TRAF3IP2-AS1

TRAF3IP2 antisense RNA 1, the group of Antisense RNAs

Basic information

Region (hg38): 6:111483389-111598784

Previous symbols: [ "TRAF3IP2-AS2", "C6orf3", "NCRNA00248" ]

Links

ENSG00000231889 ∙ NCBI:643749 ∙ ∙ HGNC:40005 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the TRAF3IP2-AS1 gene.

• Candidiasis, familial, 8 (207 variants)
• Inborn genetic diseases (19 variants)
• not provided (10 variants)
• not specified (3 variants)
• Psoriasis 13, susceptibility to;Candidiasis, familial, 8 (3 variants)
• Psoriasis 13, susceptibility to (1 variants)
• Discoid lupus rash (1 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the TRAF3IP2-AS1 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding	9	2	122	72	14	219
Total	9	2	122	72	14

Highest pathogenic variant AF is 0.0000197

Variants in TRAF3IP2-AS1

This is a list of pathogenic ClinVar variants found in the TRAF3IP2-AS1 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
6-111559411-G-C		Candidiasis, familial, 8	Likely benign (Jul 13, 2020)
6-111559417-C-A		Candidiasis, familial, 8	Likely benign (Jun 03, 2023)
6-111559422-G-A		Candidiasis, familial, 8	Uncertain significance (Feb 20, 2018)
6-111559423-A-G		Candidiasis, familial, 8	Likely benign (Apr 18, 2022)
6-111559426-G-C		Candidiasis, familial, 8	Likely benign (Jun 24, 2023)
6-111559429-G-T		Candidiasis, familial, 8	Likely benign (Apr 12, 2023)
6-111559442-C-T		not specified	Uncertain significance (Jan 27, 2022)
6-111559467-C-T		Candidiasis, familial, 8	Uncertain significance (Apr 21, 2022)
6-111559489-G-A		Candidiasis, familial, 8	Benign (Jan 03, 2024)
6-111559489-G-GT		Candidiasis, familial, 8	Uncertain significance (Dec 22, 2023)
6-111559506-G-A		Candidiasis, familial, 8	Uncertain significance (Dec 11, 2023)
6-111559520-T-C		Candidiasis, familial, 8	Benign (Jan 24, 2024)
6-111559523-G-A		Candidiasis, familial, 8	Pathogenic (Oct 17, 2013)
6-111559528-C-T		Candidiasis, familial, 8	Likely benign (Aug 03, 2020)
6-111559529-T-C		Candidiasis, familial, 8	Uncertain significance (Jul 12, 2022)
6-111559535-C-G		Psoriasis 13, susceptibility to	Uncertain significance (Mar 17, 2024)
6-111559539-T-C		Candidiasis, familial, 8	Uncertain significance (Apr 03, 2021)
6-111559551-C-A		Candidiasis, familial, 8	Uncertain significance (Jun 05, 2018)
6-111559557-G-T		Candidiasis, familial, 8	Likely benign (Dec 25, 2023)
6-111562947-GT-G		Candidiasis, familial, 8	Likely benign (Dec 11, 2023)
6-111562947-GTTTC-G		Candidiasis, familial, 8	Likely benign (Jan 22, 2024)
6-111562951-C-G		Candidiasis, familial, 8	Likely benign (May 15, 2023)
6-111562951-CTTTG-C		Candidiasis, familial, 8	Likely benign (Nov 27, 2023)
6-111562986-C-T		Candidiasis, familial, 8	Likely benign (Nov 27, 2023)
6-111562992-G-A		Candidiasis, familial, 8	Likely benign (Jul 30, 2019)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP