TRIM64

tripartite motif containing 64, the group of Tripartite motif family|Ring finger proteins

Basic information

Region (hg38): 11:89966037-89974072

Previous symbols: [ "C11orf28" ]

Links

ENSG00000204450 ∙ NCBI:120146 ∙ ∙ HGNC:14663 ∙ Uniprot:A6NGJ6 ∙ AlphaFold ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the TRIM64 gene.

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the TRIM64 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense			11	1		12
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding						0
Total	0	0	11	1	0

Variants in TRIM64

This is a list of pathogenic ClinVar variants found in the TRIM64 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
11-89968571-T-A		not specified	Uncertain significance (Jun 22, 2021)
11-89968612-C-T		not specified	Uncertain significance (Jan 03, 2024)
11-89968705-G-C		not specified	Uncertain significance (Apr 25, 2022)
11-89968781-T-C		not specified	Uncertain significance (Sep 14, 2022)
11-89968837-G-A		not specified	Uncertain significance (Nov 13, 2023)
11-89968862-A-C		not specified	Uncertain significance (Jan 16, 2024)
11-89968865-T-A		not specified	Uncertain significance (Mar 16, 2024)
11-89968891-T-A		not specified	Uncertain significance (Jul 09, 2021)
11-89973453-T-G		not specified	Uncertain significance (Feb 23, 2023)
11-89973469-T-G		not specified	Uncertain significance (Feb 15, 2023)
11-89973591-A-G		not specified	Uncertain significance (Oct 29, 2021)
11-89973753-A-G		not specified	Likely benign (Apr 12, 2022)
11-89973768-T-C		not specified	Uncertain significance (Dec 18, 2023)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP

Gene ontology

• Molecular function: zinc ion binding