain significance (Oct 03, 2022)
6-133506106-G-T		Dilated cardiomyopathy 1J	Uncertain significance (May 05, 2023)
6-133506109-C-T		Dilated cardiomyopathy 1J	Uncertain significance (Oct 31, 2022)
6-133506110-C-T		Cardiovascular phenotype	Uncertain significance (Nov 19, 2021)
6-133506111-C-A		Dilated cardiomyopathy 1J • Cardiovascular phenotype	Likely benign (Mar 29, 2021)
6-133506111-C-G		Cardiovascular phenotype	Likely benign (Apr 06, 2024)
6-133506111-C-T		Dilated cardiomyopathy 1J • Cardiovascular phenotype	Likely benign (Jul 13, 2022)
6-133506116-T-C		Dilated cardiomyopathy 1J	Uncertain significance (Sep 11, 2023)
6-133506118-G-T		Cardiovascular phenotype • Dilated cardiomyopathy 1J	Uncertain significance (Apr 19, 2022)
6-133506125-C-A			Uncertain significance (Dec 21, 2023)
6-133506126-C-A		Dilated cardiomyopathy 1J • Cardiovascular phenotype	Likely benign (Dec 12, 2023)
6-133506130-G-A			Uncertain significance (Aug 24, 2022)
6-133506134-TCCGCA-T		Dilated cardiomyopathy 1J	Pathogenic (Mar 27, 2018)
6-133506135-C-T		Cardiovascular phenotype	Likely benign (Mar 09, 2022)
6-133506136-C-T		Dilated cardiomyopathy 1J • Cardiovascular phenotype	Uncertain significance (Dec 12, 2023)
6-133506137-G-A		not specified • Dilated cardiomyopathy 1J • Autosomal dominant nonsyndromic hearing loss 10 • Cardiovascular phenotype	Uncertain significance (Nov 17, 2023)
6-133506140-T-G		Dilated cardiomyopathy 1J	Uncertain significance (Apr 19, 2022)
6-133506145-G-A		Dilated cardiomyopathy 1J	Uncertain significance (May 30, 2021)
6-133506148-A-T		Dilated cardiomyopathy 1J	Uncertain significance (May 09, 2019)
6-133506152-TTTTTAATC-T		EYA4-related disorder	Pathogenic (Sep 12, 2023)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP